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Common laboratory tests as indicators of COVID-19 severity on admission at high altitude: A single-center retrospective study in Quito (ECUADOR)
OtherAbstract:Palabras claves:Biomarkers, Clinical laboratory techniques, covid-19, epidemiologyAutores:Esteban Fernández-Moreira, Francisco X. Mora, Hegira Ramírez, Kevin Chamorro, Martha M. Fors-López, Mary Pulgar-Sánchez, Santiago J. BallazFuentes:googlescopusBiomarkers of severe COVID-19 pneumonia on admission using data-mining powered by common laboratory blood tests-datasets
ArticleAbstract: In the epidemiological COVID-19 research, artificial intelligence is a unique approach to make pbkp_Palabras claves:Blood gas analyses, Clinical laboratory techniques, covid-19, Data Mining, Machine learning, Medical informatics applicationsAutores:Esteban Fernández-Moreira, Francisco X. Mora, Hegira Ramírez, Kevin Chamorro, MARTHA FORS, Martha M. Fors-López, Mary Pulgar-Sánchez, Santiago J. BallazFuentes:googlescopusA cross-sectional study to assess knowledge of covid-19 among undergraduate students in north-central Ecuador
ArticleAbstract: Adherence to preventive measures is influenced by people’s knowledge, attitudes and practices towardPalabras claves:awareness, covid-19, ECUADOR, knowledge, SARS-CoV-2 virus, Undergraduate studentsAutores:Christian Vinueza-Burgos, David Ortega-Paredes, Esteban Fernández-Moreira, Hegira Ramírez, Loaiza K., Marcelo Larrea, Marco Larrea-Alvarez, Molina-Cuasapaz G., Pedro M. Barba, Santiago Isaac Jijón, Šefcová M.A.Fuentes:scopusNovel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage
ArticleAbstract: A series of 78 synthetic 7-chloro-(4-thioalkylquinoline) derivatives were investigated for cytotoxicPalabras claves:antiproliferative activity, cell cycle, DNA/RNA damage, Sulfanyl-Sulfinyl-Sulfonyl groups, synthesis of 4-thioalkylquinolineAutores:Bruno-Colmenarez J., Charris J.E., de Sanctis J.B., Deffieux D., Džubák P., Esteban Fernández-Moreira, Gurská S., Gutiérrez J.E., Hajdůch M., Hegira Ramírez, Mijares M.R., Pouységu L., Quideau S., Rodríguez M.A., Rojas L.B.Fuentes:scopusOne-pot multicomponent synthesis of methoxybenzo[h]quinoline-3-carbonitrile derivatives; anti-chagas, X-ray, and in silico ADME/tox profiling studies
ArticleAbstract: Several methoxybenzo[h]quinoline-3-carbonitrile analogs were designed and synthesized in a repositioPalabras claves:Cáncer, chagas, Methoxybenzo[h]quinoline, One-pot synthesisAutores:Ángel J.E., Capparelli M.V., Charris J.E., Charris K.E., Esteban Fernández-Moreira, Hegira Ramírez, Nogueda-Torres B.Fuentes:scopusIn vitro evaluation and in vivo efficacy of nitroimidazole-sulfanyl ethyl derivatives against Leishmania (V.) braziliensis and Leishmania (L.) mexicana
ArticleAbstract: The aim of this study was to synthesize several small molecules of the type 5-nitroimidazole-sulfanyPalabras claves:LEISHMANIA, Metronidazole, Nitroimidazole, PCR, SulfanylAutores:Blanco Z., Charris J.E., Esteban Fernández-Moreira, Hegira Ramírez, Mijares M.R., Oviedo H.J., Rodríguez N.M.Fuentes:scopusSex-Dependent Performance of the Neutrophil-to-Lymphocyte, Monocyte-to-Lymphocyte, Platelet-to-Lymphocyte and Mean Platelet Volume-to-Platelet Ratios in Discriminating COVID-19 Severity
ArticleAbstract: Background: The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocytePalabras claves:covid-19, gender, mean platelet volume-to-platelet ratio, monocyte-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratioAutores:Esteban Fernández-Moreira, Francisco X. Mora, Hegira Ramírez, Kevin Chamorro, Martha M. Fors-López, Mary Pulgar-Sánchez, Santiago J. BallazFuentes:scopusSYNTHESIS OF 4-BENZYLSULFANYL AND 4-BENZYLSULFONYL CHALCONES. BIOLOGICAL EVALUATION AS ANTIMALARIAL AGENTS
ArticleAbstract: Malaria management has been complicated in recent times, perhaps, by increasing the Plasmodium spp.Palabras claves:Antimalarial, Chalcones, Plasmodium berghei, β-haematinAutores:Charris J.E., Domínguez J.N., Esteban Fernández-Moreira, Hegira Ramírez, Rodrigues J.R., Rodríguez M.A.Fuentes:scopusSynthesis and antimalarial and anticancer evaluation of 7-chlorquinoline-4-thiazoleacetic derivatives containing aryl hydrazide moieties
ArticleAbstract: Twelve 7-chloroquinoline derivatives were designed and synthesized using the principle of molecularPalabras claves:Antimalarial, Antiproliferative, apoptosis, hydrazides, quinoline, thiazolAutores:Celis C., Charris J.E., de Sanctis J.B., Esteban Fernandez, Hegira Ramírez, Martinez G.P., Mayora S., Mijares M.R., Rodrigues J.R.Fuentes:scopusSynthesis and biological activity of 2-[2-(7-chloroquinolin-4-ylthio)-4-methylthiazol-5-yl]-N-phenylacetamide derivatives as antimalarial and cytotoxic agents
ArticleAbstract: A novel series of 2-[2-(7-chloroquinolin-4-ylthio)-4-methylthiazol-5-yl]-N-phenylacetamide derivativPalabras claves:ANTICANCER, Antimalarial, plasmodium, quinoline, thiazoleacetic acidAutores:Charris J.E., de Sanctis J.B., Hegira Ramírez, Mijares M.R., Rodrigues J.R.Fuentes:scopus