Mostrando 10 resultados de: 12
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Article(12)
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Journal of Molecular Medicine(2)
American Journal of Physiology - Lung Cellular and Molecular Physiology(1)
American Journal of Respiratory and Critical Care Medicine(1)
Autophagy(1)
Biochemical Pharmacology(1)
Área temáticas
Enfermedades(8)
Farmacología y terapéutica(4)
Fisiología humana(4)
Fisiología y materias afines(2)
Genética y evolución(1)
Origen
scopus(12)
Clinical significance of toll-like receptor 3, 4, and 9 in gastric cancer
ArticleAbstract: Toll-like receptors (TLRs) have raised an extraordinary interest in cancer research due to their rolPalabras claves:gastric carcinoma, prognosis, tissue arrays, Toll-like receptors, tumor invasionAutores:Alina Aguirre, Del Casar J.M., Eiró N., Fernandez-Garcia B., García-Muñiz J.L., González L., González L.O., González-Reyes S., Vizoso F.J.Fuentes:scopusAnti-inflammatory effects of clarithromycin in ventilator-induced lung injury
ArticleAbstract: Background: Mechanical ventilation can promote lung injury by triggering a pro-inflammatory responsePalabras claves:E-selectin, Macrolides, Mechanical Ventilation, Neutrophil migrationAutores:Albaiceta G.M., Alina Aguirre, Amado-Rodríguez L., Astudillo A., Batalla-Solís E., Blazquez-Prieto J., García-Prieto E., González-López A., López-Alonso I.Fuentes:scopusDefective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia
ArticleAbstract: Autophagy has emerged as a key regulator of the inflammatory response. To examine the role of autophPalabras claves:ATF3 sequestration, Autophagy, Endotoxemia, Inflammatory response, Lung injury, sepsisAutores:Albaiceta G.M., Alina Aguirre, Amado-Rodríguez L., Astudillo A., Batalla-Solís E., Blazquez-Prieto J., Dos Santos C.C., Fernández A.F., Galván J.A., González-López A., López-Alonso I.Fuentes:scopusATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
ArticleAbstract: The identification of inflammatory bowel disease (IBD) susceptibility genes by genome-wide associatiPalabras claves:ATG4B, Autophagin-1, Autophagy, COLITIS, Cysteine peptidase, inflammation, Intestinal homeostasis, Paneth cellAutores:Alina Aguirre, Cabrera S., Español Y., Fernández A.F., Freije J.M.P., Fueyo A., Kroemer G., Laurà R., Lõpez-Otín C., Mariño G., Soledad Fernández-García M., Suárez M.F., Vega J.A.Fuentes:scopusDual dose-related effects evoked by CCL4 on thermal nociception after gene delivery or exogenous administration in mice
ArticleAbstract: As recently described, the administration of extremely low doses (pg/kg) of CCL4 (Macrophage inflammPalabras claves:antinociception, CCL4 (MIP-1β), cytokines, Hyperalgesia, Leukocytes, mouseAutores:Alina Aguirre, Baamonde A., García-Domínguez M., González-Rodríguez S., Gutiérrez-Fernández A., Hidalgo A., Lastra A., Menéndez L.Fuentes:scopusLoss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid
ArticleAbstract: MT1-MMP (MMP14) is a collagenolytic enzyme located at the cell surface and implicated in extracellulPalabras claves:aging, extracellular matrix, metalloprotease, Nuclear lamina, retinoidsAutores:Alina Aguirre, Fernández-García M.S., Fueyo A., Garabaya C., Gutiérrez-Abril J., Gutiérrez-Fernández A., Lõpez-Otín C., Osorio F.G., Puente X.S., Soria-Valles C.Fuentes:scopusMMP-8 deficiency increases TLR/RAGE ligands S100A8 and S100A9 and exacerbates lung inflammation during endotoxemia
ArticleAbstract: Matrix metalloproteinase-8, released mainly from neutrophils, is a critical regulator of the inflammPalabras claves:Autores:Albaiceta G.M., Alina Aguirre, Amado-Rodríguez L., Astudillo A., Batalla-Solís E., Colado E., Fernández-García M.S., González-López A., López-Alonso I., Suárez M.F.Fuentes:scopusMatrix metalloproteinase-14 triggers an anti-inflammatory proteolytic cascade in endotoxemia
ArticleAbstract: ᅟ: Matrix metalloproteinases can modulate the inflammatory response through processing of cyto- andPalabras claves:Alarmins, Endotoxemia, Matrix metalloproteinases, MMP-14, sepsisAutores:Albaiceta G.M., Alina Aguirre, Amado-Rodríguez L., Batalla-Solís E., Blazquez-Prieto J., González-López A., Gutiérrez-Fernández A., López-Alonso I., Mayoral-Garcia C., Sánchez-Pérez M.Fuentes:scopusMechanical ventilation triggers hippocampal apoptosis by vagal and dopaminergic pathways
ArticleAbstract: Rationale: Critically ill patients frequently develop neuropsychological disturbances including acutPalabras claves:BRAIN, Dysbindin, Ventilator-induced lung injuryAutores:Albaiceta G.M., Alina Aguirre, Amado-Rodríguez L., Astudillo A., Batalla-Solís E., Dos Santos C.C., Fueyo A., González-López A., López-Alonso I., Talbot K., Tomás-Zapico C.Fuentes:scopusImpairment of autophagy decreases ventilator-induced lung injury by blockade of the NF-κB pathway
ArticleAbstract: Excessive lung stretch triggers lung inflammation by activation of the NF-κB pathway. This route canPalabras claves:Autophagin-1, inflammation, IκB, Ventilator-induced lung injuryAutores:Albaiceta G.M., Alina Aguirre, Amado-Rodríguez L., Astudillo A., Batalla-Solís E., Fernández A.F., González-López A., López-Alonso I.Fuentes:scopus