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Association of the idiotype:Antiidiotype antibody ratio with the efficacy of intravenous immunoglobulin treatment for the prevention of recurrent autoimmune-associated congenital heart block
ArticleAbstract: Objective Congenital heart block (CHB), a manifestation of neonatal lupus, is associated with maternPalabras claves:Autores:Buyon J., Clancy R., Friedman D.M., Llanos C., Moutsopoulos H.M., Nikolaos C. Kyriakidis, Routsias J.G., Tzioufas A.G.Fuentes:scopusA comprehensive review of autoantibodies in primary Sjögren's syndrome: Clinical phenotypes and regulatory mechanisms
ReviewAbstract: Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by periepithelial lymphocyticPalabras claves:Anti-La/SSB, Anti-Ro/SSA, Autoantibodies, Salivary gland epithelial cells, Sjörgen's syndromeAutores:Kapsogeorgou E.K., Nikolaos C. Kyriakidis, Tzioufas A.G.Fuentes:googlescopusDiagnostic Performance of Seven Commercial COVID-19 Serology Tests Available in South America
ArticleAbstract: Background: Although RT-qPCR remains the gold-standard for COVID-19 diagnosis, anti-SARS-CoV-2 serolPalabras claves:covid-19, diagnosis, ECUADOR, Elisa, Rapid test, SARS-COV-2, serological testAutores:Alexander Paolo Vallejo-Janeta, Aquiles R. Henríquez-Trujillo, Esteban Ortiz-Prado, Ismar Alejandra Rivera-Olivero, Juan Carlos Laglaguano, Miguel Angel Garcia‑Bereguiain, Nikolaos C. Kyriakidis, Tannya LozadaFuentes:googlescopusEuropean families reveal MHC class i and II associations with autoimmune-mediated congenital heart block
OtherAbstract:Palabras claves:Autoantibodies, autoimmunity, Cardiovascular diseaseAutores:Carolis S.D., Dilthey A., Ebbing C., Eronen M., Hoxha A., Julkunen H., Kere J., Kiserud T., Kockum I., Meisgen S., Meneghel L., Nikolaos C. Kyriakidis, Ruffatti A., Salomonsson S., Wahren-Herlenius M.Fuentes:googlescopusIn silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19
ArticleAbstract: Background: There is pressing urgency to identify therapeutic targets and drugs that allow treatingPalabras claves:artificial neural networks, covid-19, drug repurposing, Immune system, single-cell RNA sequencingAutores:Adriana Granizo-Martínez, Alejandro Cabrera-Andrade, Ana Karina Zambrano, Ana María Gómez-Jaramillo, Andreina Quevedo, Andrés López-Cortés, Ángela León-Cáceres, Carlos Barba-Ostria, Cesar Paz-y-Miño, Cevallos-Robalino D., Eduardo Tejera, Esteban Ortiz-Prado, Jennyfer M. García-Cárdenas, Jhommara Bautista, Katherine Simbaña-Rivera, Lourdes Puig San Andrés, Moreno S., Munteanu C.R., Nikolaos C. Kyriakidis, P. Guevara-Ramírez, Pérez-M G., Proaño-Castro C., Quiñones L.A., Santiago Xavier Guerrero, Varela N.M., Yunierkis Perez-CastilloFuentes:scopusTracking sars-cov-2: Novel trends and diagnostic strategies
ReviewAbstract: The COVID-19 pandemic has had an enormous impact on economies and health systems globally, thereforePalabras claves:Antigen testing, Automation, covid-19, CRISPR-based diagnostics, Nanotechnology-based diagnostics, Nucleic acid amplification testAutores:Andrés López-Cortés, Carlos Barba-Ostria, Claudia G. Oña-Arias, Erick Moreta-Urbano, Jonguitud-Borrego N., Linda P. Guaman-Bautista, Malcı K., marbel torres arias, Nikolaos C. Kyriakidis, Ramos-Martinez E., Rios-Solis L.Fuentes:googlescopusType i IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
ArticleAbstract: Objective In utero exposure of the fetus to Ro/La autoantibodies may lead to congenital heart blockPalabras claves:Autoantibodies, autoimmune diseases, Sjøgren's syndromeAutores:Aronsson E., Bengtsson A.A., Bergman G., Eloranta M.L., Espinosa A.C., Gemzell-Danielsson K., Hedlund M., Ivanchenko M., Lagnefeldt L., Nikolaos C. Kyriakidis, Ottosson V., Ronnblom L., Sirsjö A., Sonesson S.E., Thorlacius G.E., Tingström J., Wahren-Herlenius M.Fuentes:googlescopusRNA recognition motif (RRM) of La/SSB: The bridge for interparticle spreading of autoimmune response to U1-RNP
ArticleAbstract: Systemic lupus erythematosus (SLE) is characterized by the production of grouped sets of autoantibodPalabras claves:Autores:Latreille M., Nikolaos C. Kyriakidis, Routsias J.G., Tzioufas A.G.Fuentes:googlescopusRole of Uremic Toxins in Early Vascular Ageing and Calcification
ReviewAbstract: In patients with advanced chronic kidney disease (CKD), the accumulation of uremic toxins, caused byPalabras claves:Cardiovascular disease, Chronic kidney disease, uremic toxins, vascular calcification, vascular smooth muscle cellsAutores:Cobo G., Dai L., Lindholm B., Nikolaos C. Kyriakidis, Stenvinkel P.Fuentes:googlescopusSARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates
ReviewAbstract: The new SARS-CoV-2 virus is an RNA virus that belongs to the Coronaviridae family and causes COVID-1Palabras claves:Autores:Alejandra Barreto Grimaldos, Andrés López-Cortés, Esteban Ortiz-Prado, Jorge Eduardo Vásconez, Nikolaos C. KyriakidisFuentes:scopus