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Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review
ReviewAbstract: Coronaviruses are an extensive family of viruses that can cause disease in both animals and humans.Palabras claves:CORONAVIRUS, covid-19, pandemic, Review, SARS-COV-2Autores:Ana María Gómez-Jaramillo, Andrés López-Cortés, Carlos Barba-Ostria, Cevallos-Robalino D., Claire Muslin, Esteban Ortiz-Prado, Gadian N., Hector Daniel Toalombo Guaman, Hugo Sanches-SanMiguel, Katherine Simbaña-Rivera, Lenin Gómez-Barreno, Linda P. Guamán, Luis Javier Unigarro, Nikolaos C. Kyriakidis, Rasa Zalakeviciute, Rubio-Neira M.Fuentes:googlescopusA comprehensive review of autoantibodies in primary Sjögren's syndrome: Clinical phenotypes and regulatory mechanisms
ReviewAbstract: Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by periepithelial lymphocyticPalabras claves:Anti-La/SSB, Anti-Ro/SSA, Autoantibodies, Salivary gland epithelial cells, Sjörgen's syndromeAutores:Kapsogeorgou E.K., Nikolaos C. Kyriakidis, Tzioufas A.G.Fuentes:googlescopusDiagnostic Performance of Seven Commercial COVID-19 Serology Tests Available in South America
ArticleAbstract: Background: Although RT-qPCR remains the gold-standard for COVID-19 diagnosis, anti-SARS-CoV-2 serolPalabras claves:covid-19, diagnosis, ECUADOR, Elisa, Rapid test, SARS-COV-2, serological testAutores:Alexander Paolo Vallejo-Janeta, Aquiles R. Henríquez-Trujillo, Esteban Ortiz-Prado, Ismar Alejandra Rivera-Olivero, Juan Carlos Laglaguano, Miguel Angel Garcia‑Bereguiain, Nikolaos C. Kyriakidis, Tannya LozadaFuentes:googlescopusE3 ubiquitin-protein ligase TRIM21-mediated lysine capture by UBE2E1 reveals substrate-targeting mode of a ubiquitin-conjugating E2
ArticleAbstract: The E3 ubiquitin-protein ligase TRIM21, of the RING-containing tripartite motif (TRIM) protein familPalabras claves:Autores:Ahlner A., Anandapadamanaban M., Csizmók V., Espinosa A.C., Moche M., Nikolaos C. Kyriakidis, Round A.R., Sunnerhagen M., Trewhella J., Wahren-Herlenius M., Wallenhammar A.Fuentes:googlescopusEuropean families reveal MHC class i and II associations with autoimmune-mediated congenital heart block
OtherAbstract:Palabras claves:Autoantibodies, autoimmunity, Cardiovascular diseaseAutores:Carolis S.D., Dilthey A., Ebbing C., Eronen M., Hoxha A., Julkunen H., Kere J., Kiserud T., Kockum I., Meisgen S., Meneghel L., Nikolaos C. Kyriakidis, Ruffatti A., Salomonsson S., Wahren-Herlenius M.Fuentes:googlescopusTracking sars-cov-2: Novel trends and diagnostic strategies
ReviewAbstract: The COVID-19 pandemic has had an enormous impact on economies and health systems globally, thereforePalabras claves:Antigen testing, Automation, covid-19, CRISPR-based diagnostics, Nanotechnology-based diagnostics, Nucleic acid amplification testAutores:Andrés López-Cortés, Carlos Barba-Ostria, Claudia G. Oña-Arias, Erick Moreta-Urbano, Jonguitud-Borrego N., Linda P. Guaman-Bautista, Malcı K., marbel torres arias, Nikolaos C. Kyriakidis, Ramos-Martinez E., Rios-Solis L.Fuentes:googlescopusType i IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
ArticleAbstract: Objective In utero exposure of the fetus to Ro/La autoantibodies may lead to congenital heart blockPalabras claves:Autoantibodies, autoimmune diseases, Sjøgren's syndromeAutores:Aronsson E., Bengtsson A.A., Bergman G., Eloranta M.L., Espinosa A.C., Gemzell-Danielsson K., Hedlund M., Ivanchenko M., Lagnefeldt L., Nikolaos C. Kyriakidis, Ottosson V., Ronnblom L., Sirsjö A., Sonesson S.E., Thorlacius G.E., Tingström J., Wahren-Herlenius M.Fuentes:googlescopusRNA recognition motif (RRM) of La/SSB: The bridge for interparticle spreading of autoimmune response to U1-RNP
ArticleAbstract: Systemic lupus erythematosus (SLE) is characterized by the production of grouped sets of autoantibodPalabras claves:Autores:Latreille M., Nikolaos C. Kyriakidis, Routsias J.G., Tzioufas A.G.Fuentes:googlescopusRole of Uremic Toxins in Early Vascular Ageing and Calcification
ReviewAbstract: In patients with advanced chronic kidney disease (CKD), the accumulation of uremic toxins, caused byPalabras claves:Cardiovascular disease, Chronic kidney disease, uremic toxins, vascular calcification, vascular smooth muscle cellsAutores:Cobo G., Dai L., Lindholm B., Nikolaos C. Kyriakidis, Stenvinkel P.Fuentes:googlescopusStudy of microRNAs (miRNAs) that are pbkp_redicted to target the autoantigens Ro/SSA and La/SSB in primary Sjögren's Syndrome
ArticleAbstract: The elevated tissue expression of Ro/SSA and La/SSB autoantigens appears to be crucial for the generPalabras claves:Autoantigens, La/SSB, miRNAs, Ro52/TRIM21, Ro60/TROVE2, Sjögren's syndromeAutores:Gourzi V.C., Kapsogeorgou E.K., Nikolaos C. Kyriakidis, Tzioufas A.G.Fuentes:googlescopus