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Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion
ArticleAbstract: The strength and spatiotemporal activity of Nodal signaling is tightly controlled in early implantatPalabras claves:Amnion, Bone Morphogenetic Protein, mouse, Nodal, Primitive streak, SmadAutores:Camus A., Cornelis F.M., de Sousa Lopes S.M.C., Dobreva M.P., Huylebroeck D., Iván M. Moya, Maas E., Pereira P.N.G., Umans L., Verfaillie C.M., Zwijsen A.Fuentes:googlescopusDifferential regulation of the Hippo pathway by adherens junctions and apical- Basal cell polarity modules
ArticleAbstract: Adherens junctions (AJs) and cell polarity complexes are key players in the establishment and maintePalabras claves:Autores:Gladden A.B., Graves H.K., Halder G., Hamaratoglu F., Iván M. Moya, Tao C., Yang C.C.Fuentes:googlescopusHippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
ReviewAbstract: The Hippo pathway and its downstream effectors, the transcriptional co-activators Yes-associated proPalabras claves:Autores:Halder G., Iván M. MoyaFuentes:googlescopusFew Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo
ReviewAbstract: Signaling by the many ligands of the TGFβ family strongly converges towards only five receptor-activPalabras claves:CPSF, Sip1, Smad, Tdp2, Transforming growth factor βAutores:Beets K., Cazzola S., Coddens K., Collart C., Conidi A., Cornelis F.M., Cox L., Dobreva M.P., Dries R., Esguerra C.V., Francis A., Huylebroeck D., Ibrahimi A., Iván M. Moya, Joke D., Kroes R., Lesage F., Maas E., Pereira P.N.G., Seuntjens E., Stappers E., Stryjewska A., Umans L., van den Berghe V., Vermeire L., Verstappen G., Zwijsen A.Fuentes:googlescopusRegeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis
ArticleAbstract: Background and Aims: The Hippo pathway and its downstream effectors YAP and TAZ (YAP/TAZ) are heraldPalabras claves:Biliary Epithelial Cells, Cholangiocytes, hippo pathway, Toxic InjuryAutores:Algueró-Nadal A., Bergers G., Castaldo S.A., Halder G., Hillen H., Iván M. Moya, Kowalczyk W., Lambrechts D., Lemaigre F.P., Mercader-Celma C., Romanelli L., Roskams T., Sansores-Garcia L., Soheily S., Souza N.A., Van Brussel T., van Grunsven L.A., Van Huffel L., Vella G., Verboven E., Verhulst S., Xie J.Fuentes:googlescopusRobustness in angiogenesis: Notch and BMP shaping waves
ReviewAbstract: Vascular patterning involves sprouting of blood vessels, which is governed by orchestrated communicaPalabras claves:Angiogenesis, Endothelial cell competence, Hypersprouting, Lateral inhibition, Oscillatory gene expression, PlasticityAutores:Beets K., Huylebroeck D., Iván M. Moya, Umans L., Zwijsen A.Fuentes:googlescopusStalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades
ArticleAbstract: Gradients of vascular endothelial growth factor (VEGF) induce single endothelial cells to become leaPalabras claves:Autores:Beets K., Francis A., Huylebroeck D., Iván M. Moya, Maas E., Mummery C., Pereira P.N.G., Robertson E., Sents W., Umans L., Zwijsen A.Fuentes:googlescopusThe Hippo pathway in cellular reprogramming and regeneration of different organs
ReviewAbstract: We have a limited ability to stimulate cells in damaged tissues to regenerate properly patterned andPalabras claves:Autores:Halder G., Iván M. MoyaFuentes:googlescopusYAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
ArticleAbstract: Vascular endothelial growth factor (VEGF) is a major driver of blood vessel formation. However, thePalabras claves:Angiogenesis, CNS vascularization, endothelial cells, hippo pathway, TAZ, VEGF, VEGFR2, YAP, YAP/TAZAutores:Castro L., Fischer T., Freire Valls A., Halder G., Iván M. Moya, Jain R.K., Mazzone M., Riedemann L., Ruiz de Almodóvar C., Schermann G., Schmidt T., Shen Y., Solecki G.M., Urban S., Wang X., Winkler F.Fuentes:googlescopus