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Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion
ArticleAbstract: The strength and spatiotemporal activity of Nodal signaling is tightly controlled in early implantatPalabras claves:Amnion, Bone Morphogenetic Protein, mouse, Nodal, Primitive streak, SmadAutores:Camus A., Cornelis F.M., de Sousa Lopes S.M.C., Dobreva M.P., Huylebroeck D., Iván M. Moya, Maas E., Pereira P.N.G., Umans L., Verfaillie C.M., Zwijsen A.Fuentes:googlescopusDifferential regulation of the Hippo pathway by adherens junctions and apical- Basal cell polarity modules
ArticleAbstract: Adherens junctions (AJs) and cell polarity complexes are key players in the establishment and maintePalabras claves:Autores:Gladden A.B., Graves H.K., Halder G., Hamaratoglu F., Iván M. Moya, Tao C., Yang C.C.Fuentes:googlescopusFunctionality based method for simultaneous isolation of rodent hepatic sinusoidal cells
ArticleAbstract: Chronic liver disease is the result of long term exposure to viruses or toxins such as alcohol, fatPalabras claves:FACS, Hepatic stellate cells, IGG, Kupffer cells, Liver sinusoidal endothelial cells, ScavengingAutores:Halder G., Iván M. Moya, Mannaerts I., Roosens T., Stradiot L., van Grunsven L.A., Verhulst S., Øie C.I.Fuentes:googlescopusHippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
ReviewAbstract: The Hippo pathway and its downstream effectors, the transcriptional co-activators Yes-associated proPalabras claves:Autores:Halder G., Iván M. MoyaFuentes:googlescopusFew Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo
ReviewAbstract: Signaling by the many ligands of the TGFβ family strongly converges towards only five receptor-activPalabras claves:CPSF, Sip1, Smad, Tdp2, Transforming growth factor βAutores:Beets K., Cazzola S., Coddens K., Collart C., Conidi A., Cornelis F.M., Cox L., Dobreva M.P., Dries R., Esguerra C.V., Francis A., Huylebroeck D., Ibrahimi A., Iván M. Moya, Joke D., Kroes R., Lesage F., Maas E., Pereira P.N.G., Seuntjens E., Stappers E., Stryjewska A., Umans L., van den Berghe V., Vermeire L., Verstappen G., Zwijsen A.Fuentes:googlescopusMask is required for the activity of the hippo pathway effector Yki/YAP
ArticleAbstract: The Drosophila Yorkie (Yki) protein and its mammalian homolog Yes-associated protein (YAP) are potenPalabras claves:Autores:Atkins M., Halder G., Iván M. Moya, Mills G.B., Sansores-Garcia L., Shahmoradgoli M., Tao C.Fuentes:googlescopusThe Hippo pathway in cellular reprogramming and regeneration of different organs
ReviewAbstract: We have a limited ability to stimulate cells in damaged tissues to regenerate properly patterned andPalabras claves:Autores:Halder G., Iván M. MoyaFuentes:googlescopusYAP and TAZ heterogeneity in primary liver cancer: An analysis of its prognostic and diagnostic role
ArticleAbstract: Primary liver cancer comprises a diverse group of liver tumors. The heterogeneity of these tumors isPalabras claves:CCA, CHCC-CCA, HCC, Hepatic progenitor cells, Keratin 19, TAZ, YAPAutores:Govaere O., Halder G., Iván M. Moya, Karaman R., Monbaliu D., Nevens F., Rens G., Roskams T., Snoeck J., Topal B., van Haele M., Verslype C.Fuentes:googlescopus