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Article(8)
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Molecules(4)
International Journal of Molecular Sciences(2)
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Antifungal activity of n-(4-halobenzyl)amides against candida spp. and molecular modeling studies
ArticleAbstract: Fungal infections remain a high-incidence worldwide health problem that is aggravated by limited thePalabras claves:Anticandidal drugs, antimicrobial activity, Benzoic acid, Candida auris, Candidiasis, cinnamic acid, fungi, Molecular docking, Natural products, plantsAutores:da Silva C.R., Dias C.d.S., Duarte A.B.S., Júnior H.V.N., Montes R.C., Neto J.B.d.A., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusArticle bioactive terpenes and their derivatives as potential SARS-CoV-2 proteases inhibitors from molecular modeling studies
ArticleAbstract: The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel coronavirus; the Severe AcutePalabras claves:covid-19, MERS-CoV, Middle East Respiratory Syndrome Virus, Natural products, plants, saponins, SARS-CoV, SARS-COV-2, Terpenoid, virusesAutores:Bezerra Filho C.d.S.M., Diniz L.R.L., Elshabrawy H.A., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusAlkyl and aryl derivatives based on p-coumaric acid modification and inhibitory action against leishmania braziliensis and plasmodium falciparum
ArticleAbstract: In low-income populations, neglected diseases are the principal cause of mortality. Of these, leishmPalabras claves:Antiplasmodial activity, Cytotoxicity, Hydroxycinnamic acids, Leishmanicidal activity, Natural products, Neglected diseasesAutores:Lopes S.P., Robledo S.M., Sousa D.P.D., Yepe L.M., Yunierkis Perez-CastilloFuentes:googlescopusGallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies
ArticleAbstract: Eight gallic acid alkyl esters (1–8) were synthesized via Fischer esterification and evaluated for tPalabras claves:gallic acid alkyl ester, Leishmania major, Leishmanicidal activity, Molecular docking, molecular dynamics simulations, Natural products, trypanocidal activity, Trypanosoma bruceiAutores:do Nascimento L.G., Sousa D.P.D., Steverding D., Yunierkis Perez-CastilloFuentes:googlescopusLarvicidal Activity of Cinnamic Acid Derivatives: Investigating Alternative Products for Aedes aegypti L. Control
ArticleAbstract: The mosquito Aedes aegypti transmits the virus that causes dengue, yellow fever, Zika and ChikungunyPalabras claves:CHIKUNGUNYA, cinnamic ester, DENGUE, Larvicidal activity, Medicinal Plants, Mosquitoes, Natural products, Yellow fever, zikaAutores:Araújo M.O., Nunes F.C., Oliveira L.H.G., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusMolecular Modeling and In Vitro Evaluation of Piplartine Analogs against Oral Squamous Cell Carcinoma
ArticleAbstract: Cancer is a principal cause of death in the world, and providing a better quality of life and reduciPalabras claves:alkaloid, ANTICANCER, antitumor, Cytotoxicity, Medicinal Plants, Natural products, Piper, PiplartineAutores:da Fonseca A.C.C., Eduardo Tejera, Machado T.Q., Robbs B.K., Silva R.H.N., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusTrypanocidal mechanism of action and in silico studies of p-coumaric acid derivatives
ArticleAbstract: Trypanosoma species are responsible for chronic and systemic infections in millions of people aroundPalabras claves:antiparasitic activity, cinnamic acid, esters, Natural products, Neglected diseases, Phenylpropanoid, TrypanosomaAutores:De Almeida R.N., de Menezes R.R.P.P.B., Lopes S.P., Martins A.M.C., Monteiro M.L., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusSynthesis of Coumarin and Homoisoflavonoid Derivatives and Analogs: The Search for New Antifungal Agents
ArticleAbstract: A set of twenty-four synthetic derivatives, with coumarin and homoisoflavonoid cores and structuralPalabras claves:Antimicrobial, Candida, coumarin, drug, flavonoid, mechanism of action, Medicinal Plant, Molecular docking, Natural productsAutores:Alves D.d.N., De Castro R.D., Ferreira A.R., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopus