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Antileishmanial Activity of Cinnamic Acid Derivatives against Leishmania infantum
ArticleAbstract: Leishmania infantum is the etiological agent of visceral leishmaniasis (VL) in South America, the MePalabras claves:antiparasitic activity, cinnamamide, cinnamate, Medicinal Plant, Natural productAutores:Almeida F.S., de Morais M.C., Keesen T.d.S.L., Medeiros G.A., Rocha J.d.C., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusA multi-objective approach for drug repurposing in preeclampsia
ArticleAbstract: Preeclampsia is a hypertensive disorder that occurs during pregnancy. It is a complex disease with uPalabras claves:Drugs repurposing, Machine learning, Multi-objective models, PreeclampsiaAutores:Alejandro Cabrera-Andrade, Andrea Chamorro, Eduardo Tejera, Sánchez M.E., Yunierkis Perez-CastilloFuentes:scopusAlkyl and aryl derivatives based on p-coumaric acid modification and inhibitory action against leishmania braziliensis and plasmodium falciparum
ArticleAbstract: In low-income populations, neglected diseases are the principal cause of mortality. Of these, leishmPalabras claves:Antiplasmodial activity, Cytotoxicity, Hydroxycinnamic acids, Leishmanicidal activity, Natural products, Neglected diseasesAutores:Lopes S.P., Robledo S.M., Sousa D.P.D., Yepe L.M., Yunierkis Perez-CastilloFuentes:googlescopusGallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies
ArticleAbstract: Eight gallic acid alkyl esters (1–8) were synthesized via Fischer esterification and evaluated for tPalabras claves:gallic acid alkyl ester, Leishmania major, Leishmanicidal activity, Molecular docking, molecular dynamics simulations, Natural products, trypanocidal activity, Trypanosoma bruceiAutores:do Nascimento L.G., Sousa D.P.D., Steverding D., Yunierkis Perez-CastilloFuentes:googlescopusDrugs Repurposing Using QSAR, Docking and Molecular Dynamics for Possible Inhibitors of the SARS-CoV-2 M<sup>pro</sup> Protease
ArticleAbstract: Wuhan, China was the epicenter of the first zoonotic transmission of the severe acute respiratory syPalabras claves:covid-19, Drugs repurposing, molecular dynamics, QSAR, SARS-COV-2Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Eduardo Tejera, Munteanu C.R., Yunierkis Perez-CastilloFuentes:googlescopusNFBTA: A potent cytotoxic agent against glioblastoma
ArticleAbstract: Piplartine (PPL), also known as piperlongumine, is a biologically active alkaloid extracted from thePalabras claves:Analogue, ANTICANCER, Antiglioblastoma therapy, Piper, PiplartineAutores:De Almeida R.N., Eduardo Tejera, Filho C.D.S.M.B., Nóbrega F.R., Ozdemir O., Sousa D.P.D., Turkez H., Yunierkis Perez-CastilloFuentes:googlescopusLarvicidal Activity of Cinnamic Acid Derivatives: Investigating Alternative Products for Aedes aegypti L. Control
ArticleAbstract: The mosquito Aedes aegypti transmits the virus that causes dengue, yellow fever, Zika and ChikungunyPalabras claves:CHIKUNGUNYA, cinnamic ester, DENGUE, Larvicidal activity, Medicinal Plants, Mosquitoes, Natural products, Yellow fever, zikaAutores:Araújo M.O., Nunes F.C., Oliveira L.H.G., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusMolecular Modeling and In Vitro Evaluation of Piplartine Analogs against Oral Squamous Cell Carcinoma
ArticleAbstract: Cancer is a principal cause of death in the world, and providing a better quality of life and reduciPalabras claves:alkaloid, ANTICANCER, antitumor, Cytotoxicity, Medicinal Plants, Natural products, Piper, PiplartineAutores:da Fonseca A.C.C., Eduardo Tejera, Machado T.Q., Robbs B.K., Silva R.H.N., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusQuinolinecarboxamides inhibit the replication of the bovine viral diarrhea virus by targeting a hot spot for the inhibition of pestivirus replication in the RNA-dependent RNA polymerase
ArticleAbstract: The bovine viral diarrhea virus (BVDV), a pestivirus from the family of Flaviviridae is ubiquitous aPalabras claves:Bovine viral diarrhea virus, RNA-dependent RNA polymerase, Substituted quinolinecarboxamide inhibitorsAutores:Froeyen M., Leyssen P., Muigg A., Musiu S., Neyts J., Paeshuyse J., Pürstinger G., Yunierkis Perez-CastilloFuentes:googlescopusSynthetic Cinnamides and Cinnamates: Antimicrobial Activity, Mechanism of Action, and In Silico Study
ArticleAbstract: The severity of infectious diseases associated with the resistance of microorganisms to drugs highliPalabras claves:amides, Antimicrobial, Candida, cinnamic acid, esters, mechanism of action, Medicinal Plant, Molecular docking, Natural product, S. AureusAutores:de Morais M.C., de Oliveira Lima E., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopus