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Forensic Science International: Genetics Supplement Series(20)
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Chemoinformatics profiling of the chromone nucleus as a MAO-B/A<inf>2A</inf>AR dual binding scaffold
ArticleAbstract: Background: In the context of the current drug discovery efforts to find disease modifying therapiesPalabras claves:A adenosine receptor 2A, chemoinformatics, Chromones, Dual-target binder, Monoamine Oxidase B, Parkinson’s DiseaseAutores:Aminael Sánchez-Rodríguez, Borges F., Cesar Paz-y-Miño, Eduardo Tejera, Maykel Cruz-Monteagudo, Morales-Helguera A., Natalia Dias Soeiro Cordeiro M., Perera-Sardiña Y., Yunierkis Perez-CastilloFuentes:googlescopusChromosome and DNA damage analysis in individuals occupationally exposed to pesticides with relation to genetic polymorphism for CYP 1A1gene in Ecuador
ArticleAbstract: DNA damage was measured by using the alkaline comet assay and the chromosomal aberration (CA) test uPalabras claves:comet assay, CYP 1A1, Gene, PESTICIDESAutores:Arévalo M., Cesar Paz-y-Miño, María-Eugenia Sánchez, Paola E. LeoneFuentes:googlescopusChromosome fragility in lymphocytes of women with cervical uterine lesions produced by human papillomavirus
ArticleAbstract: We studied 30 women with cervical lesions that showed human papillomavirus infection (HPV). CervicalPalabras claves:Autores:Cesar Paz-y-Miño, Narváez L., Narváez R., Ocampo L.Fuentes:googlescopusClinical, cytogenetic, and molecular findings in a patient with ring chromosome 4: Case report and literature review
ArticleAbstract: Background: Since 1969, 49 cases have been presented on ring chromosome 4. All of these cases have bPalabras claves:46,XX,r(4)(p16.3q35.2), FISH, inv dup del rearrangement, Mapping array, Mosaic, Ring chromosome 4Autores:Ana Proaño, Cesar Paz-y-Miño, García J.L., Hernández-Rivas J.M., Paola E. Leone, Stella D. VerdezotoFuentes:googlescopusComparative study of chromosome aberrations induced with aphidicolin in women affected by breast cancer and cervix uterine cancer
ArticleAbstract: Blood samples were obtained from 80 women: Twenty of these samples were from women affected by ductaPalabras claves:Autores:Cesar Paz-y-Miño, Córdova A., Gutiérrez-Enríquez S., Ocampo L., Paola E. Leone, Peñaherrera M.S., Sánchez M.E.Fuentes:googlescopusAssociation among polymorphisms in the steroid 5α-reductase type II (SRD5A2) gene, prostate cancer risk, and pathologic characteristics of prostate tumors in an Ecuadorian population
ArticleAbstract: Androgens are essential to normal prostate growth and development. It is therefore possible that polPalabras claves:Autores:Arévalo M., Cesar Paz-y-Miño, Díaz M., Llumipanta W., Paulo Robles, Witte T.Fuentes:scopusAssociation of genetic variants of membrane receptors related to recognition and induction of immune response with Helicobacter pylori infection in Ecuadorian individuals
ArticleAbstract: Helicobacter pylori (Hp) has a worldwide distribution showing its higher prevalence of infection inPalabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Gabriela Fernanda Jaramillo-Koupermann, María José G. Muñoz, O. Rodriguez, Paola E. LeoneFuentes:googlescopusB3/A3 rearrangement in a patient with chronic myeloid leukemia [1]
OtherAbstract: The role of BCR/ABL isoforms and their relationships to leukemia phenotype are discussed continuouslPalabras claves:B3/A3, BCR/ABL, CML, INFαAutores:Arévalo M., Cesar Paz-y-Miño, Paola E. LeoneFuentes:googlescopusBCR-ABL rearrangement frequencies in chronic myeloid leukemia and acute lymphoblastic leukemia in Ecuador, South America
ArticleAbstract: Different BCR-ABL transcript variants occur more or less frequently, according to the leukemia type.Palabras claves:Autores:Burgos R.I., Cesar Paz-y-Miño, Fiallo B.F., Morillo S.A., Paola E. Leone, Paz-Y-Mio C., Santos J.C.Fuentes:googlescopusBaseline determination in social, health, and genetic areas in communities affected by glyphosate aerial spraying on the northeastern Ecuadorian border
ArticleAbstract: The northeastern Ecuadorian border has undergone aerial spraying with an herbicide mix that containsPalabras claves:Arg399Gln, GPX-1, GSTP1, Ile105Val, Pro198leu, XRCC1Autores:Andrés López-Cortés, Cesar Paz-y-Miño, Herrera C., Maldonado A., María José G. Muñoz, María-Eugenia Sánchez, Nadia Cumbal, Paulo Robles, Valladares C.Fuentes:scopus