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Cloning and sequence analysis of the genes encoding the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus
ArticleAbstract: A 2641‐bp EcoRl fragment of DNA that encodes the C‐terminal part of the dihydrolipoyl acetyltransferPalabras claves:Autores:Adolfo Borges, HAWKINS C., Packman L., Perham R.N.Fuentes:scopusAn overview of Tityus cisandinus scorpion venom: Transcriptome and mass fingerprinting reveal conserved toxin homologs across the Amazon region and novel lipolytic components
ArticleAbstract: Tityus cisandinus, a neglected medically important scorpion in Ecuadorian and Peruvian Amazonia, belPalabras claves:antivenom, Envenomation, Ion channel toxins, Scorpion, scorpion venom, TityusAutores:Adolfo Borges, Chávez-Olórtegui C., Conceição I.M.C.A., Kalapothakis E., Kalapothakis Y., Larangote D., Miranda K., Molina D.A.M., Op den Camp H.J.M.Fuentes:scopusAntigenic, microbicidal and antiparasitic properties of an l-amino acid oxidase isolated from Bothrops jararaca snake venom
ArticleAbstract: Venoms from the bee Apis mellifera, the caterpillar Lonomia achelous, the spiders Lycosa sp. and PhoPalabras claves:Bothrops jararaca, l-Amino acid oxidase, Leishmanicidal, Microbicidal, Neutralizing potencyAutores:Adolfo Borges, Chávez-Olórtegui C., Ciscotto P., Coelho E., de Carvalho M., Diniz C., Farías L., Machado-de-Ávila R.A., Maria W., Oliveira J., Sánchez E.Fuentes:scopusA common structural motif in thiamin pyrophosphate-binding enzymes
ArticleAbstract: The amino acid sequences of a wide range of enzymes that utilize thiamin pyrophosphate (TPP) as cofaPalabras claves:Pyruvate decarboxylase, Pyruvate dehydrogenase complex, Sequence homology, Structural motif, Thiamin pyrophosphate, TransketolaseAutores:Adolfo Borges, HAWKINS C., Perham R.N.Fuentes:scopusAmino acid sequence analysis of the lipoyl and peripheral subunit-binding domains in the lipoate acetyltransferase component of the pyruvate dehydrogenase complex from Bacillus stearothermophilus.
ArticleAbstract: The pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus comprises a structurPalabras claves:Autores:Adolfo Borges, Packman L., Perham R.N.Fuentes:scopusGlutathionylspermidine metabolism in Escherichia coli
ArticleAbstract: Intracellular levels of glutathione and glutathionylspermidine conjugates have been measured throughPalabras claves:Autores:Adolfo Borges, Ariyanayagam M.R., Fairlamb A.H., Smith K.Fuentes:scopusDiversity of long-chain toxins in Tityus zulianus and Tityus discrepans venoms (Scorpiones, Buthidae): Molecular, immunological, and mass spectral analyses
ArticleAbstract: In Venezuela, stings by Tityus zulianus scorpions produce cardiorespiratory arrest, whereas envenomiPalabras claves:3′-UTR, antivenom, Mass spectrometry, scorpion toxin, scorpion venom, Tityus discrepans, Tityus zulianus, Toxin diversity, VENEZUELAAutores:Adolfo Borges, Alfonzo M.J., García C.C., Jowers M.J., Lugo E., Op den Camp H.J.M.Fuentes:scopusInactivated state dependence of sodium channel modulation by β-scorpion toxin
ArticleAbstract: We have examined the effects of a β-scorpion toxin purified from the venom of the Venezuelan scorpioPalabras claves:Channel gating, Inactivation mutant, Sodium channel, Xenopus oocyte, β-Scorpion toxinAutores:Adolfo Borges, Backx P., Tsushima R.Fuentes:scopusImpact of regional variation in Bothrops asper snake venom on the design of antivenoms: Integrating antivenomics and neutralization approaches
ArticleAbstract: Intraspecific snake venom variations have implications in the preparation of venom pools for the genPalabras claves:antivenom, Antivenomics, Bothrops asper, Phospholipase A 2, Snake venom metalloproteinase, Snake venom proteome, Venom neutralization assays, venomicsAutores:Adolfo Borges, Alape-Girón A., Calvete J.J., Estrada R., Figueroa L., Flores-Díaz M., Gutiérrez J.M., Herrera M., León G., Madrigal M., Sanz L., Villalta M.Fuentes:scopusMolecular and biochemical characterization of a CNP-sensitive guanylyl cyclase in bovine tracheal smooth muscle
ArticleAbstract: Muscarinic activation of bovine tracheal smooth muscle (BTSM) is involved in cyclic guanosine monophPalabras claves:Autores:Adolfo Borges, Alfonzo M.J., González de Alfonzo R., Lippo de Béemberg I., Sánchez de Villarroel S., Winand N.J.Fuentes:scopus