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OtherAbstract:Palabras claves:Autores:Adrián LLerena, Jiménez M., Muñoz Sanz A., Sáenz de Santamaría J.Fuentes:scopusHigh frequency and founder effect of the CYP3A4∗20 loss-of-function allele in the Spanish population classifies CYP3A4 as a polymorphic enzyme
ArticleAbstract: Cytochrome P450 3A4 (CYP3A4) is a key drug-metabolizing enzyme. Loss-of-function variants have beenPalabras claves:Autores:Adrián LLerena, Apellániz-Ruiz M., Carracedo Á., Cascón A., Comino-Méndez I., Currás-Freixes M., De Cubas A.A., Grazina M., Ingelman-Sundberg M., Inglada-Pérez L., Mancikova V., Moya G.E., Naranjo M.E.G., Opocher G., Rasool M., Rebai A., Robledo M., Rodríguez-Antona C., Sánchez L., Taboada-Echalar P., Triki S.Fuentes:scopusHigh risk of lifetime history of suicide attempts among CYP2D6 ultrarapid metabolizers with eating disorders
OtherAbstract:Palabras claves:Autores:Adrián LLerena, Agüera Z., Dorado P., Estivill X., Fernández‐aranda F., Gratacòs M., Penãs-Lledó E.M.Fuentes:scopusHigh risk of polydipsia and water intoxication in schizophrenia patients
OtherAbstract:Palabras claves:Autores:Adrián LLerena, De la Rubia A., González I., Penãs-Lledó E.M., Pérez N.Fuentes:scopusElevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment
ArticleAbstract: The polymorphic CYP2C19 enzyme metabolizes psychoactive compounds and is expressed in the adult livePalabras claves:Autores:Adrián LLerena, Baune B.T., Binder E.B., Carrillo-Roa T., Courtet P., Dannlowski U., de Quervain D.J., Ingelman-Sundberg M., Jukić M.M., Miksys S., Novalen M., Opel N., Papassotiropoulos A., Penãs-Lledó E.M., Renblom A., Sim S.C., Ström J., Tyndale R.F.Fuentes:scopusErratum: CYP2D6 ultrarapid metabolism and early dropout from fluoxetine or amitriptyline monotherapy treatment in major depressive patients (Molecular Psychiatry (2013) 18 (266))
OtherAbstract:Palabras claves:Autores:Adrián LLerena, Alonso E., Dorado P., Jung H., López-López M., Naranjo M.E.G., Ortega A., Penãs-Lledó E.M., Trejo H.D.Fuentes:scopusErratum: Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment (Molecular Psychiatry, (2017), 22, 8, (1155-1163), 10.1038/mp.2016.204)
OtherAbstract: Correction to: Molecular Psychiatry advance online publication, 29 November 2016; doi: 10.1038/mp.20Palabras claves:Autores:Adrián LLerena, Baune B.T., Binder E.B., Carrillo-Roa T., Courtet P., Dannlowski U., de Quervain D.J., Ingelman-Sundberg M., Jukić M.M., Miksys S., Novalen M., Opel N., Papassotiropoulos A., Penãs-Lledó E.M., Renblom A., Sim S.C., Ström J., Tyndale R.F.Fuentes:scopusErratum: Schizophrenia and tobacco smoking in a Spanish psychiatric hospital (Schizophrenia Research (2002) 58 (323-327) PII: S09209964010032)
OtherAbstract:Palabras claves:Autores:Adrián LLerena, De la Rubia A., De Leon J., Diaz F.J., Penãs-Lledó E.M.Fuentes:scopusFixed combinations of neuroleptics with antidepressants: potential risks and estimation of use.
ArticleAbstract:Palabras claves:Autores:Adrián LLerena, Kiivet R.A.Fuentes:scopusEvaluation of drug-metabolizing enzyme hydroxylation phenotypes in Hispanic populations: The CEIBA cocktail
ReviewAbstract: Interindividual differences in response to drug treatments are mainly caused by differences in drugPalabras claves:Cocktail, Cytochrome P450 (CYP), Genotype, Hispanics, PhenotypeAutores:Adrián LLerena, Alonso-Vilatela E., Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes-Garro C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Enrique Terán, Estévez-Carrizo F.E., Ferreiro V., Fiedler J., Francisco J.López Hernández, Galaviz-Hernandez C., Garza-Ocañas L., González-Vacarezza N., Grazina M., Herrera L., Jiménez-Arce G., LARES, Lazalde-Ramos B.P., Leonardo J. Beltrán, López-López M., Monroy-Jaramillo N., Moya G.E., Naranjo M.E.G., Natalia Heras, Ochoa-Morales A., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Rodeiro I., Rojas-Martinez A., Rojas-Ponce R., Sarmiento A.P., Sosa-Macías M.G., Tarazona-Santos E.M., Vázquez T.C., Yescas-Gómez P.Fuentes:scopus