Mostrando 10 resultados de: 37
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Pharmacogenomics(8)
Pharmacogenomics Journal(6)
OMICS A Journal of Integrative Biology(3)
European Journal of Clinical Pharmacology(2)
Journal of Clinical Psychopharmacology(2)
Assessing clinical and functional outcomes in a gene-environment interaction study in first episode of psychosis (PEPs)
ArticleAbstract: The PEPs study is a multicenter, naturalistic, prospective, longitudinal study designed to evaluatePalabras claves:First episode of psychosis, Functional assessment, outcome measures, Psychopathology assessment, SchizophreniaAutores:Adrián LLerena, Arango C., Bernardo M., Bioque M., Cabrera B., Castro-Fornieles J., Cuesta M.J., Parellada M., Saiz-Ruiz J., Sanjuán J.Fuentes:scopusAssociation of common genetic variants with risperidone adverse events in a Spanish schizophrenic population
ArticleAbstract: Risperidone non-compliance is often high due to undesirable side effects, whose development is in paPalabras claves:Adverse events, Antipsychotic, pharmacogenetics, RisperidoneAutores:Abad-Santos F., Adrián LLerena, Almoguera B., Ayuso C., Baca-García E., Dal-Ré R., Dorado P., Fernandez-Piqueras J., Lopez-Castroman J., Riveiro-Alvarez R., Vaquero-Lorenzo C.Fuentes:scopusA combined high CYP2D6-CYP2C19 metabolic capacity is associated with the severity of suicide attempt as measured by objective circumstances
ArticleAbstract: This study examined, for the first time, whether a high CYP2D6-CYP2C19 metabolic capacity combinatioPalabras claves:Autores:Adrián LLerena, Blasco-Fontecilla H., Courtet P., Delgado A., Guillaume S., Jaussent I., Naranjo M.E.G., Penãs-Lledó E.M.Fuentes:scopusDevelopment of a new genotyping assay for detection of the BDNF Val66Met polymorphism using melting-curve analysis
ArticleAbstract: Brain-derived neurotrophic factor (BDNF) plays critical role in the growth, differentation and surviPalabras claves:BDNF, Melting curve, Schizophrenia patients, SYBR, Val66Met polymorphismAutores:Adrián LLerena, Dorado P., Guarino E., Sánchez-Romero M.A.Fuentes:scopusDEBRISOQUINE HYDROXYLATION PHENOTYPES IN HEALTHY VOLUNTEERS
OtherAbstract:Palabras claves:Autores:Adrián LLerena, Benitez Rodriguez J., Cobaleda J.Fuentes:scopusCYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population
ArticleAbstract: Purpose: Cytochrome P450 2D6 (CYP2D6) genotypes and the dextromethorphan/dextrorphan (DXM/DXT) metabPalabras claves:CYP2D6, dextromethorphan, ECUADOR, pharmacogeneticsAutores:Adrián LLerena, Dorado P., Enrique Terán, Francisco J.López Hernández, Machín E., Natalia HerasFuentes:scopusCYP2D6-1584C>G promoter polymorphism and debrisoquine ultrarapid hydroxylation in healthy volunteers
ArticleAbstract: Background & aim: The CYP2D6-1584C>G polymorphism (rs1080985) has been identified as a major factorPalabras claves:1584C>G, CYP2D6, debrisoquine, Healthy volunteers, ultrarapid metabolismAutores:Adrián LLerena, Alvárez M., Calzadilla L.R., Dorado P., González I., Naranjo M.E.G., Penãs-Lledó E.M., Pérez B., Ramirez R.Fuentes:scopusCYP450 genotype and pharmacogenetic association studies: A critical appraisal
ReviewAbstract: Despite strong pharmacological support, association studies using genotype-pbkp_redicted phenotype aPalabras claves:drug metabolizing enzymes, ethnicity, Genotype, pharmacogenetic association studies, pharmacogenetics, phenoconversion, Phenotype, substrate-selectivity, Therapeutic drug monitoringAutores:Adrián LLerena, Eichelbaum M., Gaedigk A., Shah R.R., Smith R.L., Stingl J.C.Fuentes:scopusAripiprazole-induced parkinsonism and its association with dopamine and serotonin receptor polymorphisms
OtherAbstract:Palabras claves:Autores:Adrián LLerena, Dorado P., López-Torres E., Penãs-Lledó E.M., Salomón J., Vicario F.Fuentes:scopusAn Open Letter in Support of Transformative Biotechnology and Social Innovation: SANKO University Innovation Summit in Medicine and Integrative Biology, Gaziantep, Turkey, May 5-7, 2016
OtherAbstract:Palabras claves:Autores:Abou-Zeid A.H., Adrián LLerena, Akkin S.M., Aklillu E., Barlas Ö., Borda-Rodriguez A., Boschele F.A., Çetin Z., Coşkun E., Coşkun Y., Daǧli G., Dai T.U., Dandara C., Dereli T., Elbeyli L., Endrenyi L., Eyigün C.P., Georgakilas A., Günbulut B., Güngör K., Güzelbey A., Hekim C., Hekim N., Huzair F., Karakaş Ü., Kimyon S., Lin B., Masimirembwa C., McNally R., Mete A., Sancar P., Saygili E.I., Sinav A., Srivastava S., Steuten L.M.G., Tanriöver O., Töre V.I., Tyfield D., Vuruşkan D., Wang W., Warnich L., Wonkam A., Yildirim Y.Z., Yilmaz I.Fuentes:scopus