Mostrando 10 resultados de: 60
Filtros aplicados
Publisher
Pharmacogenomics(7)
Pharmacogenomics Journal(6)
European Journal of Clinical Pharmacology(5)
OMICS A Journal of Integrative Biology(4)
British Journal of Clinical Pharmacology(3)
Área temáticas
Farmacología y terapéutica(41)
Enfermedades(29)
Bioquímica(12)
Medicina y salud(12)
Fisiología humana(10)
Objetivos de Desarrollo Sostenible
ODS 3: Salud y bienestar(58)
ODS 10: Reducción de las desigualdades(33)
ODS 17: Alianzas para lograr los objetivos(16)
ODS 12: Producción y consumo responsables(11)
ODS 16: Paz, justicia e instituciones sólidas(1)
Origen
scopus(60)
A rapid and simple LC-MS/MS method for the simultaneous evaluation of CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 hydroxylation capacity
ArticleAbstract: Background: The analytical method here reported for the CEIBA cocktail approach has been developed aPalabras claves:Autores:Adrián LLerena, de Andrés F., Sosa-Macías M.G.Fuentes:scopusClinical implementation of pharmacogenetics and personalized drug prescription based on e-health: The MedeA initiative
ArticleAbstract:Palabras claves:Autores:Adrián LLerena, Cobaleda J., de Andrés F., Mata-Martín C., Penãs-Lledó E.M., Pijierro A., Sánchez C.L.Fuentes:scopusClozapine disposition covaries with CYP1A2 activity determined by a caffeine test.
ArticleAbstract: In a previous study we showed that the disposition of clozapine after a single oral dose is unrelatePalabras claves:Autores:Adrián LLerena, Alm C., Benitez Rodriguez J., Bertilsson L., Bondesson U., Carrillo J., Dahl M.L., Lindstrom L., Ramos S., Rodriguez de la Rubia I.Fuentes:scopusAssessment of the debrisoquin and dextromethorphan phenotyping tests by gaussian mixture distributions analysis
ArticleAbstract: From a sample of 149 unrelated Spaniards, individuals were phenotyped for their ability to hydroxylaPalabras claves:Autores:Adrián LLerena, Avram M., Benitez Rodriguez J., Cobaleda J., Gibbons R., Henthorn T., Krejcie T., Martinez C.Fuentes:scopusAssociation between T102C and A-1438G polymorphisms in the serotonin receptor 2A (5-HT2A) gene and schizophrenia: Relevance for treatment with antipsychotic drugs
ArticleAbstract: Background: An involvement of serotonin receptor 2A (5-HT2A) in the aetiology of schizophrenia has bPalabras claves:A-1438G polymorphism, Risperidone, Schizophrenia, Seretonin 2A receptor, T102C polymorphismAutores:Adrián LLerena, Cáceres M.C., De la Rubia A., Dorado P., Penãs-Lledó E.M.Fuentes:scopusAssociation of common genetic variants with risperidone adverse events in a Spanish schizophrenic population
ArticleAbstract: Risperidone non-compliance is often high due to undesirable side effects, whose development is in paPalabras claves:Adverse events, Antipsychotic, pharmacogenetics, RisperidoneAutores:Abad-Santos F., Adrián LLerena, Almoguera B., Ayuso C., Baca-García E., Dal-Ré R., Dorado P., Fernandez-Piqueras J., Lopez-Castroman J., Riveiro-Alvarez R., Vaquero-Lorenzo C.Fuentes:scopusBernard lerer: Recipient of the 2014 inaugural werner kalow responsible innovation prize in global omics and personalized medicine (pacific rim association for clinical pharmacogenetics)
ReviewAbstract: This article announces the recipient of the 2014 inaugural Werner Kalow Responsible Innovation PrizePalabras claves:Autores:Adrián LLerena, Aynacoǧlu S., Bragazzi N.L., Dandara C., Dove E.S., Endrenyi L., Ferguson L.R., Geraci C.J., Hafen E., Kesim B.E., Kolker E., Lee E.J.D., Nacak M., Özdemir V., Shimoda K., Someya T., Srivastava S., Tomlinson B., Vayena E., Warnich L., Yasar U.Fuentes:scopusAnalysis of diclofenac and its metabolites by high-performance liquid chromatography: Relevance of CYP2C9 genotypes in diclofenac urinary metabolic ratios
ArticleAbstract: In humans, diclofenac is metabolised to 4′-hydroxy (OH), 3′-OH and 5-OH metabolites. The polymorphicPalabras claves:CYP2C9 genotypes, Diclofenac, HydroxydiclofenacAutores:Adrián LLerena, Berecz R., Cáceres M.C., Dorado P.Fuentes:scopusAntipsychotic drugs and QTc prolongation: The potential role of CYP2D6 genetic polymorphism
ReviewAbstract: Although the most common, and usually serious, side effects of first-generation (or typical) antipsyPalabras claves:Antipsychotic drugs, Cardiac side effects, CYP2D6, drug metabolism, QT interval lengthening, Torsades de pointes-type arrhythmiaAutores:Adrián LLerena, Berecz R., Dorado P., Penãs-Lledó E.M.Fuentes:scopusCYP2D6 genotyping for psychiatric patients treated with risperidone: Considerations for cost-effectiveness studies
ArticleAbstract: In order to ascertain data availability and feasibility for conducting cost-effectiveness studies inPalabras claves:adverse drug reactions, Antipsychotic, cost-effectiveness, CYP2D6, polymorphisms, RisperidoneAutores:Adrián LLerena, De Leon J., de Mesa E.G., Gurwitz D., Ibarreta D., Kirchheiner J., Rodríguez-Antona C.Fuentes:scopus