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Drug Metabolism and Drug Interactions(2)
OMICS A Journal of Integrative Biology(2)
Current Therapeutic Research - Clinical and Experimental(1)
Enfermedades Infecciosas y Microbiologia Clinica(1)
European Journal of Clinical Pharmacology(1)
Comparison of three methods to calculate medication adherence in patients receiving antiretroviral treatment
ArticleAbstract: OBJECTIVE. Eighty-two episodes of polymicrobial bacteremia in two time periods, 1986-87 and 1996-97,Palabras claves:EVOLUTION, Polymicrobial bacteremia-fungemia, RISK FACTORSAutores:Álvarez J., Fernández M., Francisco J.López Hernández, Hernández I., La Hulla F., Méndez J., Noguerado A., Pizarro A., Ruiz-Giardín J.M., Salvanes F., San Martín J.V.Fuentes:scopusCYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population
ArticleAbstract: Purpose: Cytochrome P450 2D6 (CYP2D6) genotypes and the dextromethorphan/dextrorphan (DXM/DXT) metabPalabras claves:CYP2D6, dextromethorphan, ECUADOR, pharmacogeneticsAutores:Adrián LLerena, Dorado P., Enrique Terán, Francisco J.López Hernández, Machín E., Natalia HerasFuentes:scopusEvaluation of drug-metabolizing enzyme hydroxylation phenotypes in Hispanic populations: The CEIBA cocktail
ReviewAbstract: Interindividual differences in response to drug treatments are mainly caused by differences in drugPalabras claves:Cocktail, Cytochrome P450 (CYP), Genotype, Hispanics, PhenotypeAutores:Adrián LLerena, Alonso-Vilatela E., Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes-Garro C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Enrique Terán, Estévez-Carrizo F.E., Ferreiro V., Fiedler J., Francisco J.López Hernández, Galaviz-Hernandez C., Garza-Ocañas L., González-Vacarezza N., Grazina M., Herrera L., Jiménez-Arce G., Lares-Asseff I., Lazalde-Ramos B.P., Leonardo J. Beltrán, López-López M., Monroy-Jaramillo N., Moya G.E., Naranjo M.E.G., Natalia Heras, Ochoa-Morales A., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Rodeiro I., Rojas-Martinez A., Rojas-Ponce R., Sarmiento A.P., Sosa-Macías M.G., Tarazona-Santos E.M., Vázquez T.C., Yescas-Gómez P.Fuentes:scopusEffect of policosanol on serum lipids and lipoproteins in healthy volunteers
ArticleAbstract: Policosanol is a mixture of high molecular weight alcohols isolated from sugar cane with cholesterolPalabras claves:Autores:Castano G., Cordovi N., Fernandez J., Fernandez L., Francisco J.López Hernández, Gonzalez M., Illnait J., Mas R.Fuentes:scopusInterethnic variability in CYP2D6, CYP2C9, and CYP2C19 genes and pbkp_redicted drug metabolism phenotypes among 6060 ibero-and native Americans: RIBEF-CEIBA consortium report on population pharmacogenomics
ArticleAbstract: Pharmacogenetic variation in Latin Americans is understudied, which sets a barrier for the goal of gPalabras claves:Amerindians, CYP2C19, CYP2C9, CYP2D6, drug metabolism, LATIN AMERICANS, pharmacogenetics, Precision MedicineAutores:Adrián LLerena, Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes-Garro C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Enrique Terán, Estévez-Carrizo F.E., Fcrreiro V., Francisco J.López Hernández, Fricke-Galindo I., Galaviz-Hernandez C., Garza-Ocañas L., Gilman R.H., Gouveia M.H., Grazina M., Humberto Fariñas, Jiménez-Arce G., Jung-Cook H., Lares-Aseff I., Lazalde-Ramos B.P., López-López M., Monroy-Jaramillo N., Moya G.E., Naranjo M.E.G., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Rodeiro I., Rodrigues-Soares F., Rojas-Martinez A., Santiago Terán, Sarmiento A.P., Scliar M.O., Sosa-Macías M.G., Tarazona-Santos E.M., Tinoco C.A., Zamudio R.Fuentes:googlescopusPharmacogenetics and ethnicity: relevance for clinical implementation, clinical trials, pharmacovigilance and drug regulation in Latin America
Conference ObjectAbstract: Congress of Pharmacogenetics and Personalized Medicine. Ethnicity, clinical implementation and regulPalabras claves:clinical trials, Latin American populations, metabolic genotypes, Metabolic phenotypes, native populations, pharmacogenetics, pharmacovigilanceAutores:Adrián LLerena, Altamirano C., Céspedes-Garro C., Enrique Terán, Francisco J.López Hernández, Galaviz-Hernandez C., Humberto Fariñas, Jung-Cook H., López-López M., MARTHA FORS, Martha M. Fors-López, Moya G.E., Ramirez R., Remírez D., Sosa-Macías M.G., Tarazona-Santos E.M., William F. WatersFuentes:googlescopusPharmacogenetics in Latin American populations: Regulatory aspects, application to herbal medicine, cardiovascular and psychiatric disorders
Conference ObjectAbstract: Meeting report of the " Second Symposium on Pharmacology of Cytochrome P450 and Transporters " organPalabras claves:Cytochrome p450, Hispanics, Latin America, pharmacogeneticsAutores:Adrián LLerena, Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Doredo P., ElisaAlonso M., Enrique Terán, Estévez-Carrizo F.E., Ferrero V., Fiedler J., Francisco J.López Hernández, Galaviz-Hernandez C., García-Mesa M., Garza-Ocañas L., González-Naranjo M.E., González-Vacarezza N., Grazina M., Herrera L., Jiménez-Arce G., Lares-Asseff I., Lazalde B., Leonardo J. Beltrán, López-López M., Monroy-Jaramillo N., Moya G.E., Natalia Heras, Ochoa-Morales A., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Remírez-Figueredo D., Rodeiro I., Rojas-Martinez A., Rojas-Ponce R., Sarmiento-Sánchez A.P., Sosa-Macías M.G., Tarazona-Santos E.M., Vázquez T.C., Yescas-Gómez P.Fuentes:scopusPopulation pharmacokinetics of digoxin in pediatric patients
ArticleAbstract: Digoxin pharmacokinetics were studied in a pediatric population with an age range of 6 days to 1 yeaPalabras claves:Digoxin, pediatric patients, Population pharmacokineticsAutores:Arranz I., Falcao A.C., Francisco J.López Hernández, González M.C., Lanao J.M., Martín-Suárez A., Outeda M., Quero M.Fuentes:scopusTo Genotype or Phenotype for Personalized Medicine? CYP450 Drug Metabolizing Enzyme Genotype-Phenotype Concordance and Discordance in the Ecuadorian Population
ArticleAbstract: Genetic variations within the cytochrome P450 (CYP450) superfamily of drug metabolizing enzymes confPalabras claves:Biomarkers, developing world omics, Diagnostic Medicine, Innovation Systems, personalized medicine, Systems DiagnosticsAutores:Adrián LLerena, de Andrés F., Enrique Terán, Francisco J.López Hernández, Santiago TeránFuentes:googlescopus