Mostrando 4 resultados de: 4
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Pharmacogenomics(2)
Drug Metabolism and Personalized Therapy(1)
Expert Opinion on Drug Metabolism and Toxicology(1)
Interethnic variability of CYP2D6 alleles and of pbkp_redicted and measured metabolic phenotypes across world populations
ReviewAbstract: Introduction: The frequency of CYP2D6 alleles, related to either a lack of or increased enzymatic acPalabras claves:CYP2D6, CYP2D6∗10, CYP2D6∗17, CYP2D6∗29, CYP2D6∗4, CYP2D6∗41, ethnicity, Poor metabolizers, population pharmacogenetics, Ultrarapid metabolizersAutores:Adrián LLerena, Humberto Fariñas, Naranjo M.E.G., Penãs-Lledó E.M., Rodrigues-Soares F., Tarazona-Santos E.M.Fuentes:scopusPharmacogenetic research activity in Central America and the Caribbean: A systematic review
ReviewAbstract: Aim: The present review was aimed at analyzing the pharmacogenetic scientific activity in Central AmPalabras claves:Biomarkers, Caribbean Region, Central America, pharmacogenetics, PharmacogenomicsAutores:Adrián LLerena, Campos M.D.L.A., Céspedes-Garro C., Duconge J., Humberto Fariñas, Montané-Jaime L.K., Naranjo M.E.G., Penãs-Lledó E.M., Ramirez R., Roblejo H., Rodrigues-Soares F., Serrano V., Villagrán C.I.Fuentes:scopusPharmacogenetics and ethnicity: relevance for clinical implementation, clinical trials, pharmacovigilance and drug regulation in Latin America
Conference ObjectAbstract: Congress of Pharmacogenetics and Personalized Medicine. Ethnicity, clinical implementation and regulPalabras claves:clinical trials, Latin American populations, metabolic genotypes, Metabolic phenotypes, native populations, pharmacogenetics, pharmacovigilanceAutores:Adrián LLerena, Altamirano C., Céspedes-Garro C., Enrique Terán, Francisco J.López Hernández, Galaviz-Hernandez C., Humberto Fariñas, Jung-Cook H., López-López M., MARTHA FORS, Martha M. Fors-López, Moya G.E., Ramirez R., Remírez D., Sosa-Macías M.G., Tarazona-Santos E.M., William F. WatersFuentes:googlescopusPharmacogenetics in Central American healthy volunteers: Interethnic variability
ReviewAbstract: Ethnicity is one of the major factors involved in interindividual variability to drug response. ThisPalabras claves:Admixed, Afro-Caribbean, Amerindian, Biomarkers, Central America, CYP1A2, CYP2C19, CYP2D6, CYP2E1, G6PD, HLA, LDLR, MDR1, NAT2, pharmacogenetics, TP53Autores:Adrián LLerena, Barrantes R., Céspedes-Garro C., Humberto Fariñas, Naranjo M.E.G., Ramirez R., Serrano V.Fuentes:scopus