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google(16)
Asthma exacerbations and inhaled corticosteroids
OtherAbstract: Sir—TW Harrison and colleagues (Jan 24, p 271) 1 examine the effects of doubling the dose of inhaledPalabras claves:Autores:Harrison CastroFuentes:googleA Randomized Trial of a Composite T2-Biomarker Strategy Adjusting Corticosteroid Treatment in Severe Asthma: A Post Hoc Analysis by Sex
OtherAbstract: Background Approximately 5% to 10% of patients with asthma have severe disease, with a consistent prPalabras claves:Autores:Harrison CastroFuentes:googleA comparative assessment of γ-secretase activity in transgenic and non-transgenic rodent brain
OtherAbstract: Amyloid-beta (Aβ) deposits are one of the hallmarks of the neuropathological degeneration observed iPalabras claves:Autores:Harrison CastroFuentes:googleElimination of oral corticosteroids (OCS) with benralizumab treatment in OCS-dependent asthmatics using a rapid, personalized algorithm: the PONENTE trial
OtherAbstract: Methods This single-arm study of 598 patients assessed the efficacy and safety of daily OCS dosage rPalabras claves:Autores:Harrison CastroFuentes:googleEffect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre …
OtherAbstract: Background The role of interleukin 13 in airway inflammation and remodelling in asthma is unclear. TPalabras claves:Autores:Harrison CastroFuentes:googleOnset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma …
OtherAbstract: Background ANDHI was done to assess the efficacy of benralizumab, including onset of effect and impaPalabras claves:Autores:Harrison CastroFuentes:googleOral corticosteroid elimination via a personalised reduction algorithm in adults with severe, eosinophilic asthma treated with benralizumab (PONENTE): a multicentre, open-label …
OtherAbstract: Background No consensus exists on how to reduce oral corticosteroids after the initiation of biologiPalabras claves:Autores:Harrison CastroFuentes:googlePRS68 The Humanistic Burden of Mild Asthma: Evidence from the Novelty Study
OtherAbstract: BACKGROUND: There is limited evidence on health-related quality of life (HRQOL) among patients withPalabras claves:Autores:Harrison CastroFuentes:googleIntra-or intercomplex binding to the γ-secretase enzyme: a model to differentiate inhibitor classes
OtherAbstract: γ-Secretase is one of the critical enzymes required for the generation of amyloid-β peptides from thPalabras claves:Autores:Harrison CastroFuentes:googlePharmacological knock-down of the presenilin 1 heterodimer by a novel γ-secretase inhibitor: implications for presenilin biology
OtherAbstract: Intramembranous cleavage of the β-amyloid precursor protein by γ-secretase is the final processing ePalabras claves:Autores:Harrison CastroFuentes:google