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Forensic Science International: Genetics Supplement Series(2)
American Journal of the Medical Sciences(1)
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Frontiers in Pharmacology(1)
Integrated In Silico Analyses Identify PUF60 and SF3A3 as New Spliceosome-Related Breast Cancer RNA-Binding Proteins
ArticleAbstract: More women are diagnosed with breast cancer (BC) than any other type of cancer. Although large-scalePalabras claves:Breast Cancer, cancer driver genes, in silico analysis, RBPsAutores:Andrea Jácome-Alvarado, Andrés López-Cortés, Andy Pérez-Villa, INDACOCHEA A., Isaac Armendáriz-Castillo, Jennyfer García, Jennyfer M. García-Cárdenas, Santiago Xavier GuerreroFuentes:googlescopusScreening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease
ArticleAbstract: Early-onset Alzheimer's disease (EOAD) can be familial (FAD) or sporadic EOAD (sEOAD); both have a dPalabras claves:Alzheimer's disease, APP, Early-onset, Rs367709245, screening, SporadicAutores:Barber I.S., Braae A., Bras J., Brookes K., Chappell S., Clement N., Craig D., Deacon C., Guerreiro R., Guetta-Baranes T., Harris J., Hernandez D., Heun R., Holmes C., Hooper N.M., Jennyfer García, Jennyfer M. García-Cárdenas, Johnston J., Jones M., Kehoe P.G., Kolsch H., Lowe J., Mann D.M., McGuinness B., Medway C., Morgan K., Neary D., Passmore P., Patel T., Pickering-Brown S., Richardson A., Sakdapanichkul C., Singleton A., Smith A.D., Snowden J., Todd S., Vardy E.R.L.C., Warden D., Wilcock G., Zapata Erazo G.Fuentes:googlescopusPositive association of the cathepsin D Ala224Val Gene polymorphism with the risk of Alzheimer's disease
ArticleAbstract: Background: Alzheimer's disease (AD) is the most common cause of senile dementia. In Ecuador, the nuPalabras claves:Alzheimer's disease, Capillary sequencing, Genetic PolymorphismsAutores:Andrés López-Cortés, Carolina Salazar, Cesar Paz-y-Miño, Jennyfer M. García-Cárdenas, Paola E. Leone, Serrano Dueñas MarcosFuentes:scopusEvaluation of ancestral membership proportions and genotype distribution in the perception of Umami taste in Ecuadorian mestizos
ArticleAbstract: Genetic variation to flavor perception contributes the population differentiation, where the T allelPalabras claves:ECUADOR, Taste perception, UmamiAutores:Alejandro Cabrera-Andrade, Alexandra Patricia Guevara, Ana Karina Zambrano , Andrés López-Cortés, Cesar Paz-y-Miño, D. A. González, Jennyfer García, Jennyfer M. García-Cárdenas, Paola E. LeoneFuentes:googlescopusIn silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19
ArticleAbstract: Background: There is pressing urgency to identify therapeutic targets and drugs that allow treatingPalabras claves:artificial neural networks, covid-19, drug repurposing, Immune system, single-cell RNA sequencingAutores:Adriana Granizo-Martínez, Alejandro Cabrera-Andrade, Alexandra Patricia Guevara, Ana Karina Zambrano , Ana María Gómez-Jaramillo, Andreina Quevedo, Andrés López-Cortés, Ángela León-Cáceres, Carlos Barba-Ostria, Cesar Paz-y-Miño, Cevallos-Robalino D., Eduardo Tejera, Esteban Ortiz-Prado, Jennyfer M. García-Cárdenas, Jhommara Bautista, Katherine Simbaña-Rivera, Lourdes Puig San Andrés, Moreno S., Munteanu C.R., Nikolaos C. Kyriakidis, Pérez-M G., Proaño-Castro C., Quiñones L.A., Santiago Xavier Guerrero, Varela N.M., Yunierkis Perez-CastilloFuentes:scopusThe close interaction between hypoxia-related proteins and metastasis in pancarcinomas
ArticleAbstract: Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access to nutriePalabras claves:Autores:Alexandra Patricia Guevara, Andrea Abad-Sojos, Andrés López-Cortés, Andy Pérez-Villa, Ángela León-Cáceres, Antonella Vera-Guapi, Echeverría-Garcés G., Esteban Ortiz-Prado, Isaac Armendáriz-Castillo, Jennyfer García, Jennyfer M. García-Cárdenas, Jhommara Bautista, Katherine Simbaña-Rivera, Lourdes Puig San Andrés, Nikolaos C. Kyriakidis, Prathap L., Santiago Xavier Guerrero, Varela N.M., Verónica YumicebaFuentes:googlescopusGenes involved in damage response caused by UV radiation in Ecuadorian population of different altitude regions
ArticleAbstract: Ecuador has various regions at different altitudes. It is known that at high altitudes, organisms exPalabras claves:altitude, ECUADOR, UV radiation, XPC, XPD, XPGAutores:Alexandra Patricia Guevara, Ana Karina Zambrano , Andrés López-Cortés, Andy Pérez-Villa, Cesar Paz-y-Miño, Isaac Armendáriz-Castillo, Jennyfer García, Jennyfer M. García-Cárdenas, Paola E. Leone, Santiago Xavier Guerrero, Verónica YumicebaFuentes:googlescopusCharacterization of Ancestral Origin of Cystic Fibrosis of Patients with New Reported Mutations in CFTR
ArticleAbstract: The incidence of cystic fibrosis (CF) and the frequency of the variants reported for CFTR depend onPalabras claves:Autores:Alexandra Patricia Guevara, Ana Karina Zambrano , Andrés López-Cortés, Andy Pérez-Villa, Cesar Paz-y-Miño, Isaac Armendáriz-Castillo, Jennyfer García, Jennyfer M. García-Cárdenas, Juan Carlos Ruiz-Cabezas, Paola E. Leone, Santiago Xavier Guerrero, Verónica YumicebaFuentes:googlescopusTcga pan-cancer genomic analysis of alternative lengthening of telomeres (Alt) related genes
ArticleAbstract: Telomere maintenance mechanisms (TMM) are used by cancer cells to avoid apoptosis, 85–90% reactivatePalabras claves:ALT, Cáncer, IN SILICO, TelomeresAutores:Alexandra Patricia Guevara, Ana Karina Zambrano , Andrés López-Cortés, Andy Pérez-Villa, Cesar Paz-y-Miño, Isaac Armendáriz-Castillo, Jennyfer M. García-Cárdenas, Paola E. Leone, Santiago Xavier Guerrero, Verónica YumicebaFuentes:scopus