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A Conserved uORF Regulates APOBEC3G Translation and Is Targeted by HIV-1 Vif Protein to Repress the Antiviral Factor
ArticleAbstract: The HIV-1 Vif protein is essential for viral fitness and pathogenicity. Vif decreases expression ofPalabras claves:APOBEC3G, HIV-1, mRNA, translation, UORF, VifAutores:Batisse J., Cabrera-Rodriguez R., Cimarelli A., Etienne L., Gilmer O., Libre C., Marquet R., Paillart J.C., Santiago Xavier Guerrero, Seissler T., Stupfler B., Valenzuela-Fernandez A., Verriez C., Weber M.M.Fuentes:googlescopusA transcription factor acts as a HIV-1 accomplice to destroy the cellular defences
ArticleAbstract:Palabras claves:Autores:Batisse J., Bernacchi S., Marquet R., Paillart J.C., Pernot S., Santiago Xavier GuerreroFuentes:googlescopusIn silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19
ArticleAbstract: Background: There is pressing urgency to identify therapeutic targets and drugs that allow treatingPalabras claves:artificial neural networks, covid-19, drug repurposing, Immune system, single-cell RNA sequencingAutores:Adriana Granizo-Martínez, Alejandro Cabrera-Andrade, Ana Karina Zambrano, Ana María Gómez-Jaramillo, Andreina Quevedo, Andrés López-Cortés, Ángela León-Cáceres, Carlos Barba-Ostria, Cesar Paz-y-Miño, Cevallos-Robalino D., Eduardo Tejera, Esteban Ortiz-Prado, Jennyfer M. García-Cárdenas, Jhommara Bautista, Katherine Simbaña-Rivera, Lourdes Puig San Andrés, Moreno S., Munteanu C.R., Nikolaos C. Kyriakidis, P. Guevara-Ramírez, Pérez-M G., Proaño-Castro C., Quiñones L.A., Santiago Xavier Guerrero, Varela N.M., Yunierkis Perez-CastilloFuentes:scopusPulmonary Inflammatory Response in Lethal COVID-19 Reveals Potential Therapeutic Targets and Drugs in Phases III/IV Clinical Trials
ArticleAbstract: Background: It is imperative to identify drugs that allow treating symptoms of severe COVID-19. RespPalabras claves:clinical trials, drugs, lethal COVID-19, pulmonary inflammatory response, single nucleus RNA sequencingAutores:Alejandro Cabrera-Andrade, Álvaro A. Pérez-Meza, Ana María Gómez-Jaramillo, Andrea Abad-Sojos, Andrea V. Jácome, Andrés López-Cortés, Andy Pérez-Villa, Ángela León-Cáceres, Antonella Vera-Guapi, Ariana León-Sosa, Cevallos-Robalino D., Echeverría-Garcés G., Esteban Ortiz-Prado, Estefanía Abarca, Fernanda Arias-Erazo, Isaac Armendáriz-Castillo, Jennyfer M. García-Cárdenas, Jhommara Bautista, Katherine Simbaña-Rivera, Lourdes Puig San Andrés, Luis Fuenmayor-González, Morillo A., Nieto-Jaramillo K., Nikolaos C. Kyriakidis, P. Guevara-Ramírez, Quiñones L.A., Ramos-Medina M.J., Santiago Xavier Guerrero, Verónica YumicebaFuentes:scopus