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Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers
ArticleAbstract: Apoptosis inducers represent an attractive approach for the discovery and development of anticancerPalabras claves:apoptosis, Compound library, Cytotoxicity, Structure-activity relationship, Withaferin AAutores:Bazzocchi I.L., Jiménez C., Jiménez I.A., Liliana Araujo-Baptista, Llanos G.G., Moujir L.M., Rodríguez J.Fuentes:scopusWithaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells
ArticleAbstract: Six new withanolides (1-6) along with eleven known ones (7-17) were isolated from the leaves of WithPalabras claves:Antiproliferative, apoptosis, Caspase-3, Human cancer cell lines, Structure-activity relationship, Withania aristata, WithanolidesAutores:Bazzocchi I.L., Jiménez I.A., Liliana Araujo-Baptista, Llanos G.G., Moujir L.M.Fuentes:scopus