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Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells
ArticleAbstract: Imatinib induces a complete cytogenetic regression in a large percentage of patients affected by chrPalabras claves:apoptosis, Autophagy, Chronic myeloid leukemia, Imatinib mesylate, PI3K inhibitor, Src kinase inhibitorAutores:Boffo S., Caparrotti G., Ciarcia R., D'Angelo D., Damiano S., Fátima Morales, Florio S., Giordano A., Montagnaro S., Pagnini U., Rizzolio F., Ruocco A.Fuentes:scopusAnti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)- 9H- or 7H-purines against several human solid tumour cell lines
ArticleAbstract: As leads we took several benzo-fused seven- and six-membered scaffolds linked to the pyrimidine or pPalabras claves:5-Fluorouracil, Anti-tumour compounds, apoptosis, Breast Cancer, Colon cancer, melanoma, purinesAutores:Campos J.M., Conejo-García A., Fátima Morales, Marchal J.A., Morata-Tarifa C., Ramírez A.Fuentes:scopusAntitumoral activity of 1,2-diaminocyclohexane derivatives in breast, colon and skin human cancer cells
ArticleAbstract: Aim: Cancer is among the leading causes of death worldwide. Medical interest has focused on macrocycPalabras claves:1,2-diaminocyclohexanes, antitumor, apoptosis, benzenesulfonamides, Breast Cancer, Caspases, Colon cancer, Macrocycles, melanomaAutores:Campos J.M., Conejo-García A., Fátima Morales, Marchal J.A., Morata-Tarifa C., Navarro S.A., Ramírez A.Fuentes:scopus