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A multicomponent pharmacophore fragment-decoration approach to identify selective LRRK2-targeting probes
ArticleAbstract: Herein we report the development of a new versatile chemical tool for the rapid identification of LRPalabras claves:Autores:Castagnolo D., Costantino G., Crespan E., Giagnorio F., Jorge I. Armijos-Rivera, Kissova M., Maga G., Radi M., Scalacci N., Tassini S.Fuentes:googlescopusFeeding ecology of the Andean fox in southern Ecuador: Wild ungulates being the main prey
ArticleAbstract: This study details for the first time the food habits of the culpeo or Andean fox (Lycalopex culpaeuPalabras claves:Andes, Canids, Carnivores, cloud forest, diet, Paramo, Podocarpus, Trophic diversityAutores:Carlos Narváez, Jorge I. Armijos-Rivera, Jorge Lozano, Marta Guntiñas, Rodrigo Cisneros VidalFuentes:scopusEffect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3 H)-ones
ArticleAbstract: Conformational restriction applied to dihydrobenzylpyrimidin-4-(3H)-ones (DABOs) by the intoductionPalabras claves:Autores:Badia R., Cirilli R., Crespan E., Esté J.A., Forgione M., Hailu G., Jorge I. Armijos-Rivera, Kirillov I., Lucidi A., Maga G., Mai A., Nawrozkij M., Panella C., Patsilinakos A., Ragno R., Riveira-Munoz E., Rotili D., Tomaselli D., Yablokov A.Fuentes:googlescopusDiscovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases
ArticleAbstract: Enteroviruses (EVs) are among the most frequent infectious agents in humans worldwide and representPalabras claves:Autores:Cavalli A., Costantino G., Crespan E., Delang L., Falchi F., Jorge I. Armijos-Rivera, Kissova M., Langron E., Lanko K., Leyssen P., Maga G., Mirabelli C., Neyts J., Pieroni M., Radi M., Sun L., Tassini S., Vergani P.Fuentes:googlescopusNew indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains
ArticleAbstract: We designed and synthesized 21 new indolylarylsulfones (IASs) as new HIV-1 NNRTIs. Among these, IASPalabras claves:AIDs, HIV-1, Indolylarylsulfone, Non-nucleoside reverse transcriptase inhibitor, Reverse transcriptaseAutores:Badia R., Brambilla A., Catalano M., Cinquina E., Coluccia A., Crespan E., Esté J.A., Falasca F., Jorge I. Armijos-Rivera, La Regina G., Limatola C., Maga G., Masci D., Nalli M., Riveira-Munoz E., Silvestri R., Turriziani O.Fuentes:scopusIdentification of Broad-Spectrum Dengue/Zika Virus Replication Inhibitors by Functionalization of Quinoline and 2,6-Diaminopurine Scaffolds
ArticleAbstract: Social and demographic changes across the world over the past 50 years have resulted in significantPalabras claves:2,6-diaminopurines, broad-spectrum antivirals, co-infections, DENGUE, zikaAutores:Costantino G., Crespan E., Jorge I. Armijos-Rivera, Kaptein S., Maga G., Neyts J., Radi M., Vincetti P.Fuentes:scopus