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(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
ArticleAbstract: Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of AlzPalabras claves:acetylcholinesterase inhibitors, Cerebellar granule cells, colchicine, neuronal death, RATAutores:Antoni Camins, Camps P., Canudas A.M., Jiménez A., Jordá E.G., Muñoz-Torrero D., Pallás M., Rimbau V., Verdaguer E.Fuentes:scopus3,4-Methylenedioxymethamphetamine enhances kainic acid convulsive susceptibility
ArticleAbstract: Kainic acid (KA) causes seizures and neuronal loss in the hippocampus. The present study investigatePalabras claves:Calbindin, Calretinin, Kainic acid, MDMA, Parvalbumin, seizuresAutores:Abad S., Antoni Camins, Auladell C., Camarasa J., Escubedo E., Junyent F., Pallás M., Pubill D.Fuentes:scopus3-Amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons
ArticleAbstract: The mechanisms underlying selective neuronal cell death in kainic acid-mediated neurodegeneration arPalabras claves:cell cycle, Cyclin-dependent kinases, Excitotoxicity, Neurodegenerative illnessAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopus3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum
ArticleAbstract: 3-Nitropropionic acid (3-NP) is a neurotoxin that inhibits mitochondrial complex II and is used in aPalabras claves:3-nitropropionic acid, Calpain, CDK5, MEF2Autores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusA chronological review of potential disease-modifying therapeutic strategies for Alzheimer's disease
ReviewAbstract: Late-onset Alzheimer’s disease (LOAD) is a neurodegenerative disorder that has become a worldwide hePalabras claves:Alzheimer’s disease, calcium, ER stress, glutamate, Neurodegeneration, neuroinflammation, Oxidative Stress, Parkinson’s DiseaseAutores:Antoni Camins, Auladell C., Busquets O., Espinosa-Jimenez T., Ettcheto M., Verdaguer E.Fuentes:scopusA flow cytometric study of N-methyl-D-aspartate effects on dissociated cerebellar cells
ArticleAbstract: The effects of N-methyl-D-aspartate (NMDA) on the generation of intracellular reactive oxygen speciePalabras claves:calcium, Cerebellum, Flow cytometry, granule cell, Indo-1, MK-801, NMDA, Oxidative StressAutores:Antoni Camins, Camarasa J., Escubedo E., Sureda F.X., Trullàs R.Fuentes:scopusA single dose of pirfenidone attenuates neuronal loss and reduces lipid peroxidation after kainic acid-induced excitotoxicity in the pubescent rat hippocampus
ArticleAbstract: Systemic administration of kainic acid (KA) in rodents triggers limbic seizures following selectivePalabras claves:4-Hydroxynonenal (4-HNE), Kainic Acid Model, Neurodegeneration, neuroprotection, PirfenidoneAutores:Antoni Camins, Armendáriz-Borunda J., Bañuelos-Pineda J., Castro-Torres R.D., Chaparro-Huerta V., Flores-Soto M.E., Orozco-Suárez S.A., Zárate C.B.Fuentes:scopusChanges in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8
ArticleAbstract: The senescence-accelerated strains of mice (SAMP) are well-characterized animal models of senescencePalabras claves:Calpain, Catalase, Neurodegeneration, Oxidative Stress, Senescence, TauAutores:Antoni Camins, Canudas A.M., Gutiérrez-Cuesta J., Mallol J., Mulero M., Pallás M., Romeu M., Sureda F.X.Fuentes:scopusCharacterization of amyloid-β granules in the hippocampus of SAMP8 mice
ArticleAbstract: The senescence accelerated mouse-prone 8 (SAMP8) strain of mice is an experimental model of acceleraPalabras claves:Alzheimer's disease, Amyloid-β, hippocampus, HSPG, MAP-2, SAMP8, syndecan, TauAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Mercader C., Pallás M., Vilaplana J.Fuentes:scopusChronic administration of melatonin reduces cerebral injury biomarkers in SAMP8
ArticleAbstract: Certain effects of melatonin on senescence were investigated. The experimental model used was 10-monPalabras claves:aging, ck5/p35, GSK3β, Oxidative Stress, SAMP8, TauAutores:Antoni Camins, Caballero B., Canudas A.M., Coto-Montes A., Gutiérrez-Cuesta J., Pallás M., Romeu M., Sureda F.X.Fuentes:scopus