Mostrando 10 resultados de: 27
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Journal of Pineal Research(6)
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scopus(27)
Chronic administration of melatonin reduces cerebral injury biomarkers in SAMP8
ArticleAbstract: Certain effects of melatonin on senescence were investigated. The experimental model used was 10-monPalabras claves:aging, ck5/p35, GSK3β, Oxidative Stress, SAMP8, TauAutores:Antoni Camins, Caballero B., Canudas A.M., Coto-Montes A., Gutiérrez-Cuesta J., Pallás M., Romeu M., Sureda F.X.Fuentes:scopusClustered granules present in the hippocampus of aged mice result from a degenerative process affecting astrocytes and their surrounding neuropil
ArticleAbstract: Clusters of pathological granular structures appear and progressively increase in number with age inPalabras claves:aging, Astrocyte, Granules, hippocampus, Neo-epitope, Periodic acid-Schiff, SAMP8Autores:Antoni Camins, Cabezón I., Liberski P.P., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusAn evaluation of the neuroprotective effects of melatonin in an in vitro experimental model of age-induced neuronal apoptosis
ArticleAbstract: The neuroprotective effects of melatonin in an experimental model of aging-induced apoptosis have bePalabras claves:aging, cell cycle, Neurodegeneration, P53Autores:Antoni Camins, Pallás M., Pelegrí Gabalda C., Tajes Orduña M., Vilaplana J.Fuentes:scopusAnti-aging properties of melatonin in an in vitro murine senescence model: Involvement of the sirtuin 1 pathway
ArticleAbstract: Sirtuin 1 is a member of the sirtuin family of protein deacetylases, which have attracted considerabPalabras claves:ADAM10, aging, Neurodegeneration, NFκB, Oxidative Stress, P53Autores:Antoni Camins, Gutiérrez-Cuesta J., Ortuo-Sahagún D., Pallás M., Tajes M.Fuentes:scopusActivation of Akt by lithium: Pro-survival pathways in aging
ArticleAbstract: The effects of lithium on senescence were investigated using the senescence-accelerated mouse pronePalabras claves:aging, Lithium chloride, Neurodegeneration, neuroprotection, SAMP8Autores:Antoni Camins, Casadesús G., Chou S.P., Pallás M., Smith M.A., Tajes M., Yeste-Velasco M., Zhu X.Fuentes:scopusAge-related expression of adenosine receptors in brain from the senescence-accelerated mouse
ArticleAbstract: Senescence-accelerated mice (SAM) are used as a model of aging and age-associated diseases. SAMP8 arPalabras claves:Adenosine receptors, aging, BRAIN, Radioligand binding, Senescence-accelerated mouseAutores:Albasanz J.L., Antoni Camins, Castillo C.A., Jordan J., León D., Martín M., Pallás M.Fuentes:scopusAmyloid and tau pathology of familial Alzheimer’s disease APP/PS1 mouse model in a senescence phenotype background (SAMP8)
ArticleAbstract: The amyloid precursor protein/presenilin 1 (APP/PS1) mouse model of Alzheimer’s disease (AD) has proPalabras claves:aging, cognitive impairment, Familial Alzheimer’s disease (fAD), Tau hyperphosphorylation, β-AmyloidAutores:Andrés-Benito P., Antoni Camins, Canudas A.M., Del Valle J., Ferrer I., Griñan-Ferré C., Pallás M., Porquet D.Fuentes:scopusDepression-like behavior is dependent on age in male SAMP8 mice
ArticleAbstract: Aging is associated with an increased risk of depression in humans. To elucidate the underlying mechPalabras claves:aging, Depression, Dexamethasone suppression test, Forced swimming test, SAMP8Autores:Antoni Camins, Camarasa J., Ciudad-Roberts A., Escubedo E., Pallás M., Pérez-Cáceres D., Pubill D., Rodrigo M.T.Fuentes:scopusEarly amyloid accumulation in the hippocampus of SAMP8 mice
ArticleAbstract: Late-onset Alzheimer's disease (AD) is the most common form of AD appearing after 65 years of age. TPalabras claves:aging, Alzheimer's disease, Amyloid-β, Aβ40, Aβ42, AβPP, hippocampus, SAMP8, SAMR1, SenescenceAutores:Antoni Camins, Casadesús G., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopusDownregulation of canonical Wnt signaling in hippocampus of SAMP8 mice
ArticleAbstract: In the adult brain, canonical Wnt (Wnt/β-catenin) signaling modulates neuronal function, hippocampalPalabras claves:aging, Alzheimer's disease, DKK-1, hippocampus, SAMP8, Wnt, β-cateninAutores:Andrés P., Antoni Camins, Bayod S., Canudas A.M., Felice P., Pallás M., Rosa P.Fuentes:scopus