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A novel variant in CDKN1C is associated with intrauterine growth restriction, short stature, and early-adulthood-onset diabetes
ArticleAbstract: Design, Setting, and Participants: Genomic DNA samples (15 affected and 26 unaffected from a six-genPalabras claves:Autores:Andres Zurita, Andrew S., Carolina Guevara, Dauber A., Geng J., Guo M., Hwa V., Jaime Guevara-Aguirre, Kerns S.L., Marco Guevara-Aguirre, Oddoux C., Ostrer H., Rosenfeld R.G., Shen Y.Fuentes:scopusA randomized, double blind, placebo-controlled trial on safety and efficacy of recombinant human insulin-like growth factor-I in children with growth hormone receptor deficiency
ArticleAbstract: GH insensitivity due to GH receptor deficiency is a rare autosomal recessive condition, characterizePalabras claves:Autores:Diamond F.B., Gargosky S.E., Jaime Guevara-Aguirre, Martinez L., Martinez V., Nonoshita L., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusAssessing insulin sensitivity and resistance in syndromes of severe short stature
ArticleAbstract: Individuals affected with two genetic syndromes identified in Ecuador have severe short stature andPalabras claves:Homeostatic minimal models, Insulin Resistance, Metabolic phenotypeAutores:Antonio Wenceslao Danilo Gavilanes, Carolina Guevara, Daniela Lescano, Enrique Terán, Guevara A., Jaime Guevara-Aguirre, Procel P., Saavedra J., Wasserfall C.H.Fuentes:scopusBeneficial Effects of Addition of Oral Spray Insulin (Oralin) on Insulin Secretion and Metabolic Control in Subjects with Type 2 Diabetes Mellitus Suboptimally Controlled on Oral Hypoglycemic Agents
ArticleAbstract: The aim of this study was to determine the metabolic effect and the safety of a novel oral insulin sPalabras claves:Autores:Guevara M., Jaime Guevara-Aguirre, Mihic M., Modi P., Saavedra J.Fuentes:scopusBone mineral, histomorphometry, and body composition in adults with growth hormone receptor deficiency
ArticleAbstract: Growth hormone (GH) and insulin-like growth factor I (IGF-I) deficiencies have been associated withPalabras claves:Autores:Bachrach L.K., Jaime Guevara-Aguirre, Marcus R., Martinez A.L., Martinez V., Ott S.M., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusGH receptor deficiency in ecuadorian adults is associated with obesity and enhanced insulin sensitivity
Conference ObjectAbstract: Context: Ecuadorian subjects with GH receptor deficiency (GHRD) have not developed diabetes, despitePalabras claves:Autores:Alfaras I., Balasubramanian P., Carolina Guevara, De Cabo R., Di Biase S., Enrique Terán, Jaime Guevara-Aguirre, Longo V.D., Marco Guevara-Aguirre, Narvaez L., Procel P., Rosenbloom A.L., Saavedra J.Fuentes:googlescopusNormal intelligence with severe insulin-like growth factor I deficiency due to growth hormone receptor deficiency: A controlled study in a genetically homogeneous population
ArticleAbstract: Superior school performance was reported for 52 Ecuadorian probands with severe deficiency of insuliPalabras claves:Autores:Jaime Guevara-Aguirre, Kranzler J., Martinez V., Rosenbloom A.L.Fuentes:scopusTwo-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: Comparison of two dosage levels and to GH-treated GH deficiency
ArticleAbstract: We have reported 1-yr results of a double blind, placebo-controlled trial of recombinant human insulPalabras claves:Autores:Allen L., Gargosky S.E., Jaime Guevara-Aguirre, Martinez V., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusSerum levels of insulin-like growth factor binding proteins in Ecuadorean children with growth hormone insensitivity
Conference ObjectAbstract: Although insulin-like growth factor binding proteins (IGFBPs) are known to be important modulators oPalabras claves:Growth hormone, Growth hormone insensitivity, Insulin-like growth factor binding protein, Insulin-like growth factor IAutores:Burren C.P., Cohen P., Jaime Guevara-Aguirre, Mohan S., Rosenfeld R.G., Wanek D.Fuentes:scopusSex differences in clinical trials of ALRV5XR treatment of androgenetic alopecia and telogen effluvium
ArticleAbstract: Introduction: ALRV5XR treatment of androgenetic alopecia (AGA) and telogen effluvium (TE) has earlyPalabras claves:ALRV5XR, Androgenetic alopecia, hair regrowth dynamics, hair restoration, miniaturization reversal, pattern hair loss, regenerative medicine, telogen effluviumAutores:Feldman O.J., Feldman P.R., Fiebig K.M., Jaime Guevara-AguirreFuentes:scopus