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Acta Pædiatrica(4)
Acta Paediatrica, International Journal of Paediatrics, Supplement(2)
Growth Hormone and IGF Research(2)
American Journal of Medical Genetics, Part A(1)
Journal of Neuroscience(1)
Body changes in adolescent patients with growth hormone receptor deficiency receiving recombinant human insulin‐like growth factor I and luteinizing hormone‐releasing hormone analogue: preliminary results
ArticleAbstract: Auxological and body composition changes were studied in three adolescent patients (2 female, 1 malePalabras claves:Body Composition, bone age, Growth hormone receptor deficiency, height velocity, insulin‐like growth factor I, luteinizing hormone‐releasing hormone analogueAutores:Bachrach L.K., Davila N., Diamond F.B., Jaime Guevara-Aguirre, Martinez A., Martinez V., Moreno Z., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusBrain structure and function associated with younger adults in growth hormone receptor-deficient humans
ArticleAbstract: Growth hormone receptor deficiency (GHRD) results in short stature, enhanced insulin sensitivity, anPalabras claves:aging, COGNITION, Growth hormone receptor deficiency, IGF-1, Insulin, MRIAutores:Balasubramanian P., Braskie M.N., Enrique Terán, Guevara A., Hafzalla G.W., Jaime Guevara-Aguirre, Longo V.D., Mather M., Nashiro K., Nelson M.D., Thompson P.M., Velasco R., Wei M.Fuentes:googlescopusDespite higher body fat content, Ecuadorian subjects with Laron syndrome have less insulin resistance and lower incidence of diabetes than their relatives
ArticleAbstract: In the present pandemics of obesity and insulin resistant diabetes mellitus (DM), the specific contrPalabras claves:Growth hormone, Growth hormone receptor, Growth hormone receptor deficiency, Laron syndromeAutores:Carolina Guevara, Enrique Terán, Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Procel P., Rosado V.Fuentes:googlescopusEffects of insulin‐like growth factor I treatment on the molecular distribution of insulin‐like growth factors among different binding proteins
ArticleAbstract: The molecular distribution of insulin‐like growth factor I (IGF‐I) and IGF‐II among the IGF bindingPalabras claves:Growth hormone receptor deficiency, insulin‐like growth factor binding proteins, insulin‐like growth factor I, insulin‐like growth factor II, Lawn syndromeAutores:Baxter R.C., Diamond F.B., Fielder P.J., Gargosky S.E., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G., Vaccarello M.A., Wilson K.F.Fuentes:scopusNatural history of growth hormone receptor deficiency
Conference ObjectAbstract: This review discusses the natural history of growth hormone receptor deficiency (GHRD) in relation tPalabras claves:Body Composition, growth, Growth hormone receptor deficiency, Insulin-like growth factor I deficiency, INTELLECTUAL DEVELOPMENT, Laron syndrome, Natural HistoryAutores:Bachrach L.K., Jaime Guevara-Aguirre, Kranzier J.H., Martinez V., Rosenbloom A.L., Rosenfeld R.G.Fuentes:scopusGrowth hormone receptor deficiency in humans associates to obesity, increased body fat percentage, a healthy brain and a coordinated insulin sensitivity
ArticleAbstract: Background: We have shown that subjects with Laron syndrome (LS) due to growth hormone receptor defiPalabras claves:BRAIN, Growth hormone receptor deficiency, Insulin-like growth factor binding protein 1, Laron syndrome, obesityAutores:Antonio Wenceslao Danilo Gavilanes, Carolina Guevara, Daniela Lescano, Enrique Terán, Guevara A., Jaime Guevara-Aguirre, Longo V.D.Fuentes:googlescopusHeart rate increases in patients with growth hormone receptor deficiency treated with insulin‐like growth factor I
ArticleAbstract: Cardiac function was measured in 16 prepubertal Ecuadorean patients with growth hormone receptor defPalabras claves:Growth hormone receptor deficiency, Heart rate, insulin‐like growth factor I, Laron syndromeAutores:Diamond F.B., Hidalgo F., Jaime Guevara-Aguirre, Martinez A., Martinez V., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusPharmacokinetics of recombinant human insulin-like growth factor I given subcutaneously to healthy volunteers and to patients with growth hormone receptor deficiency
Conference ObjectAbstract: The pharmacokinetics of recombinant human insulin-like growth factor I (rhIGF-I) were studied in heaPalabras claves:Growth hormone receptor deficiency, Hypoglycaemia, Insulin-like growth factor I, Laron syndrome, pharmacokineticsAutores:Gourmelen M., Grahnen A., Heinrich U., Jaime Guevara-Aguirre, Kastrup K., Preece M., Rosenfeld R.G., Sietnieks A., Vaccarello M.A.Fuentes:scopusIs there heterozygote expression of growth hormone receptor deficiency?
ArticleAbstract: Expression of heterozygosity for the defect in the growth hormone (GH) receptor has been proposed toPalabras claves:growth hormone binding protein, Growth hormone receptor, Growth hormone receptor deficiency, heterozygote expression, insulin‐like growth factor I, Laron syndromeAutores:Fielder P.J., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G.Fuentes:scopusThe E180splice mutation in the GHR gene causing laron syndrome: Witness of a Sephardic Jewish exodus from the Iberian Peninsula to the New World?
ArticleAbstract: Laron syndrome (LS) is a genetic disorder caused by mutations in the growth hormone receptor (GHR) gPalabras claves:Growth hormone insensitivity, Growth hormone receptor, Growth hormone receptor deficiency, Laron syndrome, Lineage markers, Mitochondrial haplogroups, Y-chromosome haplogroupsAutores:Arnhold I.J.P., Cassorla F., Damiani D., Fridman C., Gonçalves F.T., Hwa V., Jaime Guevara-Aguirre, Jorge A.A.L., Laron Z., Lins T.S.S., Pinto E.M., Rosembloom A.L., Rosenfeld R.G., Shevah O.Fuentes:scopus