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Assessing insulin sensitivity and resistance in syndromes of severe short stature
ArticleAbstract: Individuals affected with two genetic syndromes identified in Ecuador have severe short stature andPalabras claves:Homeostatic minimal models, Insulin Resistance, Metabolic phenotypeAutores:Antonio Wenceslao Danilo Gavilanes, Carolina Guevara, Daniela Lescano, Enrique Terán, Guevara A., Jaime Guevara-Aguirre, Procel P., Saavedra J., Wasserfall C.H.Fuentes:scopusDespite higher body fat content, Ecuadorian subjects with Laron syndrome have less insulin resistance and lower incidence of diabetes than their relatives
ArticleAbstract: In the present pandemics of obesity and insulin resistant diabetes mellitus (DM), the specific contrPalabras claves:Growth hormone, Growth hormone receptor, Growth hormone receptor deficiency, Laron syndromeAutores:Carolina Guevara, Enrique Terán, Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Procel P., Rosado V.Fuentes:googlescopusGH and GHR signaling in human disease
ArticleAbstract: Along with its inherent properties in growth promotion, cell division and regeneration, growth hormoPalabras claves:Cáncer, DIABÉTES, Growth hormone (GH), Growth hormone receptor (GHR), Insulin-like growth factor-1 (IGF1)Autores:Enrique Terán, Guevara A., Iván Palacios, Jaime Guevara-Aguirre, Mónica Pérez, Procel P.Fuentes:googlescopusForeword from the guest editors
OtherAbstract:Palabras claves:Autores:Enrique Terán, Jaime Guevara-Aguirre, Rosenfeld R.G.Fuentes:scopusEffects of heterozygosity for the E180 splice mutation causing growth hormone receptor deficiency in Ecuador on IGF-I, IGFBP-3, and stature
ArticleAbstract: Context & objective: The Ecuadorian GH receptor deficiency (GHRD)/Laron syndrome population is the oPalabras claves:GH receptor deficiency, growth, IGF-I, IGFBP-3, Laron syndromeAutores:Baumbach L., Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Rosenbloom A.L., Saavedra J., Shuster J., Yariz K.Fuentes:scopusGrowth hormone modulates Trypanosoma cruzi infection in vitro
ArticleAbstract: Objective: Chagas disease (CD) is caused by the protozoan parasite, Trypanosoma cruzi. It affects 7Palabras claves:Chagas disease, Growth hormone, IGF-I, Laron syndrome, prolactin, TRYPANOSOMA CRUZIAutores:Basu R., Jaime Alfredo Costales, Jaime Guevara-Aguirre, Kopchick J.J., Mario J. Grijalva, Mora-Criollo P., Qian Y.Fuentes:scopusGrowth hormone receptor deficiency in humans associates to obesity, increased body fat percentage, a healthy brain and a coordinated insulin sensitivity
ArticleAbstract: Background: We have shown that subjects with Laron syndrome (LS) due to growth hormone receptor defiPalabras claves:BRAIN, Growth hormone receptor deficiency, Insulin-like growth factor binding protein 1, Laron syndrome, obesityAutores:Antonio Wenceslao Danilo Gavilanes, Carolina Guevara, Daniela Lescano, Enrique Terán, Guevara A., Jaime Guevara-Aguirre, Longo V.D.Fuentes:googlescopusInsulin resistance depends on GH counter-regulation in two syndromes of short stature
ArticleAbstract: Specific phenotypic features of subjects affected with genetic syndromes depend on peculiarities ofPalabras claves:Cyclin-dependent kinase-1c gof mutation, GH counter-regulation, Insulin Resistance, insulin secretion, Laron syndrome (LS), New syndrome (NS)Autores:Bahamonde M., Guevara A., Jaime Guevara-AguirreFuentes:scopusTreatment of growth failure in the absence of GH signaling: The Ecuadorian experience
ArticleAbstract: Recombinant human insulin-like growth factor-1 (rhIGF-1) treatment studies of growth failure in absePalabras claves:Autores:Carolina Guevara, Guevara A., Jaime Guevara-AguirreFuentes:scopus