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A novel variant in CDKN1C is associated with intrauterine growth restriction, short stature, and early-adulthood-onset diabetes
ArticleAbstract: Design, Setting, and Participants: Genomic DNA samples (15 affected and 26 unaffected from a six-genPalabras claves:Autores:Andres Zurita, Andrew S., Carolina Guevara, Dauber A., Geng J., Guo M., Hwa V., Jaime Guevara-Aguirre, Kerns S.L., Marco Guevara-Aguirre, Oddoux C., Ostrer H., Rosenfeld R.G., Shen Y.Fuentes:scopusA randomized, double blind, placebo-controlled trial on safety and efficacy of recombinant human insulin-like growth factor-I in children with growth hormone receptor deficiency
ArticleAbstract: GH insensitivity due to GH receptor deficiency is a rare autosomal recessive condition, characterizePalabras claves:Autores:Diamond F.B., Gargosky S.E., Jaime Guevara-Aguirre, Martinez L., Martinez V., Nonoshita L., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusControversy in clinical endocrinology: Reclassification of insulin-like growth factor I production and action disorders
ArticleAbstract: Context: The need for the least ambiguous terminology for disorders affecting IGF-I production and aPalabras claves:Autores:Jaime Guevara-Aguirre, Rosenbloom A.L.Fuentes:scopusGH receptor deficiency in ecuadorian adults is associated with obesity and enhanced insulin sensitivity
Conference ObjectAbstract: Context: Ecuadorian subjects with GH receptor deficiency (GHRD) have not developed diabetes, despitePalabras claves:Autores:Alfaras I., Balasubramanian P., Carolina Guevara, De Cabo R., Di Biase S., Enrique Terán, Jaime Guevara-Aguirre, Longo V.D., Marco Guevara-Aguirre, Narvaez L., Procel P., Rosenbloom A.L., Saavedra J.Fuentes:googlescopusGrowth Hormone (GH) insensitivity and insulin-like growth factor-I deficiency in inuit subjects and an ecuadorian cohort: Functional studies of two codon 180 GH receptor gene mutations (Journal of Clinical Endocrinology and Metabolism (2008) 93, (1030-1037))
OtherAbstract:Palabras claves:Autores:Fang P., Girgis R., Hwa V., Jaime Guevara-Aguirre, Little B., Pratt K.L., Rosenfeld R.G.Fuentes:scopusGrowth hormone receptor deficiency in Ecuador
OtherAbstract:Palabras claves:Autores:Francke U., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G.Fuentes:scopusGrowth hormone receptor deficiency in ecuador: Clinical and biochemical phenotype in two populations
ArticleAbstract: We have identified 56 patients with GH receptor deficiency (Laron syndrome) from two provinces in soPalabras claves:Autores:Diamond F.B., Fielder P.J., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G.Fuentes:scopusHormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome
ArticleAbstract: Profound growth failure despite elevated GH levels in GH receptor deficiency (GHRD) results from redPalabras claves:Autores:Cohen P., Diamond F.B., Fielder P.J., Gargosky S.E., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G., Vaccarello M.A., Wilson K.F.Fuentes:scopusFilter paper blood spot assay of human insulin-like growth factor I (IGF-I) and IGF-binding protein-3 and preliminary application in the evaluation of growth hormone status
ArticleAbstract: To facilitate broader applications of insulin-like growth factor I (IGF- I) and IGF-binding protein-Palabras claves:Autores:Diamandi A., Jaime Guevara-Aguirre, Khosravi M.J., Martinez V., Mistry J.Fuentes:scopusInsulin-like growth factor binding protein-3 generation as a measure of GH sensitivity
ArticleAbstract: A total of 198 subjects were randomized to either high-dose (0.05 mg/kg·d) or low-dose (0.025 mg/kg·Palabras claves:Autores:Buckway C.K., Jaime Guevara-Aguirre, Pratt K.L., Rosenfeld R.G., Selva K.A., Tjoeng E.Fuentes:scopus