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Assessing insulin sensitivity and resistance in syndromes of severe short stature
ArticleAbstract: Individuals affected with two genetic syndromes identified in Ecuador have severe short stature andPalabras claves:Homeostatic minimal models, Insulin Resistance, Metabolic phenotypeAutores:Antonio Wenceslao Danilo Gavilanes, Carolina Guevara, Daniela Lescano, Enrique Terán, Guevara A., Jaime Guevara-Aguirre, Procel P., Saavedra J., Wasserfall C.H.Fuentes:scopusDespite higher body fat content, Ecuadorian subjects with Laron syndrome have less insulin resistance and lower incidence of diabetes than their relatives
ArticleAbstract: In the present pandemics of obesity and insulin resistant diabetes mellitus (DM), the specific contrPalabras claves:Growth hormone, Growth hormone receptor, Growth hormone receptor deficiency, Laron syndromeAutores:Carolina Guevara, Enrique Terán, Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Procel P., Rosado V.Fuentes:googlescopusGrowth hormone receptor deficiency in humans associates to obesity, increased body fat percentage, a healthy brain and a coordinated insulin sensitivity
ArticleAbstract: Background: We have shown that subjects with Laron syndrome (LS) due to growth hormone receptor defiPalabras claves:BRAIN, Growth hormone receptor deficiency, Insulin-like growth factor binding protein 1, Laron syndrome, obesityAutores:Antonio Wenceslao Danilo Gavilanes, Carolina Guevara, Daniela Lescano, Enrique Terán, Guevara A., Jaime Guevara-Aguirre, Longo V.D.Fuentes:googlescopusTreatment of growth failure in the absence of GH signaling: The Ecuadorian experience
ArticleAbstract: Recombinant human insulin-like growth factor-1 (rhIGF-1) treatment studies of growth failure in absePalabras claves:Autores:Carolina Guevara, Guevara A., Jaime Guevara-AguirreFuentes:scopus