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Journal of Clinical Endocrinology and Metabolism(3)
Growth Hormone and IGF Research(2)
Diabetes Technology and Therapeutics(1)
European Journal of Endocrinology(1)
Science Translational Medicine(1)
Comparison of oral insulin spray and subcutaneous regular insulin at mealtime in type 1 diabetes
ArticleAbstract: Background: The aim of this study was to compare the glucose pharmacodynamics after oral spray insulPalabras claves:Autores:Bernstein G., Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Rosenbloom A.L., Saavedra J.Fuentes:scopusA novel variant in CDKN1C is associated with intrauterine growth restriction, short stature, and early-adulthood-onset diabetes
ArticleAbstract: Design, Setting, and Participants: Genomic DNA samples (15 affected and 26 unaffected from a six-genPalabras claves:Autores:Andres Zurita, Andrew S., Carolina Guevara, Dauber A., Geng J., Guo M., Hwa V., Jaime Guevara-Aguirre, Kerns S.L., Marco Guevara-Aguirre, Oddoux C., Ostrer H., Rosenfeld R.G., Shen Y.Fuentes:scopusDespite higher body fat content, Ecuadorian subjects with Laron syndrome have less insulin resistance and lower incidence of diabetes than their relatives
ArticleAbstract: In the present pandemics of obesity and insulin resistant diabetes mellitus (DM), the specific contrPalabras claves:Growth hormone, Growth hormone receptor, Growth hormone receptor deficiency, Laron syndromeAutores:Carolina Guevara, Enrique Terán, Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Procel P., Rosado V.Fuentes:googlescopusGH receptor deficiency in ecuadorian adults is associated with obesity and enhanced insulin sensitivity
Conference ObjectAbstract: Context: Ecuadorian subjects with GH receptor deficiency (GHRD) have not developed diabetes, despitePalabras claves:Autores:Alfaras I., Balasubramanian P., Carolina Guevara, De Cabo R., Di Biase S., Enrique Terán, Jaime Guevara-Aguirre, Longo V.D., Marco Guevara-Aguirre, Narvaez L., Procel P., Rosenbloom A.L., Saavedra J.Fuentes:googlescopusEffects of heterozygosity for the E180 splice mutation causing growth hormone receptor deficiency in Ecuador on IGF-I, IGFBP-3, and stature
ArticleAbstract: Context & objective: The Ecuadorian GH receptor deficiency (GHRD)/Laron syndrome population is the oPalabras claves:GH receptor deficiency, growth, IGF-I, IGFBP-3, Laron syndromeAutores:Baumbach L., Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Rosenbloom A.L., Saavedra J., Shuster J., Yariz K.Fuentes:scopusGrowth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
ArticleAbstract: Mutations in growth signaling pathways extend life span, as well as protect against age-dependent DNPalabras claves:Autores:Balasubramanian P., Cheng C.W., Cohen P., De Cabo R., Hwang D., Ingles S., Jaime Guevara-Aguirre, Longo V.D., Madia F., Marco Guevara-Aguirre, Martin-Montalvo A., Saavedra J., Wei M.Fuentes:scopusIntrauterine and postnatal growth failure with normal GH/IGF1 axis and insulin-resistant diabetes in a consanguineous kinship
ArticleAbstract: Objective: To describe the clinical and biochemical features, and perform molecular analysis for canPalabras claves:Autores:Fang P., Hwa V., Jaime Guevara-Aguirre, Kerns S.L., Marco Guevara-Aguirre, Ostrer H., Procel P., Rosenbloom A.L., Rosenfeld R.G., Saavedra J.Fuentes:scopusRecommended IGF-I dosage causes greater fat accumulation and osseous maturation than lower dosage and may compromise long-term growth effects
ArticleAbstract: Context: The maximum dose of IGF-I recommended for treatment of GH insensitivity is commonly used. OPalabras claves:Autores:Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Procel P., Rosenbloom A.L., Saavedra J.Fuentes:scopus