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Journal of Clinical Endocrinology and Metabolism(14)
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scopus(118)
Circadian rhythms of 11-oxygenated C19 steroids and Δ5-steroid sulfates in healthy men
ArticleAbstract: Background: Many hormones display distinct circadian rhythms, driven by ce ntral regulators, hormonaPalabras claves:Autores:Chen X., Rainey W.E., Rege J., Richard J. Auchus, Turcu A.F., Veldhuis J.D., Yang R., Zhao L.Fuentes:scopusCirculating 11-oxygenated androgens across species
ArticleAbstract: The androgen precursors, dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are produced in highPalabras claves:11-oxyandrogens, Adrenal, Primates, steroidsAutores:Conley A.J., Elsey R.M., Garber S., Rainey W.E., Rege J., Richard J. Auchus, Turcu A.F.Fuentes:scopusClinical, biochemical, and molecular characterization of macronodular adrenocortical hyperplasia of the zona reticularis: A new syndrome
ArticleAbstract: Context: Macronodular adrenocortical hyperplasia classically presents with progressive hypercortisolPalabras claves:Autores:Carrick K., Ghayee H.K., Miller W.L., Nwariaku F.E., Rainey W.E., Rege J., Richard J. Auchus, Watumull L.Fuentes:scopusCofactors, redox state, and directional preferences of hydroxysteroid dehydrogenases
ReviewAbstract: The hydroxysteroid dehydrogenases (HSDs) interconvert pairs of weak and potent steroids, thus servinPalabras claves:androgen, Equilibrium, Estrogen, Glucocorticoid, Hydroxysteroid dehydrogenase, Nicotinamide cofactor, Redox stateAutores:Agarwal A.K., Andersson S., Brandmaier A., Chattopadhyay A., Khan N., Papari-Zareei M., Rambally S., Richard J. Auchus, Sharma K.K., Sherbet D.P.Fuentes:scopusComparison of the hamster and human adrenal P450c17 (17α-hydroxylase/17,20-lyase) using site-directed mutagenesis and molecular modeling
ArticleAbstract: In order to understand the activity specificity of the hamster cytochrome P450 17α-hydroxylase/17,20Palabras claves:17,20-Lyase, 17α-hydroxylase, 3D modeling, Adrenals, CYP17, Cytochrome P450c17, HÁMSTER, Human, Mutants, Site-directed mutagenesisAutores:LeHoux J.G., Mathieu A.P., Richard J. AuchusFuentes:scopusComprehensive 2-dimensional gas chromatography fast quadrupole mass spectrometry (GC×GC-qMS) for urinary steroid profiling: Mass spectral characteristics with chemical ionization
ArticleAbstract: Comprehensive 2-dimensional gas chromatography (GC×GC), coupled to either a time of flight mass specPalabras claves:Anabolic androgenic steroids, Comprehensive 2-dimensional gas chromatography, Electron impact ionization, Positive chemical ionization, Quadrupole mass spectrometryAutores:Brenna J.T., Richard J. Auchus, Tobias H.J., Zhang Y.Fuentes:scopusComprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma
ArticleAbstract: We report a comprehensive molecular characterization of pheochromocytomas and paragangliomas (PCCs/PPalabras claves:CSDE1, expression subtypes, Genomics, MAML3, Metástasis, molecular profiling, Paraganglioma, pheochromocytoma, Sequencing, TCGAAutores:Akbani R., Ally A., Amar L., Amelio A.L., Arachchi H., Asa S.L., Auman J.T., Baertsch R., Balasundaram M., Balu S., Bartsch D.K., Baudin E., Bauer T., Beaver A., Benz C., Beroukhim R., Beuschlein F., Bodenheimer T., Boice L., Bowen J., Bowlby R., Brooks D., Carlsen R., Carter S., Cassol C.A., Cherniack A.D., Chin L., Cho J., Chuah E., Chudamani S., Cope L., Crain D., Curley E., Danilova L., De Cubas A.A., de Krijger R.R., Demchok J.A., Deutschbein T., Dhalla N., Dimmock D., Dinjens W.N.M., Else T., Eng C., Eschbacher J., Fassnacht M., Felau I., Feldman M., Ferguson M.L., Fiddes I., Fishbein L., Frazer S., Gabriel S.B., Gardner J., Gastier-Foster J.M., Gehlenborg N., Gerken M., Getz G., Geurts J., Ghayee H.K., Gimenez-Roqueplo A.P., Giordano T.J., Goldman M., Graim K., Gupta M., Haan D., Hahner S., Hantel C., Haussler D., Hayes D.N., Heiman D.I., Hoadley K.A., Holt R.A., Hoyle A.P., Huang M., Hunt B., Hutter C.M., Jefferys S.R., Johnson A.R., Jones C.D., Jones S.J.M., Kasaian K., Kebebew E., Kim J., Kimes P., Knijnenburg T., Korpershoek E., Lander E., Lawrence M.S., Lechan R., Leshchiner I., Lichtenberg T.M., Ling S., Makowski L., Murray B.A., Rathmell W.K., Richard J. Auchus, Robertson A.G., Tischler A.S., Walter V., Wenz B.Fuentes:scopusBasic concepts and recent developments in human steroid hormone biosynthesis
ReviewAbstract: The biosynthesis of steroid hormones requires the coordinated expression of the enzymes that comprisPalabras claves:Adrenal gland, Adrenal tumors, Androgen biosynthesis, Congenital adrenal hyperplasia, Steroid metabolism, steroidogenesisAutores:Ghayee H.K., Richard J. AuchusFuentes:scopusBiochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17β-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells
ArticleAbstract: Human 17β-hydroxysteroid dehydrogenase types 1 and 2 (17βHSD1 and 17βHSD2) regulate estrogen potencyPalabras claves:Autores:Akbar S., Guryev O.L., Mizrachi D., Papari-Zareei M., Rambally S., Richard J. Auchus, Sherbet D.P.Fuentes:scopusBone Morphogenetic Protein-4 (BMP4): A paracrine regulator of human adrenal C<inf>19</inf> steroid synthesis
ArticleAbstract: Bone morphogenetic proteins (BMPs) comprise one of the largest subgroups in the TGF-β ligand superfaPalabras claves:Autores:Nishimoto H.K., Nishimoto K., Rainey W.E., Rege J., Richard J. Auchus, Rodgers R.J.Fuentes:scopus