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Journal of Clinical Endocrinology and Metabolism(6)
Journal of Steroid Biochemistry and Molecular Biology(3)
European Journal of Endocrinology(2)
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Adrenocortical Carcinoma: Basic Science and Clinical Concepts(1)
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Farmacología y terapéutica(16)
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scopus(20)
Clinical advances in the pharmacotherapy of congenital adrenal hyperplasia
ReviewAbstract: Background: Patients with 21-hydroxylase deficiency congenital adrenal hyperplasia (21OHD-CAH) havePalabras claves:Autores:Prete A., Richard J. Auchus, Ross R.J.Fuentes:scopusClinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer
ArticleAbstract: Context: Abiraterone acetate is a small-molecule cytochrome P450 17A1 (CYP17A1) inhibitor that is acPalabras claves:Autores:Arlt W., Attard G., Cassidy A.M., De Bono J.S., Dowsett M., Folkerd E., Hughes B.A., Oommen N.B., Reid A.H.M., Richard J. Auchus, Thompson E.Fuentes:scopus3β-hydroxysteroid dehydrogenase is a possible pharmacological target in the treatment of castration-resistant prostate cancer
ArticleAbstract: Prostate cancer usually responds to androgen deprivation therapy, although the response in metastatiPalabras claves:Autores:Evaul K., Li R., Papari-Zareei M., Richard J. Auchus, Sharifi N.Fuentes:scopusA-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone
ArticleAbstract: Abiraterone acetate is a potent inhibitor of human cytochrome P450c17 (CYP17A1, 17α-hydroxylase/17,2Palabras claves:abiraterone, androgen, CYP17A1, Cytochrome p450, Enzymology, Prostate cancer, steroidogenesisAutores:Bratoeff E., Garrido M., Peng H.M., Richard J. Auchus, Upadhyay S.K., Yoshimoto F.K.Fuentes:scopusDevelopment and validation of a novel LC–MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation of diastereoisomers without use of a chiral column
ArticleAbstract: Abiraterone acetate (AA), the prodrug of abiraterone, is FDA-approved for the treatment of castratioPalabras claves:abiraterone, LC–MS/MS, Metabolites, Method validation, Prostate cancerAutores:Alyamani M., Anderson D., Li Z., Richard J. Auchus, Sharifi N., Upadhyay S.K.Fuentes:scopusCrinecerfont Lowers Elevated Hormone Markers in Adults with 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia
ArticleAbstract: Context: Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21OHD) is charactePalabras claves:17-hydroxyprogesterone, 21-hydroxylase deficiency, Congenital adrenal hyperplasia, crinecerfont, NBI-74788Autores:Chan J.L., Davis S.M., Farber R.H., Fechner P.Y., Giri N., Imel E.A., Richard J. Auchus, Roberts E., Sarafoglou K., Sturgeon J., Vogiatzi M.G.Fuentes:scopusAbiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency
ArticleAbstract: Context: Chronic supraphysiological glucocorticoid therapy controls the androgen excess of 21-hydroxPalabras claves:Autores:Buschur E.O., Chang A.Y., Gonzalez M., Hammer G.D., Jiao J., Madrigal D., Ramm C.A., Richard J. Auchus, Smit J.W., Wang G., Xu X.S., Yu M.K.Fuentes:scopusAbiraterone acetate treatment lowers 11-oxygenated androgens
ArticleAbstract: Context: The human adrenal is the dominant source of androgens in castration-resistant prostate cancPalabras claves:Autores:Alyamani M., O'Day P.J., Richard J. Auchus, Sharifi N., Wright C.Fuentes:scopusAbiraterone inhibits 3β-hydroxysteroid dehydrogenase: A rationale for increasing drug exposure in castration-resistant prostate cancer
ArticleAbstract: Purpose: Treatment with abiraterone (abi) acetate prolongs survival in castration-resistant prostatePalabras claves:Autores:Chang K.H., Evaul K., Li R., Liu J., Richard J. Auchus, Sharifi N., Sharma K.K., Yoshimoto J.A.Fuentes:scopusEditorial: The new instructions to authors for the reporting of steroid hormone measurements
OtherAbstract:Palabras claves:Autores:Haisenleder D.J., Hall J.E., Handelsman D., Hankinson S., Richard J. Auchus, Rosner W., Singh R.J., Sluss P.M., Stanczyk F.Z., Wierman M.E.Fuentes:scopus