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Journal of Clinical Endocrinology and Metabolism(41)
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"Getting from here to there"-mechanisms and limitations to the activation of the androgen receptor in castration-resistant prostate cancer
ReviewAbstract: Despite the clinical regression that typifies the initial response of advanced prostate cancer to goPalabras claves:androgen receptor, Androgens, Steroid metabolismAutores:McPhaul M., Richard J. Auchus, Sharifi N.Fuentes:scopus"Subclinical Cushing's syndrome" is not subclinical: improvement after adrenalectomy in 9 patients
ArticleAbstract: Background: A subgroup of patients with adrenal cortisol hypersecretion fails to meet the biochemicaPalabras claves:Autores:Chang A.Y., Holt S.A., Juneja K., Mitchell I., Nwariaku F.E., Richard J. Auchus, Snyder W.Fuentes:scopus11-Oxygenated Androgens Useful in the Setting of Discrepant Conventional Biomarkers in 21-Hydroxylase Deficiency
ArticleAbstract: Context: Serum 17-hydroxyprogesterone (17OHP) and androstenedione (A4) are the conventional biomarkePalabras claves:alternate androgens, androgen excess, Biomarkers, Congenital adrenal hyperplasia, monitoring therapy, steroidogenesisAutores:Brookner B., Jha S., Merke D.P., Richard J. Auchus, Sinaii N., Turcu A.F.Fuentes:scopus11-Oxygenated androgens are biomarkers of adrenal volume and testicular adrenal rest tumors in 21-hydroxylase deficiency
ArticleAbstract: Context: Patients with 21-hydroxylase deficiency (21OHD) have long-term complications, resulting froPalabras claves:Autores:Avila N.A., Elman M.S., Mallappa A., Marko J., Merke D.P., Rao H., Richard J. Auchus, Tsodikov A., Turcu A.F.Fuentes:scopus11-Oxygenated androgens in health and disease
ReviewAbstract: The adrenal gland is a source of sex steroid precursors, and its activity is particularly relevant dPalabras claves:Autores:Rainey W.E., Rege J., Richard J. Auchus, Turcu A.F.Fuentes:scopus24-Hour Profiles of 11-Oxygenated C<inf>19</inf> Steroids and Δ<sup>5</sup>-Steroid Sulfates during Oral and Continuous Subcutaneous Glucocorticoids in 21-Hydroxylase Deficiency
ArticleAbstract: Background: Optimal management of androgen excess in 21-hydroxylase deficiency (21OHD) remains challPalabras claves:11-oxyandrogens, 21-hydroxylase deficiency, CAH, Circadian hormones, Congenital adrenal hyperplasia, cortisol 24-hour profileAutores:Byrd J.B., Chen X., Mallappa A., Merke D.P., Nanba A.T., Nella A.A., Richard J. Auchus, Turcu A.F., Zhao L.Fuentes:scopus3β-hydroxysteroid dehydrogenase is a possible pharmacological target in the treatment of castration-resistant prostate cancer
ArticleAbstract: Prostate cancer usually responds to androgen deprivation therapy, although the response in metastatiPalabras claves:Autores:Evaul K., Li R., Papari-Zareei M., Richard J. Auchus, Sharifi N.Fuentes:scopusA Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia
ArticleAbstract: Context: Patients with classic congenital adrenal hyperplasia (CAH) often require supraphysiologic gPalabras claves:adrenal hypertrophy, ATR-101, Clinical trial, Congenital adrenal hyperplasia, nevanimibeAutores:Chang A.Y., El-Maouche D., Joyal E.G., Lin V.H., Merke D.P., Mohideen P., Plaunt M.R., Richard J. Auchus, Turcu A.F., Vogiatzi M.G., Weintraub L.Fuentes:scopusA Real Saline Challenge: Diagnosing Primary Aldosteronism in the Setting of Chronic Kidney Disease
ArticleAbstract: Primary aldosteronism (PA) is the most common cause of secondary hypertension but remains largely unPalabras claves:Chronic kidney disease, Hypertension, primary aldosteronismAutores:Ganji N., Hamidi O., Mirfakhraee S., Richard J. Auchus, Rodriguez M.Fuentes:scopusA high rate of novel CYP11B1 mutations in Saudi Arabia
ArticleAbstract: Despite ethnic variation, 11 β-hydroxylase deficiency (11β-OHD) has generally been considered the sePalabras claves:Ambiguous genitalia, Congenital adrenal hyperplasia, CYP11B1, MutationsAutores:Al-Sagheir A., Alhomaidah D., Alswailem M., Alzahrani A., Alzahrani O., Bin-Abbas B., Capper C.P., Murugan A., Qasem E., Richard J. AuchusFuentes:scopus