Mostrando 10 resultados de: 120
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Journal of Clinical Endocrinology and Metabolism(23)
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scopus(120)
10 The oestrogen receptor
ArticleAbstract: During the past 30 years, we have learned a great deal about the molecular details whereby the ovariPalabras claves:Autores:Fuqua S.A.W., Richard J. AuchusFuentes:scopus24-Hour Profiles of 11-Oxygenated C<inf>19</inf> Steroids and Δ<sup>5</sup>-Steroid Sulfates during Oral and Continuous Subcutaneous Glucocorticoids in 21-Hydroxylase Deficiency
ArticleAbstract: Background: Optimal management of androgen excess in 21-hydroxylase deficiency (21OHD) remains challPalabras claves:11-oxyandrogens, 21-hydroxylase deficiency, CAH, Circadian hormones, Congenital adrenal hyperplasia, cortisol 24-hour profileAutores:Byrd J.B., Chen X., Mallappa A., Merke D.P., Nanba A.T., Nella A.A., Richard J. Auchus, Turcu A.F., Zhao L.Fuentes:scopus3β-hydroxysteroid dehydrogenase is a possible pharmacological target in the treatment of castration-resistant prostate cancer
ArticleAbstract: Prostate cancer usually responds to androgen deprivation therapy, although the response in metastatiPalabras claves:Autores:Evaul K., Li R., Papari-Zareei M., Richard J. Auchus, Sharifi N.Fuentes:scopusA Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia
ArticleAbstract: Context: Patients with classic congenital adrenal hyperplasia (CAH) often require supraphysiologic gPalabras claves:adrenal hypertrophy, ATR-101, Clinical trial, Congenital adrenal hyperplasia, nevanimibeAutores:Chang A.Y., El-Maouche D., Joyal E.G., Lin V.H., Merke D.P., Mohideen P., Plaunt M.R., Richard J. Auchus, Turcu A.F., Vogiatzi M.G., Weintraub L.Fuentes:scopusA reninssance in primary aldosteronism testing: Obstacles and opportunities for screening, diagnosis, and management
OtherAbstract:Palabras claves:Autores:Cavalier E., Diamandis E.P., Holmes D., Raizman J.E., Richard J. Auchus, Stowasser M.Fuentes:scopusA-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone
ArticleAbstract: Abiraterone acetate is a potent inhibitor of human cytochrome P450c17 (CYP17A1, 17α-hydroxylase/17,2Palabras claves:abiraterone, androgen, CYP17A1, Cytochrome p450, Enzymology, Prostate cancer, steroidogenesisAutores:Bratoeff E., Garrido M., Peng H.M., Richard J. Auchus, Upadhyay S.K., Yoshimoto F.K.Fuentes:scopusAN INDIVIDUALIZED APPROACH TO THE EVALUATION AND MANAGEMENT OF PRIMARY ALDOSTERONISM
ReviewAbstract: OBJECTIVE: With the increased emphasis on personalized and individualized medicine, the American AssPalabras claves:Autores:Malchoff C.D., Richard J. Auchus, Vaidya A.Fuentes:scopusClinical advances in the pharmacotherapy of congenital adrenal hyperplasia
ReviewAbstract: Background: Patients with 21-hydroxylase deficiency congenital adrenal hyperplasia (21OHD-CAH) havePalabras claves:Autores:Prete A., Richard J. Auchus, Ross R.J.Fuentes:scopusClinical and Hormonal Response to Mifepristone Therapy in 2 Patients with ACTH-Independent Cushing Syndrome
ArticleAbstract: Objective: Cushing syndrome is an endocrine disorder resulting from prolonged exposure to excess corPalabras claves:Autores:Moraitis A.G., Richard J. AuchusFuentes:scopusClinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer
ArticleAbstract: Context: Abiraterone acetate is a small-molecule cytochrome P450 17A1 (CYP17A1) inhibitor that is acPalabras claves:Autores:Arlt W., Attard G., Cassidy A.M., De Bono J.S., Dowsett M., Folkerd E., Hughes B.A., Oommen N.B., Reid A.H.M., Richard J. Auchus, Thompson E.Fuentes:scopus