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Current Opinion in Endocrinology, Diabetes and Obesity(4)
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scopus(25)
Clinical significance of 11-oxygenated androgens
ReviewAbstract: Purpose of review The adrenal gland is considered a source of weak androgens, such as dehydroepiandrPalabras claves:11-ketotestosterone, 11-oxygenated 19-carbon steroids, 11β-hydroxyandrostenedione, Adrenal, Androgens, castration resistant prostate cancer, Congenital adrenal hyperplasia, polycystic ovarian syndromeAutores:Richard J. Auchus, Turcu A.F.Fuentes:scopusBasic concepts and recent developments in human steroid hormone biosynthesis
ReviewAbstract: The biosynthesis of steroid hormones requires the coordinated expression of the enzymes that comprisPalabras claves:Adrenal gland, Adrenal tumors, Androgen biosynthesis, Congenital adrenal hyperplasia, Steroid metabolism, steroidogenesisAutores:Ghayee H.K., Richard J. AuchusFuentes:scopus11-Oxygenated Androgens Useful in the Setting of Discrepant Conventional Biomarkers in 21-Hydroxylase Deficiency
ArticleAbstract: Context: Serum 17-hydroxyprogesterone (17OHP) and androstenedione (A4) are the conventional biomarkePalabras claves:alternate androgens, androgen excess, Biomarkers, Congenital adrenal hyperplasia, monitoring therapy, steroidogenesisAutores:Brookner B., Jha S., Merke D.P., Richard J. Auchus, Sinaii N., Turcu A.F.Fuentes:scopus24-Hour Profiles of 11-Oxygenated C<inf>19</inf> Steroids and Δ<sup>5</sup>-Steroid Sulfates during Oral and Continuous Subcutaneous Glucocorticoids in 21-Hydroxylase Deficiency
ArticleAbstract: Background: Optimal management of androgen excess in 21-hydroxylase deficiency (21OHD) remains challPalabras claves:11-oxyandrogens, 21-hydroxylase deficiency, CAH, Circadian hormones, Congenital adrenal hyperplasia, cortisol 24-hour profileAutores:Byrd J.B., Chen X., Mallappa A., Merke D.P., Nanba A.T., Nella A.A., Richard J. Auchus, Turcu A.F., Zhao L.Fuentes:scopus46,XX DSD: The masculinised female
ReviewAbstract: The 46,XX disorders of sex development (DSDs) cause virilisation or masculinisation of the female foPalabras claves:46,XX DSD, Adrenal gland, androgen, Congenital adrenal hyperplasia, steroidogenesis, VirilisationAutores:Chang A.Y., Richard J. AuchusFuentes:scopusA Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia
ArticleAbstract: Context: Patients with classic congenital adrenal hyperplasia (CAH) often require supraphysiologic gPalabras claves:adrenal hypertrophy, ATR-101, Clinical trial, Congenital adrenal hyperplasia, nevanimibeAutores:Chang A.Y., El-Maouche D., Joyal E.G., Lin V.H., Merke D.P., Mohideen P., Plaunt M.R., Richard J. Auchus, Turcu A.F., Vogiatzi M.G., Weintraub L.Fuentes:scopusA high rate of novel CYP11B1 mutations in Saudi Arabia
ArticleAbstract: Despite ethnic variation, 11 β-hydroxylase deficiency (11β-OHD) has generally been considered the sePalabras claves:Ambiguous genitalia, Congenital adrenal hyperplasia, CYP11B1, MutationsAutores:Al-Sagheir A., Alhomaidah D., Alswailem M., Alzahrani A., Alzahrani O., Bin-Abbas B., Capper C.P., Murugan A., Qasem E., Richard J. AuchusFuentes:scopusCongenital adrenal hyperplasia in adults
ReviewAbstract: Purpose of Review: Patients born with congenital adrenal hyperplasia (CAH), the majority of which isPalabras claves:21-hydroxylase deficiency, 46XX DSD, Adrenal gland, androgen, Congenital adrenal hyperplasia, steroidogenesis, Testicular adrenal rest tissue, VirilizationAutores:Richard J. AuchusFuentes:scopusCrinecerfont Lowers Elevated Hormone Markers in Adults with 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia
ArticleAbstract: Context: Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21OHD) is charactePalabras claves:17-hydroxyprogesterone, 21-hydroxylase deficiency, Congenital adrenal hyperplasia, crinecerfont, NBI-74788Autores:Chan J.L., Davis S.M., Farber R.H., Fechner P.Y., Giri N., Imel E.A., Richard J. Auchus, Roberts E., Sarafoglou K., Sturgeon J., Vogiatzi M.G.Fuentes:scopusDefects in androgen biosynthesis causing 46,XY disorders of sexual development
ArticleAbstract: At least one genetic defect in each reaction of the classical androgen biosynthesis pathway has beenPalabras claves:46 XY DSD, androgen, Congenital adrenal hyperplasia, Enzyme, Steroid, steroidogenesis, Testis, TestosteroneAutores:Miller W.L., Richard J. AuchusFuentes:scopus