Mostrando 10 resultados de: 24
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Journal of Steroid Biochemistry and Molecular Biology(4)
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Reviews in Endocrine and Metabolic Disorders(2)
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Current Opinion in Endocrinology, Diabetes and Obesity(1)
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scopus(24)
Basic concepts and recent developments in human steroid hormone biosynthesis
ReviewAbstract: The biosynthesis of steroid hormones requires the coordinated expression of the enzymes that comprisPalabras claves:Adrenal gland, Adrenal tumors, Androgen biosynthesis, Congenital adrenal hyperplasia, Steroid metabolism, steroidogenesisAutores:Ghayee H.K., Richard J. AuchusFuentes:scopusAndrogen biosynthesis and gene defects
Book PartAbstract: Formation of the male external genitalia in human beings requires the production of dihydrotestosterPalabras claves:androgen, Cytochrome p450, Dehydrogenase, Dihydrotestosterone, Disorder of sex development, External genitalia, Hydroxysteroid, Hypogonadism, steroidogenesis, Testis, Testosterone, VirilizationAutores:Richard J. Auchus, Turcu A.F.Fuentes:scopus11-Oxygenated Androgens Useful in the Setting of Discrepant Conventional Biomarkers in 21-Hydroxylase Deficiency
ArticleAbstract: Context: Serum 17-hydroxyprogesterone (17OHP) and androstenedione (A4) are the conventional biomarkePalabras claves:alternate androgens, androgen excess, Biomarkers, Congenital adrenal hyperplasia, monitoring therapy, steroidogenesisAutores:Brookner B., Jha S., Merke D.P., Richard J. Auchus, Sinaii N., Turcu A.F.Fuentes:scopus46,XX DSD: The masculinised female
ReviewAbstract: The 46,XX disorders of sex development (DSDs) cause virilisation or masculinisation of the female foPalabras claves:46,XX DSD, Adrenal gland, androgen, Congenital adrenal hyperplasia, steroidogenesis, VirilisationAutores:Chang A.Y., Richard J. AuchusFuentes:scopusA-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone
ArticleAbstract: Abiraterone acetate is a potent inhibitor of human cytochrome P450c17 (CYP17A1, 17α-hydroxylase/17,2Palabras claves:abiraterone, androgen, CYP17A1, Cytochrome p450, Enzymology, Prostate cancer, steroidogenesisAutores:Bratoeff E., Garrido M., Peng H.M., Richard J. Auchus, Upadhyay S.K., Yoshimoto F.K.Fuentes:scopusCongenital adrenal hyperplasia in adults
ReviewAbstract: Purpose of Review: Patients born with congenital adrenal hyperplasia (CAH), the majority of which isPalabras claves:21-hydroxylase deficiency, 46XX DSD, Adrenal gland, androgen, Congenital adrenal hyperplasia, steroidogenesis, Testicular adrenal rest tissue, VirilizationAutores:Richard J. AuchusFuentes:scopusDefects in androgen biosynthesis causing 46,XY disorders of sexual development
ArticleAbstract: At least one genetic defect in each reaction of the classical androgen biosynthesis pathway has beenPalabras claves:46 XY DSD, androgen, Congenital adrenal hyperplasia, Enzyme, Steroid, steroidogenesis, Testis, TestosteroneAutores:Miller W.L., Richard J. AuchusFuentes:scopusAdrenal Gland
Book PartAbstract: The adrenal cortex is actually four separate glands, each with a principal product. The adrenal cortPalabras claves:adrenal cortex, Adrenal gland, Adrenal medulla, aldosterone, cortisol, Dehydroepiandrosterone, steroidogenesis, ZonationAutores:Richard J. AuchusFuentes:scopusAdrenal Steroidogenesis and Congenital Adrenal Hyperplasia
ReviewAbstract: Adrenal steroidogenesis is a dynamic process, reliant on de novo synthesis from cholesterol, under tPalabras claves:21-hydroxylase, Adrenal insufficiency, Ambiguous genitalia, androgen, Congenital adrenal hyperplasia, Disorder of sex development, Steroid hydroxylase, steroidogenesisAutores:Richard J. Auchus, Turcu A.F.Fuentes:scopusFunctional characterization of the G162R and D216H genetic variants of human CYP17A1
ArticleAbstract: Cytochrome P450 17A1 (CYP17A1) is a dual-function enzyme catalyzing reactions necessary for cortisolPalabras claves:CYP17A1, Cytochrome p450, Proteasome, steroidogenesis, UbiquitinationAutores:Capper C.P., Hollenberg P.F., Johnson M.D., Larios J.M., Liu J., McIntosh L.R., Osawa Y., Rae J.M., Richard J. AuchusFuentes:scopus