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scopus(72)
"Getting from here to there"-mechanisms and limitations to the activation of the androgen receptor in castration-resistant prostate cancer
ReviewAbstract: Despite the clinical regression that typifies the initial response of advanced prostate cancer to goPalabras claves:androgen receptor, Androgens, Steroid metabolismAutores:McPhaul M., Richard J. Auchus, Sharifi N.Fuentes:scopusA Stereoselective Synthesis of Cyclopentene Derivatives from 1,3-Dienes
ArticleAbstract:Palabras claves:Autores:Danheiser R.L., Kadonaga J.T., Martinez-Davila C., Richard J. AuchusFuentes:scopusA randomized, placebo-controlled proof-of-concept, crossover trial of phenytoin for hydrocortisone-induced declarative memory changes
ArticleAbstract: Background: Corticosteroid excess is associated with declarative memory impairment and hippocampal aPalabras claves:Anticonvulsant, COGNITION, Corticosteroid, FMRI, hippocampusAutores:Brown E., Carmody T., Denniston D., Diaz-Arrastia R., Lu H., Richard J. Auchus, Tamminga C., Thomas B., Uh J.Fuentes:scopusA rare example of extremely strong carbon—carbon coupling: Analysis of <sup>13</sup>C and <sup>1</sup>H NMR spectra of a <sup>13</sup>C<inf>2</inf>‐acetylenic ketone
ArticleAbstract: NMR spectra are reported for an acetylenic ketone enriched with 13C in the acetylenic carbon atoms tPalabras claves:AB/ABX spin system, INADEQUATE acetylenic ketones, strong carbon‐carbon couplingAutores:Covey D.F., d'Avignon A., Richard J. AuchusFuentes:scopusA-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone
ArticleAbstract: Abiraterone acetate is a potent inhibitor of human cytochrome P450c17 (CYP17A1, 17α-hydroxylase/17,2Palabras claves:abiraterone, androgen, CYP17A1, Cytochrome p450, Enzymology, Prostate cancer, steroidogenesisAutores:Bratoeff E., Garrido M., Peng H.M., Richard J. Auchus, Upadhyay S.K., Yoshimoto F.K.Fuentes:scopusCofactors, redox state, and directional preferences of hydroxysteroid dehydrogenases
ReviewAbstract: The hydroxysteroid dehydrogenases (HSDs) interconvert pairs of weak and potent steroids, thus servinPalabras claves:androgen, Equilibrium, Estrogen, Glucocorticoid, Hydroxysteroid dehydrogenase, Nicotinamide cofactor, Redox stateAutores:Agarwal A.K., Andersson S., Brandmaier A., Chattopadhyay A., Khan N., Papari-Zareei M., Rambally S., Richard J. Auchus, Sharma K.K., Sherbet D.P.Fuentes:scopusComparison of the hamster and human adrenal P450c17 (17α-hydroxylase/17,20-lyase) using site-directed mutagenesis and molecular modeling
ArticleAbstract: In order to understand the activity specificity of the hamster cytochrome P450 17α-hydroxylase/17,20Palabras claves:17,20-Lyase, 17α-hydroxylase, 3D modeling, Adrenals, CYP17, Cytochrome P450c17, HÁMSTER, Human, Mutants, Site-directed mutagenesisAutores:LeHoux J.G., Mathieu A.P., Richard J. AuchusFuentes:scopusBradykinin-induced changes in myo-inositol 1,2-(cyclic)phosphate in rabbit papillary collecting tubule cells
ArticleAbstract: Rabbit renal pipillary collecting tubule cells were harvested and grown in primary cultures. When laPalabras claves:(Rabbit), Bradykinin, Inositol 1,2-(cyclic)phosphateAutores:Morrison A.R., Richard J. Auchus, Shayman J.A.Fuentes:scopusBrief report: Measurement of 18-hydroxycorticosterone during adrenal vein sampling for primary aldosteronism
ArticleAbstract: Context: In primary aldosteronism, elevated serum 18-hydroxycorticosterone (18OHB) suggests aldosterPalabras claves:Autores:Chandler D.W., Chokshi N., Dolmatch B.L., Holt S.A., Josephs S.C., Leonard D., Lopera J., Nesbitt S.D., Nwariaku F.E., Richard J. Auchus, Singeetham S., Trimmer C.K., Victor R.G., Vongpatanasin W., Wians F.H.Fuentes:scopusAn innovative approach to noninvasive dynamic adrenal testing
OtherAbstract:Palabras claves:Adrenal, Cosyntropin, Dynamic testing, Saliva cortisolAutores:Richard J. AuchusFuentes:scopus