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Classics in cardiovascular endocrinology: Aldosterone action beyond electrolytes
OtherAbstract:Palabras claves:Autores:Richard J. AuchusFuentes:scopusBiochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17β-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells
ArticleAbstract: Human 17β-hydroxysteroid dehydrogenase types 1 and 2 (17βHSD1 and 17βHSD2) regulate estrogen potencyPalabras claves:Autores:Akbar S., Guryev O.L., Mizrachi D., Papari-Zareei M., Rambally S., Richard J. Auchus, Sherbet D.P.Fuentes:scopusBone Morphogenetic Protein-4 (BMP4): A paracrine regulator of human adrenal C<inf>19</inf> steroid synthesis
ArticleAbstract: Bone morphogenetic proteins (BMPs) comprise one of the largest subgroups in the TGF-β ligand superfaPalabras claves:Autores:Nishimoto H.K., Nishimoto K., Rainey W.E., Rege J., Richard J. Auchus, Rodgers R.J.Fuentes:scopus3β-hydroxysteroid dehydrogenase is a possible pharmacological target in the treatment of castration-resistant prostate cancer
ArticleAbstract: Prostate cancer usually responds to androgen deprivation therapy, although the response in metastatiPalabras claves:Autores:Evaul K., Li R., Papari-Zareei M., Richard J. Auchus, Sharifi N.Fuentes:scopus5α-androstane-3α,17β-diol is formed in tammar wallaby pouch young testes by a pathway involving 5α-pregnane-3α,17α-diol-20-one as a key intermediate
ArticleAbstract: The synthetic pathway by which 5α-androstane-3α,17β-diol (5α-adiol) is formed in the testes of tammaPalabras claves:Autores:Estabrook R.W., Guryev O.L., Leihy M.W., Osborn S.M., Renfree M.B., Richard J. Auchus, Shaw G., Wilson J.D.Fuentes:scopusDeletion of Androgen Receptor in LepRb Cells Improves Estrous Cycles in Prenatally Androgenized Mice
ArticleAbstract: Androgens are steroid hormones crucial for sexual differentiation of the brain and reproductive funcPalabras claves:androgen receptor, Estrous cycle, hyperandrogenism, hypothalamus, leptin receptorAutores:Allen S.J., Beekly B.G., Burger L.L., Cara A.L., Elias C.F., Henson E.L., Moenter S.M., Myers M.G., Richard J. AuchusFuentes:scopusArginine 276 controls the directional preference of AKR1C9 (rat liver 3α-hydroxysteroid dehydrogenase) in human embryonic kidney 293 cells
ArticleAbstract: Rat liver AKR1C9 is the best-studied 3α-hydroxysteroid dehydrogenase (3αHSD) of the aldo-keto reductPalabras claves:Autores:Brandmaier A., Papari-Zareei M., Richard J. AuchusFuentes:scopusMolecular evolution of adrenarche: Structural and functional analysis of P450c17 from four rimate species
ArticleAbstract: Adrenarche is the prepubertal onset of increased adrenal secretion of 19-carbon steroids, especiallyPalabras claves:Autores:Arlt W., Martens J.W.M., Miller W.L., Richard J. Auchus, Song M., Wang J.Fuentes:scopusObesity-induced infertility in male mice is associated with disruption of Crisp4 expression and sperm fertilization capacity
ArticleAbstract: Approximately 15% of human couples of reproductive age have impaired fertility, and the male componePalabras claves:Autores:Borges B.C., Cruz-Machado S.D.S., Elias C.F., Garcia-Galiano D., Gavrilina G.B., Hammoud S.S., Han X., Richard J. Auchus, Saunders T.L., Smith G.D.Fuentes:scopusMetabolic, reproductive, and neurologic abnormalities in Agpat1-Null Mice
ArticleAbstract: Defects in the biosynthesis of phospholipids and neutral lipids are associated with cell membrane dyPalabras claves:Autores:Agarwal A.K., Dalal J., Garg A., Hamra F., Nagamma S., Richard J. Auchus, Sankella S., Shao X., Tunison K.Fuentes:scopus