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Analysis of HFE gene mutations (C282Y, H63D, and S65C) in the Ecuadorian population
ArticleAbstract: Type 1 hemochromatosis is a disorder of iron metabolism mostly related to the HFE gene mutations. InPalabras claves:C282Y, ECUADOR, H63D, HFE gene, S65C, Type 1 hemochromatosisAutores:Cesar Paz-y-Miño, Collantes J.C., Giménez P., Juan Carlos Collantes, Paola E. LeoneFuentes:googlescopusA novel CRISPR/RNA-aptamer-mediated base editing system with potential therapeutic value
OtherAbstract: Description Nuclease-dependent precise genome editing such as correction of point mutations requiresPalabras claves:Autores:Juan Carlos CollantesFuentes:googleDevelopment and Characterization of a modular CRISPR and RNA aptamer mediated base editing system
OtherAbstract: Conventional CRISPR approaches for precision genome editing rely on the introduction of DNA double-sPalabras claves:Autores:Juan Carlos CollantesFuentes:googleCCR5∆ 32, CCR2-64I, and SDFI-3'A Polymorphisms Related to Resistance to HIV-1 Infection and Disease in the Ecuadorian Population
OtherAbstract: The aim of this study was to determine the alíele frequencies of genetic variants CCR5∆32, CCR2-64I,Palabras claves:Autores:Cesar Paz-y-Miño, Juan Carlos CollantesFuentes:googleEffect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer
OtherAbstract: Metabolism of cancer cells is characterized by aerobic glycolysis, or the Warburg effect. Aerobic glPalabras claves:Autores:Juan Carlos CollantesFuentes:googleNuclease-independent targeted gene editing platform and uses thereof
OtherAbstract: Larson et al:“CRISPR interference (CRISPRi) for sequence specific control of gene expression”, Nat.Palabras claves:Autores:Juan Carlos CollantesFuentes:googleHighly Efficient DNA Base Editors Mediated By RNA-Aptamer Recruitment For Targeted Genome Modification And Uses Thereof
OtherAbstract: CZPWVGJYEJSRLH-UHFFFAOYSA-N 289-95-2 Chemical compound data: image/svg+xml; base64, PD94bWwgdmVyc2lvPalabras claves:Autores:Juan Carlos CollantesFuentes:googleMitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models
OtherAbstract: Pancreatic ductal adenocarcinoma (PDA) is aggressive cancer characterized by rapid progression, metaPalabras claves:Autores:Juan Carlos CollantesFuentes:googleTargeted gene editing platform independent of dna double strand break and uses thereof
OtherAbstract: CZPWVGJYEJSRLH-UHFFFAOYSA-N 289-95-2 Chemical compound data: image/svg+xml; base64, PD94bWwgdmVyc2lvPalabras claves:Autores:Juan Carlos CollantesFuentes:google