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Crystal Structures of Staphylococcus aureus Ketol-Acid Reductoisomerase in Complex with Two Transition State Analogues that Have Biocidal Activity
ArticleAbstract: Ketol-acid reductoisomerase (KARI) is an NAD(P)H and Mg2+-dependent enzyme of the branched-chain amiPalabras claves:branched-chain amino acid biosynthesis, Drug Discovery, Herbicide, ketol-acid reductoisomerase, transition state analogueAutores:David A. Terán, Guddat L.W., Kandale A., Lv Y., Mario Daniel García, McGeary R.P., Patel K.M., Schembri M.A., Schenk G., Zheng S.Fuentes:scopusDegradation of PET Bottles by an Engineered Ideonella sakaiensis PETase
ArticleAbstract: Extensive plastic production has become a serious environmental and health problem due to the lack oPalabras claves:biodegradation, enzyme engineering, IsPETase, Pet, Polyethylene terephthalateAutores:Debut Alexis, Karla Sofía Vizuete Armendáriz, Karla Vizuete, Liliana A. Cerda-Mejía, Maria Eduarda Sevilla, Mario D. Garcia, Mario Daniel García, Santiago Casado, Vinicio Danilo Armijos-Jaramillo, Yunierkis Perez-CastilloFuentes:googlescopusTriazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads
ArticleAbstract: Aspergillus fumigatus is a fungal pathogen whose effects can be debilitating and potentially fatal iPalabras claves:Autores:Fraser J.A., Guddat L.W., Lonhienne T., Low Y.S., Mario D. Garcia, Mario Daniel García, Schenk G.Fuentes:googlescopus