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Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections
ArticleAbstract: The increased prevalence of drug-resistant human pathogenic fungal diseases poses a major threat toPalabras claves:acetohydroxyacid synthase, Antifungal drug, Candida Albicans, Crystal structure, HerbicideAutores:Agnew-Francis K., Chua S.M.H., Fraser J.A., Guddat L.W., Lee Y.T., Lonhienne T., Low Y.S., Mario D. Garcia, Mario Daniel García, Nouwens A., Wang J.G., Williams C.M.Fuentes:googlescopusIdentification of inhibitors of the RdRp and Mpro enzymes of SARS-CoV-2 virus by structural homology
ArticleAbstract: TCOVID-19 has enormously impacted global public health due to the high infection and mortality ratesPalabras claves:covid-19, Inhibitors, Mpro, RdRp, SARS-COV-2Autores:Chico-Terán F., Espín-Sánchez D., Jaramillo-Guapisaca K., Liliana A. Cerda-Mejía, Mario Daniel García, Ramos-Aristimbay M.L., Sánchez-Vaca A.S., Vizueta-Rubio C.Fuentes:scopusStructural basis of resistance to herbicides that target acetohydroxyacid synthase
ArticleAbstract: Acetohydroxyacid synthase (AHAS) is the target for more than 50 commercial herbicides; first appliedPalabras claves:Autores:Cheng Y., Guddat L.W., Hu S.H., Lonhienne T., Low Y.S., Mario D. Garcia, Mario Daniel García, Schenk G., Williams C.M.Fuentes:googlescopusTriazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads
ArticleAbstract: Aspergillus fumigatus is a fungal pathogen whose effects can be debilitating and potentially fatal iPalabras claves:Autores:Fraser J.A., Guddat L.W., Lonhienne T., Low Y.S., Mario D. Garcia, Mario Daniel García, Schenk G.Fuentes:googlescopus