Mostrando 10 resultados de: 46
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Biochemical and Biophysical Research Communications(6)
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Characterization of the A<inf>2A</inf>R-D<inf>2</inf>R interface: Focus on the role of the C-terminal tail and the transmembrane helices
ArticleAbstract: A single serine point mutation (S374A) in the adenosine A2A receptor (A2AR) C-terminal tail reducesPalabras claves:Adenosine A receptor 2A, Dopamine D receptor 2, G protein coupled receptors, Heteromerization, Protein-protein interaction, Transmembrane segmentsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Corrales F., Flajolet M., Frankowska M., Fuxe K., Gómez-Soler M., Heintz N., Marcellino D., Narváez M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusCo-immunoprecipitation of Membrane-Bound Receptors from Subsynaptic Compartments
Book PartAbstract: The allosteric modulation in G protein-coupled heteroreceptors have opened a new vision of the physiPalabras claves:Co-immunoprecipitation, G protein-coupled receptors, Heteroreceptors, Receptor-receptor interaction, Subcellular fractionation, Sucrose gradient, Synaptic compartments, SynaptosomeAutores:María García-Barceló, W. Romero-Fernandez, Yunys Pérez-BetancourtFuentes:scopusBiophysical evidences for receptor heteromer formation between the oxitocin and the serotonin 1A receptors
ArticleAbstract: Currently, it is considered that both, the formation of homodimers and heterodimers and the allosterPalabras claves:anxiety, Depression, Heteromer, Heteroreceptor, Oxytocin receptor, Serotonin 1A receptorAutores:Andres Tayo-Montenegro, Cristian Carvajal-Tapia, Israel Manjarrés-Raza, María García-Barceló, W. Romero-Fernandez, Yunys Pérez-BetancourtFuentes:scopusA2AR transmembrane 2 peptide administration disrupts the A2AR-A2AR homoreceptor but not the A2AR-D2R heteroreceptor complex: Lack of actions on rodent cocaine self-administration
ArticleAbstract: It was previously demonstrated that rat adenosine A2AR transmembrane V peptide administration into tPalabras claves:Adenosine A2A receptor, Allosteric receptor–receptor interactions, cocaine use disorder, dopamine D2 receptor, Heteroreceptor complexes, Homoreceptor complexes, Small interfering peptides: G protein-coupled receptorsAutores:Borroto-Escuela D.O., Filip M., Frankowska M., Fuxe K., W. Romero-Fernandez, Wydra K., Zhou Z.Fuentes:scopusConventional culture media enriched with extracts of quinoa, amaranth and chia promotes the Staphylococcus aureus growth
ArticleAbstract: Increasing the bacterial growth rate reduces the time getting the bacteria identification. This is hPalabras claves:Amaranthus Caudatus, Bacterial growth, CHENOPODIUM QUINOA, Salvia hispanica, STAPHYLOCOCCUS AUREUSAutores:Cristian Carvajal-Tapia, Elizabeth Proaño-Pérez, Israel Manjarrés-Raza, W. Romero-FernandezFuentes:scopusCRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
ArticleAbstract: Astrocytes become reactive in response to insults to the central nervous system by adopting context-Palabras claves:Autores:Ao Y., Fancy S.P.J., Goate A., Kampmann M., Kim H., Koontz M., Krawczyk M., Leng K., Li E., Lippmann E.S., Rooney B., Rose I.V.L., Schrag M.S., Sofroniew M.V., Tcw J., Ullian E.M., W. Romero-Fernandez, Wang S., Xia W., Zhang Y.Fuentes:scopusAcute Cocaine Enhances Dopamine D<inf>2</inf>R Recognition and Signaling and Counteracts D<inf>2</inf>R Internalization in Sigma1R-D<inf>2</inf>R Heteroreceptor Complexes
ArticleAbstract: The current study was performed to establish the actions of nanomolar concentrations of cocaine, notPalabras claves:Cocaine, dimerization, dopamine D2 receptor, Heteroreceptor complexes, Oligomerization, Sigma 1 receptor, Substance use disorderAutores:Beggiato S., Borroto-Escuela D.O., Ferraro L., Filip M., Fuxe K., Narváez M., Pinton L., Tanganelli S., W. Romero-Fernandez, Wydra K.Fuentes:scopusAcute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor–receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels
ArticleAbstract: Background: Antagonistic adenosine A2A receptor (A2AR)-dopamine D2 receptor (D2R) receptor–receptorPalabras claves:Adenosine A2A receptor, Cocaine, dopamine D2 receptor, Heteroreceptor complexes, Sigma1 receptorAutores:Beggiato S., Borroto-Escuela D.O., Ferraro L., Filip M., Fuxe K., Tanganelli S., W. Romero-Fernandez, Wydra K., Zhou Z.Fuentes:scopusAgonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family
ArticleAbstract: Fibroblast growth factor receptor 1 (FGFR1) is known to be activated by homodimerization in the presPalabras claves:BRET, FGFR1, Fibroblast growth factors, Homodimerization, MAPKAutores:Agnati L.F., Belluardo N., Borroto-Escuela D.O., Ciruela F., Fuxe K., Mudó G., Narváez M., Pérez-Alea M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusAltered trafficking and unfolded protein response induction as a result of M <inf>3</inf> muscarinic receptor impaired N-glycosylation
ArticleAbstract: The human M 3 muscarinic acetylcholine receptor is present in both the central and peripheral nervouPalabras claves:apoptosis, Endoplasmic reticulum stress, Muscarinic receptor, N-glycosylation, unfolded protein responseAutores:Borroto-Escuela D.O., Garcia-Mesa Y., Garriga P., Pérez-Alea M., W. Romero-FernandezFuentes:scopus