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Biochemical and Biophysical Research Communications(1)
Current Protein and Peptide Science(1)
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scopus(6)
A2AR transmembrane 2 peptide administration disrupts the A2AR-A2AR homoreceptor but not the A2AR-D2R heteroreceptor complex: Lack of actions on rodent cocaine self-administration
ArticleAbstract: It was previously demonstrated that rat adenosine A2AR transmembrane V peptide administration into tPalabras claves:Adenosine A2A receptor, Allosteric receptor–receptor interactions, cocaine use disorder, dopamine D2 receptor, Heteroreceptor complexes, Homoreceptor complexes, Small interfering peptides: G protein-coupled receptorsAutores:Borroto-Escuela D.O., Filip M., Frankowska M., Fuxe K., W. Romero-Fernandez, Wydra K., Zhou Z.Fuentes:scopusAcute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor–receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels
ArticleAbstract: Background: Antagonistic adenosine A2A receptor (A2AR)-dopamine D2 receptor (D2R) receptor–receptorPalabras claves:Adenosine A2A receptor, Cocaine, dopamine D2 receptor, Heteroreceptor complexes, Sigma1 receptorAutores:Beggiato S., Borroto-Escuela D.O., Ferraro L., Filip M., Fuxe K., Tanganelli S., W. Romero-Fernandez, Wydra K., Zhou Z.Fuentes:scopusG-protein-coupled receptors oligomerization: Emerging signaling units and new opportunities for drug design
ArticleAbstract: G-protein-coupled receptors (GPCRs) are a widespread family of transmembrane receptors with differenPalabras claves:Dimers, disease, drug design, G-protein-coupled receptors, ligand, OligomerizationAutores:Borroto-Escuela D.O., Fuxe K., Garriga P., Ramon E., Rivera D., Tena-Campos M., W. Romero-FernandezFuentes:scopusDopamine D2 and 5-hydroxytryptamine 5-HT<inf>2A</inf> receptors assemble into functionally interacting heteromers
ArticleAbstract: In view of the co-distribution of dopamine D2LR and 5-hydroxytryptamine 5-HT2A receptors (D2LR and 5Palabras claves:allosteric modulation, Dopamine D R receptor 2, G protein-coupled receptors, Heteromerization, protein-protein interactions, Serotonin 5-HT receptor 2AAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Marcellino D., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: Novel targets for antipsychotic drugs
Book PartAbstract: This review is focused on the D2 heteroreceptor complexes within the ventral striatum with their recPalabras claves:D2 receptors, Heteroreceptor complexes, Receptor-receptor interactions, Schizophrenia, Ventral striatumAutores:Agnati L.F., Borroto-Escuela D.O., Di Palma M., Ferraro L., Fuxe K., Pérez-Alea M., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusOn the existence of a possible A<inf>2A</inf>-D<inf>2</inf>-β- arrestin2 complex: A<inf>2A</inf> agonist modulation of D<inf>2</inf> agonist-induced β-arrestin2 recruitment
ArticleAbstract: Given that coactivation of adenosine A2A (A2AR) and dopamine D2 (D2R) receptors results in the coaggPalabras claves:allosteric modulation, G-protein-coupled receptors, Heteromerization, Internalization, receptor-protein interactionAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Tarakanov A.O., W. Romero-FernandezFuentes:scopus