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Characterization of antimicrobial, antioxidant, and leishmanicidal activities of Schiff base derivatives of 4-aminoantipyrine
ArticleAbstract: Our main interest is the characterization of compounds to support the development of alternatives toPalabras claves:antimicrobial activity, Cytotoxicity, LEISHMANIA, Schiff base synthesisAutores:Ana Maria Poveda, Araya-Maturana R., Beske T., Jessica Mora, Jorge Hebkp_redia-Moya, Jorge Pérez-Barrera, Lizeth Dobronski, Olalla Barreiro-Costa, Patricio Rojas-Silva, Rommel Guevara, rommy TeranFuentes:scopusEvaluation of the Anti-Leishmania mexicana and -Trypanosoma brucei Activity and Mode of Action of 4,4′-(Arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)
ArticleAbstract: Trypanosomiasis and leishmaniasis are neglected infections caused by trypanosomatid parasites. The fPalabras claves:4,4′-(arylmethylene)bis(1H-pyrazol-5-ols), Adme, drug-like, LEISHMANIA, redox biosensor, TrypanosomaAutores:Comini M.A., Erika B. Muñoz, Jorge Hebkp_redia-Moya, Medeiros A., Olalla Barreiro-Costa, Patricio Rojas-Silva, Quiroga Lozano C.Fuentes:scopusDifferent role of cAMP pathway on the human mast cells HMC-1<sup>560</sup> and HMC-1<sup>560,816</sup> activation
ArticleAbstract: HMC-1 are inflammatory cells that release vasoactive substances such as histamine. These cells havePalabras claves:c- KIT RECEPTOR, cAMP/PKA/ PATHWAY, DASATINIB, HMC-1, IMATINIB, MAST CELLSAutores:Alfonso A., Botana L.M., Olalla Barreiro-Costa, Tobío A.Fuentes:scopusSynthesis and evaluation of biological activities of bis(Spiropyrazolone)cyclopropanes: A potential application against Leishmaniasis
ArticleAbstract: This work focuses on the search and development of drugs that may become new alternatives to the comPalabras claves:Adme, Bis(spiropyrazolone)cyclopropanes, drugs, Leishmaniasis cytotoxicityAutores:Ana Herrera, Ana Maria Poveda, Cristina Cueva, Eliana Lara-Barba, Gabriela Morales-Noboa, Javier Santamaría-Aguirre, Jorge Hebkp_redia-Moya, Juan Carlos Romero-Benavides, Natalia Bailon-Moscoso, Olalla Barreiro-Costa, Patricio Rojas-Silva, Ron-Garrido L.Fuentes:scopus