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Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates
ArticleAbstract: The cytochrome P450 family 1 enzymes (CYP1s) are a diverse family of hemoprotein monooxygenases, whiPalabras claves:ancestral sequence reconstruction, CYP1A2, CYP1B1, Cytochrome p450, drug metabolism, thermostabilityAutores:Andersson S., Boden M., Foley G., Gillam E.M.J., Gumulya Y., Harris K.L., Janosik T., Jurva U., Sandinge A.S., Saskya E. Carrera-Pacheco, Syed P., Thomson R.E.S.Fuentes:scopusLight and heat-shock mediated TDA1 overexpression as a tool for controlled high-yield recombinant protein production in Chlamydomonas reinhardtii chloroplasts
ArticleAbstract: The microalga Chlamydomonas reinhardtii offers a rapid, scalable and low-cost platform for recombinaPalabras claves:Chloroplast, Heat-shock, Inducible, Light, microalgae, RecombinantAutores:Hankamer B., Oey M., Saskya Carrera, Saskya E. Carrera-PachecoFuentes:googlescopus