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International Journal of Molecular Sciences(1)
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Chemosensitizing activity of Cuban propolis and nemorosone in doxorubicin resistant human colon carcinoma cells
ArticleAbstract: Propolis is a natural product obtained from bees, used since ancient times for its multiple pharmacoPalabras claves:Chemosensitization, Colorectal cancer, Combination chemotherapy, nemorosone, propolisAutores:Carrara M., Díaz-García A., Frión-herrera Y., Gabbia D., Osmany Cuesta-RubioFuentes:googlescopusAntiproliferative activity of brown cuban propolis extract on human breast cancer cells
ArticleAbstract: Brown Cuban propolis (BCP) is the major type of propolis in Cuba; its chemical composition is exclusPalabras claves:Breast Cancer, Brown cuban propolis, Cytotoxicity, MCF-7Autores:Morello S., Osmany Cuesta-Rubio, Piccinelli L.A., Pinto A., Popolo A., Rastrelli L., Sorrentino R.Fuentes:googlescopusCuban brown propolis interferes in the crosstalk between colorectal cancer cells and m2 macrophages
ArticleAbstract: Tumor-associated macrophages (TAMs), primarily the M2 phenotype, are involved in the progression andPalabras claves:Colorectal cancer, Epithelial– mesenchymal transition, nemorosone, propolis, Tumor-associated macrophagesAutores:Carrara M., De Martin S., Frión-herrera Y., Gabbia D., Osmany Cuesta-Rubio, Scaffidi M., Zagni L.Fuentes:googlescopusEFFECT OF MITOCHONDRIAL UNCOUPLER 2, 4-DINITROPHENOL ON THE GROWTH OF TRANSPLANTABLE ADENOCARCINOMA OF MAMMARY GLAND OF MICE CA755
OtherAbstract: EFFECT OF MITOCHONDRIAL UNCOUPLER 2,4-DINITROPHENOL ON THE GROWTH OF TRANSPLANTABLE ADENOCARCINOMA OPalabras claves:Autores:Osmany Cuesta-RubioFuentes:googleEffects of nemorosone, isolated from the plant Clusia rosea, on the cell cycle and gene expression in MCF-7 BUS breast cancer cell lines
ArticleAbstract: Background: Breast cancer is the cause of considerable morbidity and mortality in women. While estroPalabras claves:Breast Cancer, cell cycle, Clusia rosea, Gene Expression, nemorosoneAutores:Camargo M.S., Espanha L., Nogueira C., Oliveira M., Oliveira-Höhne A., Osmany Cuesta-Rubio, Resende F.A., Santoni M., Varanda E.A., Vilegas W.Fuentes:scopusEl agente anticancerígeno nemorosona, es un nuevo y potente desacoplador protonofórico mitocondrial.
OtherAbstract: La nemorosona, un acilfloroglucinol policíclico y poliprenilado de origen natural, ha recibido una cPalabras claves:Autores:Osmany Cuesta-RubioFuentes:googleNemorosone inhibits the proliferation and migration of hepatocellular carcinoma cells
ArticleAbstract: Aims: In the tumor microenvironment, dysregulated immune cells could promote tumor progression, invaPalabras claves:hepatocellular carcinoma, Human monocytic THP-1 cells, nemorosone, propolis, Tumor microenvironment (TME), Tumor-associated macrophages (TAMs)Autores:Carrara M., De Martin S., Frión-herrera Y., Gabbia D., Osmany Cuesta-RubioFuentes:googlescopusThe anti-cancer agent guttiferone-A permeabilizes mitochondrial membrane: Ensuing energetic and oxidative stress implications
ArticleAbstract: Guttiferone-A (GA) is a natural occurring polyisoprenylated benzophenone with cytotoxic action in viPalabras claves:Anti-cancer action, Guttiferone-A, HepG2 cells, Mitochondria, Mitochondrial membrane permeabilization, Oxidative Stress, UncouplingAutores:Alberici L.C., Curti C., Leopoldino A.M., Núñez-Figueredo Y., Osmany Cuesta-Rubio, Pardo-Andreu G.L., Pestana C.R., Rodrigues F.P., Tudella V.G., Uyemura S.A.Fuentes:googlescopusThe anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler
ArticleAbstract: Nemorosone, a natural-occurring polycyclic polyprenylated acylphloroglucinol, has received increasinPalabras claves:Cáncer, HepG2 cell death, Mitochondria, nemorosone, Protonophore, UncouplerAutores:Alberici L.C., Curti C., Leopoldino A.M., Núñez-Figueredo Y., Osmany Cuesta-Rubio, Pardo-Andreu G.L., Pestana C.R., Rodrigues F.P., Tudella V.G., Uyemura S.A.Fuentes:googlescopusThe cuban propolis component nemorosone inhibits proliferation and metastatic properties of human colorectal cancer cells
ArticleAbstract: The majority of deaths related to colorectal cancer (CRC) are associated with the metastatic processPalabras claves:Apoptosis cell death, Colorectal cancer, Epithelial, Mesenchymal transition, nemorosone, propolisAutores:Carrara M., De Martin S., Frión-herrera Y., Gabbia D., Osmany Cuesta-Rubio, Scaffidi M., Zagni L.Fuentes:googlescopus