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Cytotoxic Property of Grias neuberthii Extract on Human Colon Cancer Cells: A Crucial Role of Autophagy
ArticleAbstract: Traditional herbal medicine has become an important alternative in the treatment of various cancer tPalabras claves:Autores:Alírica Isabel Suárez, Jimmy Samaniego-Romero, Juan Carlos Romero-Benavides, Luis Miguel Guamán Ortíz, Natalia Bailon-Moscoso, Ortiz-Diaz K., Paola Castillo-Veintimilla, Stephania Torres-AguilarFuentes:scopusCytotoxic activity of seco-entkaurenes from Croton caracasana on human cancer cell lines
ArticleAbstract: In the course of searching for bioactive compounds from Croton species from Venezuela, two seco-entkPalabras claves:Croton caracasana, Cytotoxic, euphorbiaceae, seco-entkaurenesAutores:Alírica Isabel Suárez, Arvelo F.A., Chavez K., Compagnone R.S., de Sanctis J.B., Mateu E., Mijares M.R., Muñoz A., Sojo F.J.Fuentes:scopusCytotoxic effects of fisturalin-3 and 11-Deoxyfisturalin-3 on Jurkat and U937 cell lines
ArticleAbstract: Background. Fisturalines are bromotyrosine compounds isolated from marine sponges. Previous studiesPalabras claves:11-deoxyfistularin-3, Aplysina fistularis, Bromotyrosine, Cáncer, Fistularin-3, Leukemia, quercetinAutores:Alírica Isabel Suárez, Avila R., Barroeta A., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R., Ochoa M.Fuentes:scopusCytotoxic effects of the monomer and dimer of 3, 4-seco-ent-kaurene from Croton micans and their interaction with antitumoral drugs on cellular line of human prostate cancer
ArticleAbstract: The cytotoxic activity of two bioactive molecules obtained from Croton species, caracasine acid (monPalabras claves:Combination index, Croton micans, Dimer, Monomer, Prostate cancer, Seco-ent-kaurene, synergism, Tumor therapyAutores:Alírica Isabel Suárez, Arvelo F.A., Chavez K., Sojo F.J., Vivas J.Fuentes:scopusCaracasine acid, an ent-3,4-seco-kaurene, promotes apoptosis and cell differentiation through NFkB signal pathway inhibition in leukemia cells.
ArticleAbstract: Caracasine acid (CA) is an ent-3,4-seco-kaurene isolated from the plant Croton micans. Decreased canPalabras claves:Annexin-V, apoptosis, Cáncer, Caracasine acid, Croton, Kaurene compounds, Leukemia, NF-κBAutores:Alírica Isabel Suárez, Chavez K., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R.Fuentes:scopusDronedarone, an amiodarone analog with improved anti-Leishmania mexicana efficacy
ArticleAbstract: Dronedarone and amiodarone are cationic lipophilic benzofurans used to treat cardiac arrhythmias. ThPalabras claves:Autores:Alírica Isabel Suárez, Benaím G., Casanova P., Concepcion J.L., Hernández-Rodríguez V., Liu Y.L., Mujica-Gonzalez S., Oldfield E., Pániz-Mondolfi A.E., Parra-Gimenez N., Plaza-Rojas L.Fuentes:scopusOnoseriolide, from Hedyosmum racemosum, induces cytotoxicity and apoptosis in human colon cancer cells
ArticleAbstract: The number of colon cancer patients is increasing, and new alternatives for treatment are important.Palabras claves:apoptosis, Autophagy, Colon cancer, Cytotoxicity, Hedyosmum racemosum, onoseriolideAutores:Alírica Isabel Suárez, Daisy Vega-Ojeda, Fernando Gordillo, Luis Guaman, Luis Miguel Guamán Ortíz, Natalia Bailon-Moscoso, Vladimir MorochoFuentes:googlescopusThe marine sponge toxin agelasine B increases the intracellular Ca <sup>2+</sup> concentration and induces apoptosis in human breast cancer cells (MCF-7)
ArticleAbstract: Purpose: In search for new drugs derived from natural products for the possible treatment of cancer,Palabras claves:Agelasine B, calcium, Natural products, SERCA, ThapsigarginAutores:Alírica Isabel Suárez, Arvelo F.A., Benaím G., Chirino P., Colman L., Compagnone R.S., de Sanctis J.B., Dipolo R., Felibertt P., Galindo-Castro I., Mayora A., Pimentel A.A., Rojas H., Silva M.L., Sojo F.J.Fuentes:scopusThe role of the glycosyl moiety of myricetin derivatives in anti-HIV-1 activity in vitro
ArticleAbstract: Background: Plant extracts are sources of valuable compounds with biological activity, especially foPalabras claves:flavonoids, Glycosyl flavonoids, HIV RT docking, HIV-1, Myricetin, Reverse transcriptaseAutores:Alírica Isabel Suárez, Baptista J., Ortega J.T., Pujol F.H., Rangel H.R., Serrano M.L.Fuentes:scopus