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Human skin permeation studies with PPARγ agonist to improve its permeability and efficacy in inflammatory processes
ArticleAbstract: Rosacea is the most common inflammatory skin disease. It is characterized by erythema, inflammatoryPalabras claves:inflammation, limonene, Pioglitazone, PPAR-γ, ROSÁCEA, Skin permeationAutores:Calpena A.C., Espina M., Fábrega M.J., García M.L., Lupe Carolina Espinoza, Rodríguez-Lagunas M.J., Silva-Abreu M.Fuentes:scopusEnhanced transdermal delivery of pranoprofen using a thermo-reversible hydrogel loaded with lipid nanocarriers for the treatment of local inflammation
ArticleAbstract: A biocompatible topical thermo-reversible hydrogel containing Pranoprofen (PF)-loaded nanostructuredPalabras claves:inflammation, nanostructured lipid carriers, Pranoprofen, Thermo-reversible hydrogel, Transdermal deliveryAutores:Calpena A.C., Colom H., Lupe Carolina Espinoza, Rincón M., Rodríguez-Lagunas M.J., Silva-Abreu M., Sosa L.Fuentes:scopusFormulation strategies to improve nose-to-brain delivery of donepezil
ArticleAbstract: Donepezil (DPZ) is widely used in the treatment of Alzheimer’s disease in tablet form for oral adminPalabras claves:Alzheimer’s disease, Donepezil, Mucoadhesion, NANOEMULSIÓN, Nose-to-brain, Pluronic F-127Autores:Calpena A.C., Cañas M.A., Clares-Naveros B., Halbaut L., Lupe Carolina Espinoza, Rodríguez-Lagunas M.J., Silva-Abreu M.Fuentes:scopusGel Formulations with an Echinocandin for Cutaneous Candidiasis: The Influence of Azone and Transcutol on Biopharmaceutical Features
ArticleAbstract: Caspofungin is a drug that is used for fungal infections that are difficult to treat, including invaPalabras claves:Azone, Candidiasis, caspofungin, echinocandin, gel, permeation enhancerAutores:Bozal-de Febrer N., Calpena A.C., Clares-Naveros B., Lupe Carolina Espinoza, Mallandrich M., Pérez-González N., Rincón M., Sosa L., Suñer-Carbó J.Fuentes:scopusEffect of Penetration Enhancers and Safety on the Transdermal Delivery of Apremilast in Skin
ArticleAbstract: The poor water solubility of apremilast (APR) is the main impediment to the penetration of the drugPalabras claves:Apremilast, Promoter, Skin, squaleneAutores:Alvarado H., Baldomá L., Calpena A.C., Díaz-Garrido N., Lupe Carolina Espinoza, Paulo Sarango-Granda, Rodríguez-Lagunas M.J.Fuentes:scopusDevelopment of a nasal donepezil-loaded microemulsion for the treatment of Alzheimer’s disease: In vitro and Ex vivo characterization
ArticleAbstract: Background: Donepezil (DPZ) is widely prescribed as a specific and reversible acetylcholinesterase iPalabras claves:Alzheimer’s disease, Delivery systems, Donepezil, Intranasal route, Microemulsion, permeationAutores:Calpena A.C., Clares-Naveros B., Fábrega M.J., García M.L., Lupe Carolina Espinoza, Vacacela M.Fuentes:scopusDevelopment of a topical amphotericin b and bursera graveolens essential oil-loaded gel for the treatment of dermal candidiasis
ArticleAbstract: The higher molecular weight and low solubility of amphotericin B (AmB) hinders its topical administrPalabras claves:Amphotericin B, Bursera graveolens, Candidiasis, Essential oil, gel, Topical treatmentAutores:Bozal N., Calpena A.C., Chulca-Torres B., Díaz-Garrido N., Granda P.C., Lupe Carolina Espinoza, Sosa L.Fuentes:scopusCharacterization and In Vivo Anti-Inflammatory Efficacy of Copal (Dacryodes peruviana (Loes.) H.J. Lam) Essential Oil
ArticleAbstract: Essential oils are natural aromatic substances that contain complex mixtures of many volatile compouPalabras claves:Dacryodes peruviana, Essential oil, inflammation, limonene, Α-phellandreneAutores:Calpena A.C., Eduardo Valarezo, Fábrega M.J., Lupe Carolina Espinoza, Mallandrich M., Rodríguez-Lagunas M.J., Sosa L.Fuentes:scopusComparative Study of Donepezil-Loaded Formulations for the Treatment of Alzheimer’s Disease by Nasal Administration
ArticleAbstract: Alzheimer’s disease is characterized by a progressive deterioration of neurons resulting in a steadyPalabras claves:Alzheimer’s disease, Donepezil, gel, intranasal administrationAutores:Brito-Llera A., Calpena A.C., Diana Guaya, Halbaut L., Lupe Carolina Espinoza, Mallandrich M., Perotti R.M., Sosa L.Fuentes:scopusComparative study of Ex Vivo transmucosal permeation of pioglitazone nanoparticles for the treatment of Alzheimer's disease
ArticleAbstract: Pioglitazone has been reported in the literature to have a substantial role in the improvement of ovPalabras claves:Alzheimer's disease, Nanoparticles, Pioglitazone, PLGA-PEG, Transmucosal permeationsAutores:Calpena A.C., Espina M., García M.L., Halbaut L., Lupe Carolina Espinoza, Silva-Abreu M.Fuentes:scopus