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Anticancer Agent Edelfosine Exhibits a High Affinity for Cholesterol and Disorganizes Liquid-Ordered Membrane Structures
ArticleAbstract: Edelfosine is an anticancer drug with an asymmetric structure because, being a derivative of glyceroPalabras claves:Autores:Alessio Ausili, Corbalán-García S., De Godos A., Gómez-Murcia V., Gómez‐Fernández J.C., Martínez-Valera P., Teruel J.A., Torrecillas A.Fuentes:googlescopusCapsaicin Fluidifies the Membrane and Localizes Itself near the Lipid-Water Interface
ArticleAbstract: Capsaicin is the chemical responsible for making some peppers spicy hot, but additionally it is usedPalabras claves:1 H NOESY MAS NMR, 2 H NMR, Capsaicin, dsc, membranes, SAXD, WAXDAutores:A Ausili, Alessio Ausili, Corbalán-García S., De Godos A., Fernández-Martínez A., Gómez‐Fernández J.C., Schneider M., Torrecillas A.Fuentes:googlerraaescopusHigh hydrostatic pressure-induced conformational changes in protein disulfide oxidoreductase from the hyperthermophilic archaeon pyrococcus furiosus. A fourier-transform infrared spectroscopic study
ArticleAbstract: Protein disulfide oxidoreductases (PDOs) are ubiquitous redox enzymes that catalyse dithiol-disulfidPalabras claves:Autores:Alessio Ausili, Baldassarre M., Bartolucci S., Bertoli E., Pedone E., Saviano M., Scirè A., Tanfani F.Fuentes:googlescopusMink growth hormone structural-functional relationships: Effects of renaturing and storage conditions
ArticleAbstract: Fourier-transform infrared spectroscopy, in vitro bioassay and enzyme-linked immunoassay were used tPalabras claves:biological activity, Fourier-transform infrared spectroscopy, Freeze-drying, Immunological activity, Mink growth hormoneAutores:Alessio Ausili, Borromeo V., Bumelis V.A., D’auria S., Scirè A., Secchi C., Sereikaite J., Tanfani F.Fuentes:googlescopusPhenolic Group of α-Tocopherol Anchors at the Lipid-Water Interface of Fully Saturated Membranes
ArticleAbstract: α-Tocopherol is considered to carry on a very important role as an antioxidant for membranes and lipPalabras claves:Autores:Alessio Ausili, Corbalán-García S., De Godos A., Gómez‐Fernández J.C., Torrecillas A.Fuentes:googlescopusThe increase in positively charged residues in cecropin D-like Galleria mellonella favors its interaction with membrane models that imitate bacterial membranes
ArticleAbstract: A comparative study of three synthetic peptides, namely neutral Cecropin D-like G. mellonella (WT) aPalabras claves:Antimicrobial peptide, calorimetry, Cationic charge, Galleria mellonella, Infrared spectroscopy, Peptide-membrane interactionsAutores:Alessio Ausili, Aranda F.J., Gómez‐Fernández J.C., Manrique-Moreno M., Oñate-Garzón J., Patiño E., Torrecillas A.Fuentes:googlescopusThe interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids
ArticleAbstract: The C-terminal domain of the pro-apoptotic protein Bax (Bax-C) is supposed to act as a membrane anchPalabras claves:13 C-NMR, 31 P-NMR, apoptosis, BAX, MAS-NMR, Protein-lipid interactionAutores:Alessio Ausili, Corbalán-García S., De Godos A., Gómez‐Fernández J.C., Torrecillas A.Fuentes:googlescopus