Mostrando 10 resultados de: 41
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Archives of Biochemistry and Biophysics(4)
Biochimica et Biophysica Acta - Biomembranes(4)
Biomolecules(3)
Journal of Physical Chemistry B(3)
Langmuir(3)
Clotrimazole fluidizes phospholipid membranes and localizes at the hydrophobic part near the polar part of the membrane
ArticleAbstract: Clotrimazole (1‐[(2‐chlorophenyl)‐diphenylmethyl]‐imidazole) is an azole antifungal drug belonging tPalabras claves:Clotrimazole, Location, Membrane fluidity, Model membraneAutores:Alessio Ausili, Gómez‐Fernández J.C., Teruel J.A., Yakymenko I.Fuentes:googlescopusBinding of glucose to the D-galactose/D-glucose-binding protein from Escherichia coli restores the native protein secondary structure and thermostability that are lost upon calcium depletion
ArticleAbstract: The effect of the depletion of calcium on the structure and thermal stability of the D-galactose/D-gPalabras claves:Galactose/glucose-binding protein, Infrared spectroscopy, Protein stability, Protein structureAutores:Alessio Ausili, Bertoli E., D’auria S., Marabotti A., Rossi M., Scognamiglio V., Staiano M., Tanfani F., Varriale A.Fuentes:googlescopusBinding of glutamine to glutamine-binding protein from Escherichia coli induces changes in protein structure and increases protein stability
ArticleAbstract: Glutamine-binding protein (Gl-nBP) from Escherichia coli is a monomeric protein localized in the perPalabras claves:2D-IR correlation analysis, FTIR, Glutamine-binding protein, Infrared, Protein structure, thermostabilityAutores:Alessio Ausili, D’auria S., Marabotti A., Rossi M., Scirè A., Scognamiglio V., Staiano M., Tanfani F., Varriale A.Fuentes:googlescopusAnticancer Agent Edelfosine Exhibits a High Affinity for Cholesterol and Disorganizes Liquid-Ordered Membrane Structures
ArticleAbstract: Edelfosine is an anticancer drug with an asymmetric structure because, being a derivative of glyceroPalabras claves:Autores:Alessio Ausili, Corbalán-García S., De Godos A., Gómez-Murcia V., Gómez‐Fernández J.C., Martínez-Valera P., Teruel J.A., Torrecillas A.Fuentes:googlescopusA comparative infrared spectroscopic study of glycoside hydrolases from extremophilic archaea revealed different molecular mechanisms of adaptation to high temperatures
ArticleAbstract: The identification of the determinants of protein thermal stabilization is often pursued by comparinPalabras claves:Infrared, Protein structure, Pyrococcus furiosus, Sulfolobus solfataricus, Thermosphaera aggregans, β-glycosidaseAutores:Alessio Ausili, Bertoli E., Cobucci-Ponzano B., D'Avino R., Di Lauro B., Moracci M., Perugino G., Rossi M., Scirè A., Tanfani F.Fuentes:googlescopusA comparison of the location in membranes of curcumin and curcumin-derived bivalent compounds with potential neuroprotective capacity for Alzheimer's disease
ArticleAbstract: Curcumin and two bivalent compounds, namely 17MD and 21MO, both obtained by conjugation of curcuminPalabras claves:1 H NOESY MAS-NMR, curcumin, dsc, Fluorescence quenching, membranesAutores:Alessio Ausili, Beltrán A., Candel A.M., Gómez-Murcia V., Gómez‐Fernández J.C., He L., Jiang Y., Teruel J.A., Torrecillas A., Zhang S.Fuentes:googlescopusA spectroscopic study on secondary structure and thermal unfolding of the plant toxin gelonin confirms some typical structural characteristics and unravels the sequence of thermal unfolding events
ArticleAbstract: Gelonin from the Indian plant Gelonium multiflorum belongs to the type I ribosome-inactivating protePalabras claves:Gelonin, Immunotoxins, Infrared spectroscopy, Ribosome-inactivating protein, Thermal unfolding, Two-dimensional correlation spectroscopyAutores:Alessio Ausili, Scirè A., Tanfani F.Fuentes:googlescopusDespite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study
ArticleAbstract: Heat shock proteins 90 (Hsp90) are chaperones that promote the proper folding of other proteins undePalabras claves:Human Hsp90, Infrared spectroscopy, Protein structure, Thermal stability, UnfoldingAutores:Alessio AusiliFuentes:googlescopusDiethylstilbestrol modifies the structure of model membranes and is localized close to the first carbons of the fatty acyl chains
ArticleAbstract: The synthetic estrogen diethylstilbestrol (DES) is used to treat metastatic carcinomas and prostatePalabras claves:1 H-NOESY-MAS-NMR, 31 P-NMR, Diethylstilbestrol, dsc, membranes, SAXD, Wide-angle X- ray diffraction (WAXD)Autores:Alessio Ausili, Gómez‐Fernández J.C., Rodríguez-gonzález I., Teruel J.A., Torrecillas A.Fuentes:googlescopusCorrelation between fluorescence and structure in the orange-emitting GFP-like protein, monomeric Kusabira Orange
ArticleAbstract: The mKO is the monomeric version of Kusabira Orange, a GFP-like protein emitting bright orange fluorPalabras claves:Fluorescent proteins, FTIR, mKO, Protein structure, Thermo-stabilityAutores:Alessio Ausili, D'Auria G., D’auria S., Gómez‐Fernández J.C., Marabotti A., Ortiz A., Staiano M., Torrecillas A.Fuentes:googlescopus