Mostrando 10 resultados de: 38
Publisher
Journal of Medicinal Chemistry(3)
Neuroscience(3)
Bioorganic and Medicinal Chemistry Letters(2)
British Journal of Pharmacology(2)
Neuropharmacology(2)
Cholecystokinin-mediated neuromodulation of anxiety and schizophrenia: A “dimmer-switch” hypothesis
ReviewAbstract: Cholecystokinin (CCK), the most abundant brain neuropeptide, is involved in relevant behavioral funcPalabras claves:anxiety, Cholecystokinin, dopamine, Gamma-aminobutyric acid, Glutamic acid, SchizophreniaAutores:Bourin M., Santiago J. BallazFuentes:googlescopusCommon laboratory tests as indicators of COVID-19 severity on admission at high altitude: A single-center retrospective study in Quito (ECUADOR)
OtherAbstract:Palabras claves:Biomarkers, Clinical laboratory techniques, covid-19, epidemiologyAutores:Esteban Fernández-Moreira, Francisco X. Mora, Hegira Ramírez, Kevin Chamorro, Martha M. Fors-López, Mary Pulgar-Sánchez, Santiago J. BallazFuentes:googlescopusComparison between RT-qPCR for SARS-CoV-2 and expanded triage in sputum of symptomatic and asymptomatic COVID-19 subjects in Ecuador
ArticleAbstract: Background: The quantitative reverse transcriptase-polymerase chain reaction (RT-qPCR) effectively dPalabras claves:covid-19, Rt-qPCR, SARS-CoV-2;sensitivity, SpecificityAutores:MARTHA FORS, Martha M. Fors-López, Pantoja K., Rivero T., Santiago J. Ballaz, Torres A.Fuentes:googlescopusBiomarkers of severe COVID-19 pneumonia on admission using data-mining powered by common laboratory blood tests-datasets
ArticleAbstract: In the epidemiological COVID-19 research, artificial intelligence is a unique approach to make pbkp_Palabras claves:Blood gas analyses, Clinical laboratory techniques, covid-19, Data Mining, Machine learning, Medical informatics applicationsAutores:Esteban Fernández-Moreira, Francisco X. Mora, Hegira Ramírez, Kevin Chamorro, MARTHA FORS, Martha M. Fors-López, Mary Pulgar-Sánchez, Santiago J. BallazFuentes:googlescopusBlockade of the cholecystokinin CCK-2 receptor prevents the normalization of anxiety levels in the rat
ArticleAbstract: Cholecystokinin (CCK), through the CCK-2 receptor, exerts complex effects on anxiety. While CCK agonPalabras claves:Behavior rating scale, Cholecystokinin, Cholecystokinin B, Performance anxiety, ReceptorAutores:Akil H., Bourin M., Santiago J. Ballaz, Watson S.J.Fuentes:googlescopusAnalysis of 5-HT6 and 5-HT7 receptor gene expression in rats showing differences in novelty-seeking behavior
ArticleAbstract: Sensation-seeking is a human personality trait associated with a greater propensity to use psychoactPalabras claves:5-HT, anxiety, Dentate gyrus, olfactory tubercle, thalamusAutores:Akil H., Santiago J. Ballaz, Watson S.J.Fuentes:googlescopusAnalysis of Socio-demographic, Economic and Individual Reasons for COVID-19 Vaccination Hesitancy in Ecuador: A Nationwide Longitudinal Study
ArticleAbstract: The current outbreak of SARS-Cov-2, a virus responsible for COVID-19, has infected millions and causPalabras claves:covid-19, sociodemographic factors, sociological factors, surveys and questionnaires, vaccination hesitancyAutores:Aline Siteneski, Diego E. Portalanza, German Josuet Lapo-Talledo, Jorge Andrés Talledo-Delgado, Santiago J. BallazFuentes:googlescopusAnti-Inflammatory Therapy as a Promising Target in Neuropsychiatric Disorders
Book PartAbstract: This chapter analyzes the therapeutic potential of current anti-inflammatory drugs in treating psychPalabras claves:anti-inflammatory agents, cytokines, glucocorticoids, inflammation, Mental Disorders, PsychoneuroimmunologyAutores:Bourin M., Santiago J. BallazFuentes:googlescopus2,5-Diketopiperidine derivatives as non-peptide ligands for cholecystokinin receptors
ArticleAbstract: Easily accessible 2,5-diketopiperidines have been used as templates for the construction of Trp-PhePalabras claves:Autores:Del Río J., Dominguez M.J., Fortuno A., Garcı́a-López M.T., Gonzalez-Muniz R., Herranz R., Santiago J. BallazFuentes:googlescopus2-Oxopyrrolidines and 6-oxoperhydropyrrolo[1,2-a]pyrazines as templates in the search for nonpeptide cholecystokinin ligands
ArticleAbstract: In order to find new classes of non-peptide cholecystokinin (CCK) ligands, the conformational restriPalabras claves:2-Oxopyrrolidine, Cholecystokinin mimetic, Perhydropyrrolo[1,2-a]pyrazineAutores:Cenarruzabeitia E., Del Río J., Garcı́a-López M.T., Gonzalez-Muniz R., Herranz R., LaTorre M., Martín-Martínez M., Santiago J. BallazFuentes:googlescopus